diff --git a/build/yamls/antrea-prometheus.yml b/build/yamls/antrea-prometheus.yml
index 8a94b9185e7..79ead678fec 100644
--- a/build/yamls/antrea-prometheus.yml
+++ b/build/yamls/antrea-prometheus.yml
@@ -136,7 +136,8 @@ spec:
     spec:
       containers:
         - name: prometheus
-          image: projects.registry.vmware.com/antrea/prom-prometheus:v2.19.3
+          image: ubuntu/prometheus:2.46.0-22.04_stable
+          command: [ "/bin/prometheus" ]
           args:
             - "--config.file=/etc/prometheus/prometheus.yml"
             - "--storage.tsdb.path=/prometheus/"
diff --git a/docs/prometheus-integration.md b/docs/prometheus-integration.md
index 7fa896937e1..53a7480b304 100644
--- a/docs/prometheus-integration.md
+++ b/docs/prometheus-integration.md
@@ -27,7 +27,7 @@ parameter to true in the Controller and the Agent configurations.
 
 ### Prometheus version
 
-Prometheus integration with Antrea is validated as part of CI using Prometheus v2.19.3.
+Prometheus integration with Antrea is validated as part of CI using Prometheus v2.46.0.
 
 ### Prometheus RBAC
 
diff --git a/test/e2e/prometheus_test.go b/test/e2e/prometheus_test.go
index 568225e0849..25ce5354ba0 100644
--- a/test/e2e/prometheus_test.go
+++ b/test/e2e/prometheus_test.go
@@ -279,7 +279,7 @@ func testMetricsFromPrometheusServer(t *testing.T, data *TestData, prometheusJob
 
 	// Build the Prometheus query URL
 	// Target metadata API(/api/v1/targets/metadata) has been available since Prometheus v2.4.0.
-	// This API is still experimental in Prometheus v2.19.3.
+	// This API is still experimental in Prometheus v2.46.0.
 	path := url.PathEscape("match_target={job=\"" + prometheusJob + "\"}")
 	address := net.JoinHostPort(hostIP, fmt.Sprint(nodePort))
 	queryURL := fmt.Sprintf("http://%s/api/v1/targets/metadata?%s", address, path)