diff --git a/docs/how-to-guides/themes/theme-json.md b/docs/how-to-guides/themes/theme-json.md
index d1f0df50ed148..f2465e4df1082 100644
--- a/docs/how-to-guides/themes/theme-json.md
+++ b/docs/how-to-guides/themes/theme-json.md
@@ -183,6 +183,7 @@ The settings section has the following structure and default values:
       "color": {
         "custom": true, /* false to opt-out, as in add_theme_support('disable-custom-colors') */
         "customGradient": true, /* false to opt-out, as in add_theme_support('disable-custom-gradients') */
+        "duotone": [ ... ], /* duotone presets, a list of { "colors": [ "#000", "#FFF" ], "slug": "black-and-white", "name": "Black and White" } */
         "gradients": [ ... ], /* gradient presets, as in add_theme_support('editor-gradient-presets', ... ) */
         "link": false, /* true to opt-in, as in add_theme_support('experimental-link-color') */
         "palette": [ ... ], /* color presets, as in add_theme_support('editor-color-palette', ... ) */
diff --git a/docs/reference-guides/block-api/block-supports.md b/docs/reference-guides/block-api/block-supports.md
index 565b1f0bbbd8e..ff3f50cad8d85 100644
--- a/docs/reference-guides/block-api/block-supports.md
+++ b/docs/reference-guides/block-api/block-supports.md
@@ -86,12 +86,11 @@ supports: {
 -   Default value: null
 -   Subproperties:
     -   `background`: type `boolean`, default value `true`
+    -   `duotone`: type `string`, default value undefined
     -   `gradients`: type `boolean`, default value `false`
     -   `text`: type `boolean`, default value `true`
 
-This value signals that a block supports some of the CSS style properties related to color. When it does, the block editor will show UI controls for the user to set their values.
-
-The controls for background and text will source their colors from the `editor-color-palette` [theme support](https://developer.wordpress.org/block-editor/developers/themes/theme-support/#block-color-palettes), while the gradient's from `editor-gradient-presets` [theme support](https://developer.wordpress.org/block-editor/developers/themes/theme-support/#block-gradient-presets).
+This value signals that a block supports some of the properties related to color. When it does, the block editor will show UI controls for the user to set their values.
 
 Note that the `text` and `background` keys have a default value of `true`, so if the `color` property is present they'll also be considered enabled:
 
@@ -115,58 +114,227 @@ supports: {
 }
 ```
 
-When the block has support for a specific color property, the attributes definition is extended to include some attributes.
+### color.background
+
+This property adds UI controls which allow the user to apply a solid background color to a block.
 
--   `style`: attribute of `object` type with no default assigned. This is added when any of support color properties are declared. It stores the custom values set by the user. The block can apply a default style by specifying its own `style` attribute with a default e.g.:
+When color support is declared, this property is enabled by default (along with text), so simply setting color will enable background color.
 
 ```js
-attributes: {
-    style: {
-        type: 'object',
-        default: {
-            color: {
-                background: 'value',
-                gradient: 'value',
-                text: 'value'
-            }
-        }
+supports: {
+    color: true // Enable both background and text
+}
+```
+
+To disable background support while keeping other color supports enabled, set to `false`.
+
+```js
+supports: {
+    color: {
+        // Disable background support. Text color support is still enabled.
+        background: false
     }
 }
 ```
 
--   When `background` support is declared: it'll be added a new `backgroundColor` attribute of type `string` with no default assigned. It stores the preset values set by the user. The block can apply a default background color by specifying its own attribute with a default e.g.:
+When the block declares support for `color.background`, the attributes definition is extended to include two new attributes: `backgroundColor` and `style`:
+
+- `backgroundColor`: attribute of `string` type with no default assigned.
+
+  When a user chooses from the list of preset background colors, the preset slug is stored in the `backgroundColor` attribute.
+
+  Background color presets are sourced from the `editor-color-palette` [theme support](https://developer.wordpress.org/block-editor/developers/themes/theme-support/#block-color-palettes).
+
+  The block can apply a default preset background color by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      backgroundColor: {
+          type: 'string',
+          default: 'some-preset-background-slug',
+      }
+  }
+  ```
+
+- `style`: attribute of `object` type with no default assigned.
+  
+  When a custom background color is selected (i.e. using the custom color picker), the custom color value is stored in the `style.color.background` attribute.
+
+  The block can apply a default custom background color by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      style: {
+          type: 'object',
+          default: {
+              color: {
+                  background: '#aabbcc',
+              }
+          }
+      }
+  }
+  ```
+
+### color.__experimentalDuotone
+
+This property adds UI controls which allow to apply a duotone filter to a block or part of a block.
+
+The parent selector is automatically added much like nesting in Sass/SCSS (however, the `&` selector is not supported).
 
 ```js
-attributes: {
-    backgroundColor: {
-        type: 'string',
-        default: 'some-value',
+supports: {
+    color: {
+        // Apply the filter to the same selector in both edit and save.
