diff --git a/packages/s2-core/__tests__/unit/data-set/pivot-data-set-spec.ts b/packages/s2-core/__tests__/unit/data-set/pivot-data-set-spec.ts
index 2206b0f4b4..ab9f72ce28 100644
--- a/packages/s2-core/__tests__/unit/data-set/pivot-data-set-spec.ts
+++ b/packages/s2-core/__tests__/unit/data-set/pivot-data-set-spec.ts
@@ -158,6 +158,10 @@ describe('Pivot Dataset Test', () => {
         getDimensionsWithoutPathPre(sortedDimensionValues[EXTRA_FIELD]),
       ).toEqual(['number', 'number', 'number', 'number']);
     });
+
+    test('should get correctly empty dataset result', () => {
+      expect(dataSet.isEmpty()).toBeFalsy();
+    });
   });
 
   describe('test for query data', () => {
diff --git a/packages/s2-core/__tests__/unit/data-set/table-data-set-spec.ts b/packages/s2-core/__tests__/unit/data-set/table-data-set-spec.ts
index 4da12e138b..8e990596c3 100644
--- a/packages/s2-core/__tests__/unit/data-set/table-data-set-spec.ts
+++ b/packages/s2-core/__tests__/unit/data-set/table-data-set-spec.ts
@@ -99,6 +99,10 @@ describe('Table Mode Dataset Test', () => {
     test('should get correct meta data', () => {
       expect(dataSet.meta).toEqual(expect.objectContaining([]));
     });
+
+    test('should get correctly empty dataset result', () => {
+      expect(dataSet.isEmpty()).toBeFalsy();
+    });
   });
 
   describe('test for query data', () => {
diff --git a/packages/s2-core/__tests__/unit/facet/table-facet-spec.ts b/packages/s2-core/__tests__/unit/facet/table-facet-spec.ts
index 428e07a9fa..ad72e6226a 100644
--- a/packages/s2-core/__tests__/unit/facet/table-facet-spec.ts
+++ b/packages/s2-core/__tests__/unit/facet/table-facet-spec.ts
@@ -13,9 +13,11 @@ import { DataCell, DEFAULT_STYLE, type Fields, Node } from '@/index';
 import { getFrozenLeafNodesCount } from '@/facet/utils';
 import { SpreadSheet } from '@/sheet-type';
 import { getTheme } from '@/theme';
+
 const actualDataSet = jest.requireActual(
   '@/data-set/base-data-set',
 ).BaseDataSet;
+
 jest.mock('@/sheet-type', () => {
   const container = new Canvas({
     width: 100,
@@ -59,6 +61,9 @@ jest.mock('@/sheet-type', () => {
         interaction: {
           clearHoverTimer: jest.fn(),
         },
+        dataSet: {
+          isEmpty: jest.fn(),
+        },
       };
     }),
   };
@@ -77,6 +82,7 @@ jest.mock('@/data-set/table-data-set', () => {
         getCellData: () => 1,
         getFieldMeta: jest.fn(),
         getFieldFormatter: actualDataSet.prototype.getFieldFormatter,
+        isEmpty: jest.fn(),
       };
     }),
   };
diff --git a/packages/s2-core/src/cell/table-col-cell.ts b/packages/s2-core/src/cell/table-col-cell.ts
index 3368f9ffd6..be1c6a04c4 100644
--- a/packages/s2-core/src/cell/table-col-cell.ts
+++ b/packages/s2-core/src/cell/table-col-cell.ts
@@ -77,6 +77,7 @@ export class TableColCell extends ColCell {
         y,
       };
     }
+
     return {
       x: position.x + x - scrollX,
       y: position.y + y,
diff --git a/packages/s2-core/src/data-set/base-data-set.ts b/packages/s2-core/src/data-set/base-data-set.ts
index 1c95f5e736..92ffb6ae8e 100644
--- a/packages/s2-core/src/data-set/base-data-set.ts
+++ b/packages/s2-core/src/data-set/base-data-set.ts
@@ -3,6 +3,7 @@ import {
   find,
   get,
   identity,
+  isEmpty,
   isNil,
   map,
   max,
@@ -117,6 +118,10 @@ export abstract class BaseDataSet {
     return this.displayData;
   }
 
+  public isEmpty() {
+    return isEmpty(this.getDisplayDataSet());
+  }
+
   public getValueRangeByField(field: string): ValueRange {
     const cacheRange = getValueRangeState(this.spreadsheet, field);
     if (cacheRange) {
diff --git a/packages/s2-core/src/facet/table-facet.ts b/packages/s2-core/src/facet/table-facet.ts
index 0cd0f14ed2..e1608eb241 100644
--- a/packages/s2-core/src/facet/table-facet.ts
+++ b/packages/s2-core/src/facet/table-facet.ts
@@ -43,7 +43,7 @@ import {
   getFrozenRowsForGrid,
   getRowsForGrid,
 } from '../utils/grid';
-import type { PanelIndexes } from '../utils/indexes';
+import type { Indexes, PanelIndexes } from '../utils/indexes';
 import { getValidFrozenOptions } from '../utils/layout/frozen';
 import { BaseFacet } from './base-facet';
 import { CornerBBox } from './bbox/cornerBBox';
@@ -1129,14 +1129,17 @@ export class TableFacet extends BaseFacet {
       }
     }
 
-    const indexes = calculateInViewIndexes(
-      scrollX,
-      scrollY,
-      this.viewCellWidths,
-      this.viewCellHeights,
-      finalViewport,
-      this.getRealScrollX(this.cornerBBox.width),
-    );
+    // https://github.com/antvis/S2/issues/2255
+    const indexes = this.spreadsheet.dataSet.isEmpty()
+      ? ([] as unknown as Indexes)
+      : calculateInViewIndexes(
+          scrollX,
+          scrollY,
+          this.viewCellWidths,
+          this.viewCellHeights,
+          finalViewport,
+          this.getRealScrollX(this.cornerBBox.width),
+        );
 
     this.panelScrollGroupIndexes = indexes;
 
diff --git a/packages/s2-core/src/sheet-type/table-sheet.ts b/packages/s2-core/src/sheet-type/table-sheet.ts
index 3612f9d960..21f372f269 100644
--- a/packages/s2-core/src/sheet-type/table-sheet.ts
+++ b/packages/s2-core/src/sheet-type/table-sheet.ts
@@ -123,6 +123,7 @@ export class TableSheet extends SpreadSheet {
       }
       return new TableDataCell(facet, this);
     };
+
     return {
       ...this.options,
       ...fields,
diff --git a/s2-site/docs/api/basic-class/base-data-set.zh.md b/s2-site/docs/api/basic-class/base-data-set.zh.md
index 3b8523fc5a..b259e92ced 100644
--- a/s2-site/docs/api/basic-class/base-data-set.zh.md
+++ b/s2-site/docs/api/basic-class/base-data-set.zh.md
@@ -28,6 +28,7 @@ s2.dataSet.getFieldName('type')
 | getCellData         | 获取单个的单元格数据               | (params: [CellDataParams](#celldataparams)) => [DataType[]](#datatype) |                                             |
 | getMultiData        | 获取批量的单元格数据               | (query: [DataType](#datatype), isTotals?: boolean, isRow?: boolean, drillDownFields?: string[]) => [DataType[]](#datatype) |                                             |
 | moreThanOneValue    | 是否超过 1 个数值                  | () => [ViewMeta](#viewmeta)                                  |                                             |
+| isEmpty    | 是否为空数据集                 | () => `boolean`                                 |      `@antv/s2-v1.51.1`                                       |
 
 ### DataType