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<article>
<div class="standard-teaser media-none clear">
<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21501.html">Physiology: Bone-derived hormone suppresses appetite</a>
</h1>
<p class="standfirst"><stndfrst>The glycoprotein lipocalin 2 is released from the bones of mice in a nutrient-dependent manner and binds to receptors in the brain to suppress appetite. This is the first example of bone-derived signals mediating hunger.</stndfrst></p>
<ul class="authors limited">
<li>Richard D. Palmiter</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/nature21501</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21501.html">Full Text</a></li>
<li><a href="/nature/journal/vaop/ncurrent/pdf/nature21501.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=378">Neuroscience</a></li>
<li><a href="/nature/archive/subject.html?code=443">Physiology</a></li>
</ul>
</div>
</article>
</li>
<li class="even">
<article>
<div class="standard-teaser media-none clear">
<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21893.html">Molecular biology: A hidden competitive advantage of disorder</a>
</h1>
<p class="standfirst"><stndfrst>The cellular response to low oxygen levels is regulated by a process in which one protein is ousted from a binding site by another. It emerges that protein disorder allows the displacement to occur remarkably efficiently.</stndfrst></p>
<ul class="authors limited">
<li>P. Andrew Chong</li>
<li>Julie D. Forman-Kay</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/nature21893</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21893.html">Full Text</a></li>
<li><a href="/nature/journal/vaop/ncurrent/pdf/nature21893.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=57">Biophysics</a></li>
<li><a href="/nature/archive/subject.html?code=337">Molecular biology</a></li>
<li><a href="/nature/archive/subject.html?code=535">Structural biology</a></li>
</ul>
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</article>
</li>
<li class="odd">
<article>
<div class="standard-teaser media-none clear">
<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/543183a.html">Non-coding RNA: More uses for genomic junk</a>
</h1>
<p class="standfirst"><stndfrst>It emerges that nascent non-coding RNAs transcribed from regulatory DNA sequences called enhancers bind to the enzyme CBP to promote its activity locally. In turn, the activities of CBP stimulate further enhancer transcription.</stndfrst></p>
<ul class="authors limited">
<li>Karen Adelman</li>
<li>Emily Egan</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 183–185 (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/543183a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/543183a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/543183a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=176">Epigenetics</a></li>
<li><a href="/nature/archive/subject.html?code=337">Molecular biology</a></li>
<li><a href="/nature/archive/subject.html?code=384">Non-coding RNAs</a></li>
</ul>
</div>
</article>
</li>
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<article>
<div class="standard-teaser media-none clear">
<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/543185a.html">Condensed-matter physics: Marching to a different quantum beat</a>
</h1>
<p class="standfirst"><stndfrst>Periodic oscillations are common in nature but they generally decay or fall out of phase. Two experiments have found evidence for a Floquet time crystal, which is characterized by persistent in-phase oscillations. <b>See Letters </b> <xnav extrefid="nature21413">p.217</xnav> & <xnav extrefid="nature21426">p. 221</xnav></stndfrst></p>
<ul class="authors limited">
<li>Chetan Nayak</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 185–186 (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/543185a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/543185a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/543185a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=119">Condensed-matter physics</a></li>
<li><a href="/nature/archive/subject.html?code=483">Quantum physics</a></li>
</ul>
</div>
</article>
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<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/543187a.html">50 & 100 Years Ago</a>
</h1>
<p class="standfirst"></p>
<ul class="authors limited">
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 187 (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/543187a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/543187a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/543187a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=236">History</a></li>
<li><a href="/nature/archive/subject.html?code=522">Society</a></li>
<li><a href="/nature/archive/subject.html?code=535">Structural biology</a></li>
</ul>
</div>
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<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/543188a.html">Archaeology: Digital maps illuminate ancient trade routes</a>
</h1>
<p class="standfirst"><stndfrst>How did the relationship between human societies and their surrounding terrain shape the formation of long-distance trade networks such as the Silk Road? Digital mapping and computer modelling offer insights. <b>See Article </b> <xnav extrefid="nature21696">p.193</xnav></stndfrst></p>
<ul class="authors limited">
<li>Michael J. Harrower</li>
<li>Ioana A. Dumitru</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 188–189 (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/543188a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/543188a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/543188a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=27">Archaeology</a></li>
<li><a href="/nature/archive/subject.html?code=2808">Geography</a></li>
</ul>
</div>
</article>
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<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/543189a.html">Nanoscience: Single-atom data storage</a>
</h1>