+        __experimentalDuotone: '> .duotone-img, > .duotone-video',
+
+        // Default values must be disabled if you don't want to use them with duotone.
+        background: false,
+        text: false
     }
 }
 ```
 
--   When `gradients` support is declared: it'll be added a new `gradient` attribute of type `string` with no default assigned. It stores the preset values set by the user. The block can apply a default text color by specifying its own attribute with a default e.g.:
+Duotone presets are sourced from `color.duotone` in [theme.json](https://developer.wordpress.org/block-editor/developers/themes/theme-json/).
+
+When the block declares support for `color.duotone`, the attributes definition is extended to include the attribute `style`:
+
+- `style`: attribute of `object` type with no default assigned.
+
+  The block can apply a default duotone color by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      style: {
+          type: 'object',
+          default: {
+              color: {
+                  duotone: [
+                      '#FFF',
+                      '#000
+                  ]
+              }
+          }
+      }
+  }
+  ```
+
+### color.gradients
+
+This property adds UI controls which allow the user to apply a gradient background to a block.
 
 ```js
-attributes: {
-    gradient: {
-        type: 'string',
-        default: 'some-value',
+supports: {
+    color: {
+        gradient: true,
+
+        // Default values must be disabled if you don't want to use them with gradient.
+        background: false,
+        text: false
     }
 }
 ```
 
--   When `text` support is declared: it'll be added a new `textColor` attribute of type `string` with no default assigned. It stores the preset values set by the user. The block can apply a default text color by specifying its own attribute with a default e.g.:
+Gradient presets are sourced from `editor-gradient-presets` [theme support](https://developer.wordpress.org/block-editor/developers/themes/theme-support/#block-gradient-presets).
+
+
+When the block declares support for `color.gradient`, the attributes definition is extended to include two new attributes: `gradient` and `style`:
+
+- `gradient`: attribute of `string` type with no default assigned.
+
+  When a user chooses from the list of preset gradients, the preset slug is stored in the `gradient` attribute.
+
+  The block can apply a default preset gradient by specifying its own attribute with a default e.g.:
+  
+  ```js
+  attributes: {
+      gradient: {
+          type: 'string',
+          default: 'some-preset-gradient-slug',
+      }
+  }
+  ```
+
+- `style`: attribute of `object` type with no default assigned.
+  
+  When a custom gradient is selected (i.e. using the custom gradient picker), the custom gradient value is stored in the `style.color.gradient` attribute.
+  
+  The block can apply a default custom gradient by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      style: {
+          type: 'object',
+          default: {
+              color: {
+                  background: 'linear-gradient(135deg,rgb(170,187,204) 0%,rgb(17,34,51) 100%)',
+              }
+          }
+      }
+  }
+  ```
+
+### color.text
+
+This property adds block controls which allow the user to set text color in a block.
+
+When color support is declared, this property is enabled by default (along with background), so simply setting color will enable text color.
 
 ```js
-attributes: {
-    textColor: {
-        type: 'string',
-        default: 'some-value',
+supports: {
+    color: true // Enable both text and background
+}
+```
+
+To disable text color support while keeping other color supports enabled, set to `false`.
+
+```js
+supports: {
+    color: {
+        // Disable text color support. Background support is still enabled.
+        text: false
     }
 }
 ```
 
+Text color presets are sourced from the `editor-color-palette` [theme support](https://developer.wordpress.org/block-editor/developers/themes/theme-support/#block-color-palettes).
+  
+
+When the block declares support for `color.text`, the attributes definition is extended to include two new attributes: `textColor` and `style`:
+
+- `textColor`: attribute of `string` type with no default assigned.
+
+  When a user chooses from the list of preset text colors, the preset slug is stored in the `textColor` attribute.
+  
+  The block can apply a default preset text color by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      textColor: {
+          type: 'string',
+          default: 'some-preset-text-color-slug',
+      }
+  }
+  ```
+
+- `style`: attribute of `object` type with no default assigned.
+  
+  When a custom text color is selected (i.e. using the custom color picker), the custom color value is stored in the `style.color.text` attribute.
+  
+  The block can apply a default custom text color by specifying its own attribute with a default e.g.:
+
+  ```js
+  attributes: {
+      style: {
+          type: 'object',
+          default: {
+              color: {
+                  text: '#aabbcc',
+              }
+          }
+      }
+  }
+  ```
+
 ## customClassName
 
 -   Type: `boolean`
diff --git a/lib/block-supports/duotone.php b/lib/block-supports/duotone.php
new file mode 100644
index 0000000000000..f3b4743832f0a
--- /dev/null
+++ b/lib/block-supports/duotone.php
@@ -0,0 +1,364 @@
+<?php
+/**
+ * Duotone block support flag.
+ *
+ * @package gutenberg
+ */
+
+/**
+ * Direct port of tinycolor's bound01 function, lightly simplified to maintain
+ * consistency with tinycolor.
+ *
+ * @see https://github.com/bgrins/TinyColor
+ *
+ * @param  mixed $n   Number of unknown type.