<p class="standfirst"><stndfrst>The ultimate limit of classical data storage is a single-atom magnetic bit. Researchers have now achieved the writing and reading of individual atoms whose magnetic information can be retained for several hours. <b>See Letter </b> <xnav extrefid="nature21371">p.226</xnav></stndfrst></p>
<ul class="authors limited">
<li>Roberta Sessoli</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 189–190 (<time datetime="2017-03-08" ><span class="time">08 March 2017</span></time>) | doi:10.1038/543189a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/543189a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/543189a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=119">Condensed-matter physics</a></li>
<li><a href="/nature/archive/subject.html?code=301">Materials science</a></li>
<li><a href="/nature/archive/subject.html?code=925">Nanoscience and technology</a></li>
</ul>
</div>
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<span>News and Views</span> <a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21892.html">Cell biology: Sort and destroy</a>
</h1>
<p class="standfirst"><stndfrst>Aggregates are aberrant, non-functional forms of protein that often build up in cells in response to stress. Organelles called mitochondria have now been found to be active players in the clearance of these protein aggregates.</stndfrst></p>
<ul class="authors limited">
<li>Agnieszka Chacinska</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> (<time datetime="2017-03-01" ><span class="time">01 March 2017</span></time>) | doi:10.1038/nature21892</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/vaop/ncurrent/full/nature21892.html">Full Text</a></li>
<li><a href="/nature/journal/vaop/ncurrent/pdf/nature21892.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=80">Cell biology</a></li>
</ul>
</div>
</article>
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<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7643/full/543042a.html">Materials science: Lessons from tooth enamel</a>
</h1>
<p class="standfirst"><stndfrst>A remarkable composite material has been made that mimics the structure of tooth enamel. This achievement opens up the exploration of new composite materials and of computational methods that reliably predict their properties. <b>See Letter </b> <xnav extrefid="nature21410">p.95</xnav></stndfrst></p>
<ul class="authors limited">
<li>Horacio D. Espinosa</li>
<li>Rafael Soler-Crespo</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 42–43 (<time datetime="2017-03-01" ><span class="time">01 March 2017</span></time>) | doi:10.1038/543042a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7643/full/543042a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7643/pdf/543042a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=301">Materials science</a></li>
</ul>
</div>
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<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7643/full/543044a.html">Geoscience: Subduction undone</a>
</h1>
<p class="standfirst"><stndfrst>Rocks are subjected to increased pressure as they are buried during subduction. Contrary to general belief, a study suggests that peak pressures recorded in subducted rocks might not reflect their maximum burial depths.</stndfrst></p>
<ul class="authors limited">
<li>Kip V. Hodges</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 44–45 (<time datetime="2017-03-01" ><span class="time">01 March 2017</span></time>) | doi:10.1038/543044a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7643/full/543044a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7643/pdf/543044a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=213">Geology</a></li>
<li><a href="/nature/archive/subject.html?code=2809">Geophysics</a></li>
<li><a href="/nature/archive/subject.html?code=2151">Solid Earth sciences</a></li>
</ul>
</div>
</article>
</li>
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<h1>
<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7643/full/543047a.html">Quantum physics: A solid more fluid than a fluid</a>
</h1>
<p class="standfirst"><stndfrst>A supersolid is a paradoxical and elusive state of matter that has been sought for more than 60 years. Two experiments have now observed its characteristic signatures in ultracold quantum matter. <b>See Letters </b> <xnav extrefid="nature21067">p.87</xnav> & <xnav extrefid="nature21431">p.91</xnav></stndfrst></p>
<ul class="authors limited">
<li>Kaden R. A. Hazzard</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 47–48 (<time datetime="2017-03-01" ><span class="time">01 March 2017</span></time>) | doi:10.1038/543047a</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7643/full/543047a.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7643/pdf/543047a.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=36">Atomic and molecular physics</a></li>
<li><a href="/nature/archive/subject.html?code=119">Condensed-matter physics</a></li>
<li><a href="/nature/archive/subject.html?code=483">Quantum physics</a></li>
</ul>
</div>
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<span>News and Views</span> <a href="http://www.nature.com/nature/journal/v543/n7644/full/nature21894.html">Cancer epigenetics: Reading the future of leukaemia</a>
</h1>
<p class="standfirst"><stndfrst>The identification of the regulatory protein ENL as essential to an aggressive form of leukaemia provides insight into transcriptional regulation and highlights potential avenues for therapy. <b>See Letters </b> <xnav extrefid="nature21687">p.265</xnav> & <xnav extrefid="nature21688">p.270</xnav></stndfrst></p>
<ul class="authors limited">
<li>Alex W. Wilkinson</li>
<li>Or Gozani</li>
</ul>
<p class="citation"><span class="journal-title">Nature</span> <span class="volume">543</span>, 186–188 (<time datetime="2017-03-01" ><span class="time">01 March 2017</span></time>) | doi:10.1038/nature21894</p>
<ul class="links">
<li><a href="http://www.nature.com/nature/journal/v543/n7644/full/nature21894.html">Full Text</a></li>
<li><a href="/nature/journal/v543/n7644/pdf/nature21894.pdf">PDF</a></li> </ul>
<ul class="tags">
<li><a href="/nature/archive/subject.html?code=67">Cancer</a></li>