+ * @param  int   $max Upper value of the range to bound to.
+ * @return float      Value in the range [0,1].
+ */
+function gutenberg_tinycolor_bound01( $n, $max ) {
+	if ( 'string' === gettype( $n ) && false !== strpos( $n, '.' ) && 1 === (float) $n ) {
+		$n = '100%';
+	}
+
+	$n = min( $max, max( 0, (float) $n ) );
+
+	// Automatically convert percentage into number.
+	if ( 'string' === gettype( $n ) && false !== strpos( $n, '%' ) ) {
+		$n = (int) ( $n * $max ) / 100;
+	}
+
+	// Handle floating point rounding errors.
+	if ( ( abs( $n - $max ) < 0.000001 ) ) {
+		return 1.0;
+	}
+
+	// Convert into [0, 1] range if it isn't already.
+	return ( $n % $max ) / (float) $max;
+}
+
+/**
+ * Round and convert values of an RGB object.
+ *
+ * @see https://github.com/bgrins/TinyColor
+ *
+ * @param  array $rgb_color RGB object.
+ * @return array            Rounded and converted RGB object.
+ */
+function gutenberg_tinycolor_rgb_to_rgb( $rgb_color ) {
+	return array(
+		'r' => gutenberg_tinycolor_bound01( $rgb_color['r'], 255 ) * 255,
+		'g' => gutenberg_tinycolor_bound01( $rgb_color['g'], 255 ) * 255,
+		'b' => gutenberg_tinycolor_bound01( $rgb_color['b'], 255 ) * 255,
+	);
+}
+
+/**
+ * Helper function for hsl to rgb conversion.
+ *
+ * @see https://github.com/bgrins/TinyColor
+ *
+ * @param  float $p first component.
+ * @param  float $q second component.
+ * @param  float $t third component.
+ * @return float    R, G, or B component.
+ */
+function gutenberg_tinycolor_hue_to_rgb( $p, $q, $t ) {
+	if ( $t < 0 ) {
+		$t += 1;
+	}
+	if ( $t > 1 ) {
+		$t -= 1;
+	}
+	if ( $t < 1 / 6 ) {
+		return $p + ( $q - $p ) * 6 * $t;
+	}
+	if ( $t < 1 / 2 ) {
+		return $q;
+	}
+	if ( $t < 2 / 3 ) {
+		return $p + ( $q - $p ) * ( 2 / 3 - $t ) * 6;
+	}
+	return $p;
+}
+
+/**
+ * Convert an HSL object to an RGB object with converted and rounded values.
+ *
+ * @see https://github.com/bgrins/TinyColor
+ *
+ * @param  array $hsl_color HSL object.
+ * @return array            Rounded and converted RGB object.
+ */
+function gutenberg_tinycolor_hsl_to_rgb( $hsl_color ) {
+	$h = gutenberg_tinycolor_bound01( $hsl_color['h'], 360 );
+	$s = gutenberg_tinycolor_bound01( $hsl_color['s'], 100 );
+	$l = gutenberg_tinycolor_bound01( $hsl_color['l'], 100 );
+
+	if ( 0 === $s ) {
+		// Achromatic.
+		$r = $l;
+		$g = $l;
+		$b = $l;
+	} else {
+		$q = $l < 0.5 ? $l * ( 1 + $s ) : $l + $s - $l * $s;
+		$p = 2 * $l - $q;
+		$r = gutenberg_tinycolor_hue_to_rgb( $p, $q, $h + 1 / 3 );
+		$g = gutenberg_tinycolor_hue_to_rgb( $p, $q, $h );
+		$b = gutenberg_tinycolor_hue_to_rgb( $p, $q, $h - 1 / 3 );
+	}
+
+	return array(
+		'r' => $r * 255,
+		'g' => $g * 255,
+		'b' => $b * 255,
+	);
+}
+
+/**
+ * Parses hex, hsl, and rgb CSS strings using the same regex as tinycolor v1.4.2
+ * used in the JavaScript. Only colors output from react-color are implemented
+ * and the alpha value is ignored as it is not used in duotone.
+ *
+ * @see https://github.com/bgrins/TinyColor
+ * @see https://github.com/casesandberg/react-color/
+ *
+ * @param  string $color_str CSS color string.
+ * @return array             RGB object.
+ */
+function gutenberg_tinycolor_string_to_rgb( $color_str ) {
+	$color_str = strtolower( trim( $color_str ) );
+
+	$css_integer = '[-\\+]?\\d+%?';
+	$css_number  = '[-\\+]?\\d*\\.\\d+%?';
+
+	$css_unit = '(?:' . $css_number . ')|(?:' . $css_integer . ')';
+
+	$permissive_match3 = '[\\s|\\(]+(' . $css_unit . ')[,|\\s]+(' . $css_unit . ')[,|\\s]+(' . $css_unit . ')\\s*\\)?';
+	$permissive_match4 = '[\\s|\\(]+(' . $css_unit . ')[,|\\s]+(' . $css_unit . ')[,|\\s]+(' . $css_unit . ')[,|\\s]+(' . $css_unit . ')\\s*\\)?';
+
+	$rgb_regexp = '/^rgb' . $permissive_match3 . '$/';
+	if ( preg_match( $rgb_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => $match[1],
+				'g' => $match[2],
+				'b' => $match[3],
+			)
+		);
+	}
+
+	$rgba_regexp = '/^rgba' . $permissive_match4 . '$/';
+	if ( preg_match( $rgba_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => $match[1],
+				'g' => $match[2],
+				'b' => $match[3],
+			)
+		);
+	}
+
+	$hsl_regexp = '/^hsl' . $permissive_match3 . '$/';
+	if ( preg_match( $hsl_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_hsl_to_rgb(
+			array(
+				'h' => $match[1],
+				's' => $match[2],
+				'l' => $match[3],
+			)
+		);
+	}
+
+	$hsla_regexp = '/^hsla' . $permissive_match4 . '$/';
+	if ( preg_match( $hsla_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_hsl_to_rgb(
+			array(
+				'h' => $match[1],
+				's' => $match[2],
+				'l' => $match[3],
+			)
+		);
+	}
+
+	$hex8_regexp = '/^#?([0-9a-fA-F]{2})([0-9a-fA-F]{2})([0-9a-fA-F]{2})([0-9a-fA-F]{2})$/';
+	if ( preg_match( $hex8_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => base_convert( $match[1], 16, 10 ),
+				'g' => base_convert( $match[2], 16, 10 ),
+				'b' => base_convert( $match[3], 16, 10 ),
+			)
+		);
+	}
+
+	$hex6_regexp = '/^#?([0-9a-fA-F]{2})([0-9a-fA-F]{2})([0-9a-fA-F]{2})$/';
+	if ( preg_match( $hex6_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => base_convert( $match[1], 16, 10 ),
+				'g' => base_convert( $match[2], 16, 10 ),
+				'b' => base_convert( $match[3], 16, 10 ),
+			)
+		);
+	}
+
+	$hex4_regexp = '/^#?([0-9a-fA-F]{1})([0-9a-fA-F]{1})([0-9a-fA-F]{1})([0-9a-fA-F]{1})$/';
+	if ( preg_match( $hex4_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => base_convert( $match[1] . $match[1], 16, 10 ),
+				'g' => base_convert( $match[2] . $match[2], 16, 10 ),
+				'b' => base_convert( $match[3] . $match[3], 16, 10 ),
+			)
+		);
+	}
+
+	$hex3_regexp = '/^#?([0-9a-fA-F]{1})([0-9a-fA-F]{1})([0-9a-fA-F]{1})$/';
+	if ( preg_match( $hex3_regexp, $color_str, $match ) ) {
+		return gutenberg_tinycolor_rgb_to_rgb(
+			array(
+				'r' => base_convert( $match[1] . $match[1], 16, 10 ),
+				'g' => base_convert( $match[2] . $match[2], 16, 10 ),
+				'b' => base_convert( $match[3] . $match[3], 16, 10 ),
+			)
+		);
+	}
+}
+
+
+/**
+ * Registers the style and colors block attributes for block types that support it.
+ *
+ * @param WP_Block_Type $block_type Block Type.
+ */
+function gutenberg_register_duotone_support( $block_type ) {
+	$has_duotone_support = false;
+	if ( property_exists( $block_type, 'supports' ) ) {
+		$has_duotone_support = _wp_array_get( $block_type->supports, array( 'color', '__experimentalDuotone' ), false );
+	}
+
+	if ( $has_duotone_support ) {
+		if ( ! $block_type->attributes ) {
+			$block_type->attributes = array();
+		}
+
+		if ( ! array_key_exists( 'style', $block_type->attributes ) ) {
+			$block_type->attributes['style'] = array(
+				'type' => 'object',
+			);
+		}
+	}
+}
+
+/**
+ * Render out the duotone stylesheet and SVG.
+ *
+ * @param  string $block_content Rendered block content.
+ * @param  array  $block         Block object.
+ * @return string                Filtered block content.
+ */
+function gutenberg_render_duotone_support( $block_content, $block ) {
+	$block_type = WP_Block_Type_Registry::get_instance()->get_registered( $block['blockName'] );
+
+	$duotone_support = false;
+	if ( $block_type && property_exists( $block_type, 'supports' ) ) {
+		$duotone_support = _wp_array_get( $block_type->supports, array( 'color', '__experimentalDuotone' ), false );
+	}
+
+	$has_duotone_attribute = isset( $block['attrs']['style']['color']['duotone'] );
+
+	if (
+		! $duotone_support ||
+		! $has_duotone_attribute
+	) {
+		return $block_content;
+	}
+
+	$duotone_colors = $block['attrs']['style']['color']['duotone'];
+
+	$duotone_values = array(
+		'r' => array(),
+		'g' => array(),
+		'b' => array(),
+	);
+	foreach ( $duotone_colors as $color_str ) {
+		$color = gutenberg_tinycolor_string_to_rgb( $color_str );
+
+		$duotone_values['r'][] = $color['r'] / 255;
+		$duotone_values['g'][] = $color['g'] / 255;
+		$duotone_values['b'][] = $color['b'] / 255;
+	}
+
+	$duotone_id = 'wp-duotone-filter-' . uniqid();
+
+	$selectors        = explode( ',', $duotone_support );
+	$selectors_scoped = array_map(
+		function ( $selector ) use ( $duotone_id ) {
+			return '.' . $duotone_id . ' ' . trim( $selector );
+		},
+		$selectors
+	);
+	$selectors_group  = implode( ', ', $selectors_scoped );
+
+	ob_start();
+
+	?>
+
+	<style>
+		<?php echo $selectors_group; ?> {
+			filter: url( <?php echo esc_url( '#' . $duotone_id ); ?> );
+		}
+	</style>
+
+	<svg
+		xmlns:xlink="http://www.w3.org/1999/xlink"
+		viewBox="0 0 0 0"
+		width="0"
+		height="0"
+		focusable="false"
+		role="none"
+		style="visibility: hidden; position: absolute; left: -9999px; overflow: hidden;"
+	>
+		<defs>
+			<filter id="<?php echo esc_attr( $duotone_id ); ?>">
+				<feColorMatrix
+					type="matrix"
+					<?php // phpcs:disable Generic.WhiteSpace.DisallowSpaceIndent ?>
+					values=".299 .587 .114 0 0
+							.299 .587 .114 0 0
+							.299 .587 .114 0 0
+							0 0 0 1 0"
+					<?php // phpcs:enable Generic.WhiteSpace.DisallowSpaceIndent ?>
+				/>
+				<feComponentTransfer color-interpolation-filters="sRGB" >
+					<feFuncR type="table" tableValues="<?php echo esc_attr( implode( ' ', $duotone_values['r'] ) ); ?>" />
+					<feFuncG type="table" tableValues="<?php echo esc_attr( implode( ' ', $duotone_values['g'] ) ); ?>" />
+					<feFuncB type="table" tableValues="<?php echo esc_attr( implode( ' ', $duotone_values['b'] ) ); ?>" />
+				</feComponentTransfer>
+			</filter>
+		</defs>
+	</svg>
+
+	<?php
+
+	$duotone = ob_get_clean();
+
+	// Like the layout hook, this assumes the hook only applies to blocks with a single wrapper.
+	$content = preg_replace(
+		'/' . preg_quote( 'class="', '/' ) . '/',
+		'class="' . $duotone_id . ' ',
+		$block_content,
+		1
+	);
+
+	return $content . $duotone;
+}
+
+// Register the block support.
+WP_Block_Supports::get_instance()->register(
+	'duotone',
+	array(
+		'register_attribute' => 'gutenberg_register_duotone_support',
+	)
+);
+add_filter( 'render_block', 'gutenberg_render_duotone_support', 10, 2 );
diff --git a/lib/class-wp-theme-json.php b/lib/class-wp-theme-json.php
index e81472dbd23b1..76e26cd1d4fff 100644
--- a/lib/class-wp-theme-json.php
+++ b/lib/class-wp-theme-json.php
@@ -108,6 +108,7 @@ class WP_Theme_JSON {
 			'gradients'      => null,
 			'link'           => null,
 			'palette'        => null,
+			'duotone'        => null,
 		),
 		'spacing'    => array(
 			'customPadding' => null,
diff --git a/lib/experimental-default-theme.json b/lib/experimental-default-theme.json
index 5eebd221e8a2c..447a768dcd5bd 100644
--- a/lib/experimental-default-theme.json
+++ b/lib/experimental-default-theme.json
@@ -126,6 +126,48 @@
 						"slug": "midnight"
 					}
 				],
+				"duotone": [
+					{
+						"name":  "Dark grayscale" ,
+						"colors": [ "#000000", "#7f7f7f" ],
+						"slug": "dark-grayscale"
+					},
+					{
+						"name":  "Grayscale" ,
+						"colors": [ "#000000", "#ffffff" ],
+						"slug": "grayscale"
+					},
+					{
+						"name":  "Purple and yellow" ,
+						"colors": [ "#8c00b7", "#fcff41" ],
+						"slug": "purple-yellow"
+					},
+					{
+						"name":  "Blue and red" ,
+						"colors": [ "#000097", "#ff4747" ],
+						"slug": "blue-red"
+					},
+					{
+						"name":  "Midnight" ,
+						"colors": [ "#000000", "#00a5ff" ],
+						"slug": "midnight"
+					},
+					{
+						"name":  "Magenta and yellow" ,
+						"colors": [ "#c7005a", "#fff278" ],
+						"slug": "magenta-yellow"
+					},
+					{
+						"name":  "Purple and green" ,
+						"colors": [ "#a60072", "#67ff66" ],
+						"slug": "purple-green"
+					},
+					{
+						"name":  "Blue and orange" ,
+						"colors": [ "#1900d8", "#ffa96b" ],
+						"slug": "blue-orange"
+					}
+				],
 				"custom": true,
 				"link": false,
 				"customGradient": true
diff --git a/lib/experimental-i18n-theme.json b/lib/experimental-i18n-theme.json
index 94889f733a331..a9dc4c429ea47 100644
--- a/lib/experimental-i18n-theme.json
+++ b/lib/experimental-i18n-theme.json
@@ -43,6 +43,11 @@
 					{
 						"name": "Gradient name"
 					}
+				],
+				"duotone": [
+					{
+						"name": "Duotone name"
+					}
 				]
 			}
 		}
diff --git a/lib/load.php b/lib/load.php
index 2deda54b6646b..dcf9539a1e526 100644
--- a/lib/load.php
+++ b/lib/load.php
@@ -126,3 +126,4 @@ function gutenberg_is_experiment_enabled( $name ) {
 require __DIR__ . '/block-supports/border.php';
 require __DIR__ . '/block-supports/layout.php';
 require __DIR__ . '/block-supports/padding.php';
+require __DIR__ . '/block-supports/duotone.php';
diff --git a/packages/block-editor/src/components/duotone-control/duotone-picker-popover.js b/packages/block-editor/src/components/duotone-control/duotone-picker-popover.js
new file mode 100644
index 0000000000000..7926cd5f977a6
--- /dev/null
+++ b/packages/block-editor/src/components/duotone-control/duotone-picker-popover.js
@@ -0,0 +1,32 @@
+/**
+ * WordPress dependencies
+ */
+import { Popover, MenuGroup, DuotonePicker } from '@wordpress/components';
+import { __ } from '@wordpress/i18n';
+
+function DuotonePickerPopover( {
+	value,
+	onChange,
+	onToggle,
+	duotonePalette,
+	colorPalette,
+} ) {
+	return (
+		<Popover
+			className="block-editor-duotone-control__popover"
+			headerTitle={ __( 'Duotone' ) }
+			onFocusOutside={ onToggle }
+		>
+			<MenuGroup label={ __( 'Duotone' ) }>
+				<DuotonePicker
+					colorPalette={ colorPalette }
+					duotonePalette={ duotonePalette }
+					value={ value }
+					onChange={ onChange }
+				/>
+			</MenuGroup>
+		</Popover>
+	);
+}
+
+export default DuotonePickerPopover;
diff --git a/packages/block-editor/src/components/duotone-control/index.js b/packages/block-editor/src/components/duotone-control/index.js
new file mode 100644
index 0000000000000..c7f597c561237
--- /dev/null
+++ b/packages/block-editor/src/components/duotone-control/index.js
@@ -0,0 +1,50 @@
+/**
+ * WordPress dependencies
+ */
+import { ToolbarButton, DuotoneSwatch } from '@wordpress/components';
+import { useState } from '@wordpress/element';
+import { __ } from '@wordpress/i18n';
+import { DOWN } from '@wordpress/keycodes';
+
+/**
+ * Internal dependencies
+ */
+import DuotonePickerPopover from './duotone-picker-popover';
+
+function DuotoneControl( { colorPalette, duotonePalette, value, onChange } ) {
+	const [ isOpen, setIsOpen ] = useState( false );
+	const onToggle = () => {
+		setIsOpen( ( prev ) => ! prev );
+	};
+	const openOnArrowDown = ( event ) => {
+		if ( ! isOpen && event.keyCode === DOWN ) {
+			event.preventDefault();
+			event.stopPropagation();
+			onToggle();
+		}
+	};
+	return (
+		<>
+			<ToolbarButton
+				showTooltip
+				onClick={ onToggle }
+				aria-haspopup="true"
+				aria-expanded={ isOpen }
+				onKeyDown={ openOnArrowDown }
+				label={ __( 'Apply duotone filter' ) }
+				icon={ <DuotoneSwatch values={ value } /> }
+			/>
+			{ isOpen && (
+				<DuotonePickerPopover
+					value={ value }
+					onChange={ onChange }
+					onToggle={ onToggle }
+					duotonePalette={ duotonePalette }
+					colorPalette={ colorPalette }
+				/>
+			) }
+		</>
+	);
+}
+
+export default DuotoneControl;
diff --git a/packages/block-editor/src/components/duotone-control/style.scss b/packages/block-editor/src/components/duotone-control/style.scss
new file mode 100644
index 0000000000000..133f0e0b8a748
--- /dev/null
+++ b/packages/block-editor/src/components/duotone-control/style.scss
@@ -0,0 +1,26 @@
+.block-editor-duotone-control__popover {
+	.components-popover__content {
+		border: $border-width solid $gray-900;
+		min-width: 214px;
+	}
+
+	.components-circular-option-picker {
+		padding: $grid-unit-15;
+	}
+
+	.components-menu-group__label {
+		padding: $grid-unit-15 $grid-unit-15 0 $grid-unit-15;
+		width: 100%;
+	}
+}
+
+.block-editor-duotone-control__popover > .components-popover__content {
+	// Matches 8 swatches in width.
+	width: 334px;
+}
+
+// Better align the popover under the swatch.
+// @todo: when the positioning for popovers gets refactored, this can presumably be removed.
+.block-editor-duotone-control__popover:not([data-y-axis="middle"][data-x-axis="right"]) > .components-popover__content {
+	margin-left: -14px;
+}
diff --git a/packages/block-editor/src/components/index.js b/packages/block-editor/src/components/index.js
index ac7471317acbe..ad27f85c085d8 100644
--- a/packages/block-editor/src/components/index.js
+++ b/packages/block-editor/src/components/index.js
@@ -36,6 +36,7 @@ export { default as ButtonBlockerAppender } from './button-block-appender';
 export { default as ColorPalette } from './color-palette';
 export { default as ColorPaletteControl } from './color-palette/control';
 export { default as ContrastChecker } from './contrast-checker';
+export { default as __experimentalDuotoneControl } from './duotone-control';
 export { default as __experimentalGradientPicker } from './gradient-picker';
 export { default as __experimentalGradientPickerControl } from './gradient-picker/control';
 export { default as __experimentalGradientPickerPanel } from './gradient-picker/panel';
diff --git a/packages/block-editor/src/hooks/duotone.js b/packages/block-editor/src/hooks/duotone.js
new file mode 100644
index 0000000000000..dd2d27a784d7b
--- /dev/null
+++ b/packages/block-editor/src/hooks/duotone.js
@@ -0,0 +1,255 @@
+/**
+ * External dependencies
+ */
+import classnames from 'classnames';
+import tinycolor from 'tinycolor2';
+
+/**
+ * WordPress dependencies
+ */
+import { getBlockSupport, hasBlockSupport } from '@wordpress/blocks';
+import { SVG } from '@wordpress/components';
+import { createHigherOrderComponent, useInstanceId } from '@wordpress/compose';
+import { addFilter } from '@wordpress/hooks';
+
+/**
+ * Internal dependencies
+ */
+import {
+	BlockControls,
+	__experimentalDuotoneControl as DuotoneControl,
+	__experimentalUseEditorFeature as useEditorFeature,
+} from '../components';
+
+/**
+ * Convert a list of colors to an object of R, G, and B values.
+ *
+ * @param {string[]} colors Array of RBG color strings.
+ *
+ * @return {Object} R, G, and B values.
+ */
+export function getValuesFromColors( colors = [] ) {
+	const values = { r: [], g: [], b: [] };
+
+	colors.forEach( ( color ) => {
+		// Access values directly to skip extra rounding that tinycolor.toRgb() does.
+		const tcolor = tinycolor( color );
+		values.r.push( tcolor._r / 255 );
+		values.g.push( tcolor._g / 255 );
+		values.b.push( tcolor._b / 255 );
+	} );
+
+	return values;
+}
+
+/**
+ * Values for the SVG `feComponentTransfer`.
+ *
+ * @typedef Values {Object}
+ * @property {number[]} r Red values.
+ * @property {number[]} g Green values.
+ * @property {number[]} b Blue values.
+ */
+
+/**
+ * SVG and stylesheet needed for rendering the duotone filter.
+ *
+ * @param  {Object} props          Duotone props.
+ * @param  {string} props.selector Selector to apply the filter to.
+ * @param  {string} props.id       Unique id for this duotone filter.
+ * @param  {Values} props.values   R, G, and B values to filter with.
+ * @return {WPElement}             Duotone element.
+ */
+function DuotoneFilter( { selector, id, values } ) {
+	const stylesheet = `
+${ selector } {
+	filter: url( #${ id } );
+}
+`;
+
+	return (
+		<>
+			<SVG
+				xmlnsXlink="http://www.w3.org/1999/xlink"
+				viewBox="0 0 0 0"
+				width="0"
+				height="0"
+				focusable="false"
+				role="none"
+				style={ {
+					visibility: 'hidden',
+					position: 'absolute',
+					left: '-9999px',
+					overflow: 'hidden',
+				} }
+			>
+				<defs>
+					<filter id={ id }>
+						<feColorMatrix
+							type="matrix"
+							// Use perceptual brightness to convert to grayscale.
+							// prettier-ignore
+							values=".299 .587 .114 0 0
+							        .299 .587 .114 0 0
+							        .299 .587 .114 0 0
+							        0 0 0 1 0"
+						/>
+						<feComponentTransfer
+							// Use sRGB instead of linearRGB to be consistent with how CSS gradients work.
+							colorInterpolationFilters="sRGB"
+						>
+							<feFuncR
+								type="table"
+								tableValues={ values.r.join( ' ' ) }
+							/>
+							<feFuncG
+								type="table"
+								tableValues={ values.g.join( ' ' ) }
+							/>
+							<feFuncB
+								type="table"
+								tableValues={ values.b.join( ' ' ) }
+							/>
+						</feComponentTransfer>
+					</filter>
+				</defs>
+			</SVG>
+			<style dangerouslySetInnerHTML={ { __html: stylesheet } } />
+		</>
+	);
+}
+
+function DuotonePanel( { attributes, setAttributes } ) {
+	const style = attributes?.style;
+	const duotone = style?.color?.duotone;
+
+	const duotonePalette = useEditorFeature( 'color.duotone' );
+	const colorPalette = useEditorFeature( 'color.palette' );
+
+	return (
+		<BlockControls group="block">
+			<DuotoneControl
+				duotonePalette={ duotonePalette }
+				colorPalette={ colorPalette }
+				value={ duotone }
+				onChange={ ( newDuotone ) => {
+					const newStyle = {
+						...style,
+						color: {
+							...style?.color,
+							duotone: newDuotone,
+						},
+					};
+					setAttributes( { style: newStyle } );
+				} }
+			/>
+		</BlockControls>
+	);
+}
+
+/**
+ * Filters registered block settings, extending attributes to include
+ * the `duotone` attribute.
+ *
+ * @param  {Object} settings Original block settings
+ * @return {Object}          Filtered block settings
+ */
+function addDuotoneAttributes( settings ) {
+	if ( ! hasBlockSupport( settings, 'color.__experimentalDuotone' ) ) {
+		return settings;
+	}
+
+	// Allow blocks to specify their own attribute definition with default
+	// values if needed.
+	if ( ! settings.attributes.style ) {
+		Object.assign( settings.attributes, {
+			style: {
+				type: 'object',
+			},
+		} );
+	}
+
+	return settings;
+}
+
+/**
+ * Override the default edit UI to include toolbar controls for duotone if the
+ * block supports duotone.
+ *
+ * @param  {Function} BlockEdit Original component
+ * @return {Function}           Wrapped component
+ */
+const withDuotoneControls = createHigherOrderComponent(
+	( BlockEdit ) => ( props ) => {
+		const hasDuotoneSupport = hasBlockSupport(
+			props.name,
+			'color.__experimentalDuotone'
+		);
+
+		return (
+			<>
+				<BlockEdit { ...props } />
+				{ hasDuotoneSupport && <DuotonePanel { ...props } /> }
+			</>
+		);
+	},
+	'withDuotoneControls'
+);
+
+/**
+ * Override the default block element to include duotone styles.
+ *
+ * @param  {Function} BlockListBlock Original component
+ * @return {Function}                Wrapped component
+ */
+const withDuotoneStyles = createHigherOrderComponent(
+	( BlockListBlock ) => ( props ) => {
+		const duotoneSupport = getBlockSupport(
+			props.name,
+			'color.__experimentalDuotone'
+		);
+		const values = props?.attributes?.style?.color?.duotone;
+
+		if ( ! duotoneSupport || ! values ) {
+			return <BlockListBlock { ...props } />;
+		}
+
+		const id = `wp-duotone-filter-${ useInstanceId( BlockListBlock ) }`;
+
+		const selectors = duotoneSupport.split( ',' );
+		const selectorsScoped = selectors.map(
+			( selector ) => `.${ id } ${ selector.trim() }`
+		);
+		const selectorsGroup = selectorsScoped.join( ', ' );
+
+		const className = classnames( props?.classname, id );
+
+		return (
+			<>
+				<DuotoneFilter
+					selector={ selectorsGroup }
+					id={ id }
+					values={ getValuesFromColors( values ) }
+				/>
+				<BlockListBlock { ...props } className={ className } />
+			</>
+		);
+	},
+	'withDuotoneStyles'
+);
+
+addFilter(
+	'blocks.registerBlockType',
+	'core/editor/duotone/add-attributes',
+	addDuotoneAttributes
+);
+addFilter(
+	'editor.BlockEdit',
+	'core/editor/duotone/with-editor-controls',
+	withDuotoneControls
+);
+addFilter(
+	'editor.BlockListBlock',
+	'core/editor/duotone/with-styles',
+	withDuotoneStyles
+);
diff --git a/packages/block-editor/src/hooks/index.js b/packages/block-editor/src/hooks/index.js
index c087e994ba9eb..6bf7db445f70b 100644
--- a/packages/block-editor/src/hooks/index.js
+++ b/packages/block-editor/src/hooks/index.js
@@ -7,5 +7,6 @@ import './custom-class-name';
 import './generated-class-name';
 import './style';
 import './color';
+import './duotone';
 import './font-size';
 import './layout';
diff --git a/packages/block-editor/src/style.scss b/packages/block-editor/src/style.scss
index f80eeefd3be42..f0b7bcaa36342 100644
--- a/packages/block-editor/src/style.scss
+++ b/packages/block-editor/src/style.scss
@@ -31,6 +31,7 @@
 @import "./components/colors-gradients/style.scss";
 @import "./components/contrast-checker/style.scss";
 @import "./components/default-block-appender/style.scss";
+@import "./components/duotone-control/style.scss";
 @import "./components/font-appearance-control/style.scss";
 @import "./components/justify-content-control/style.scss";
 @import "./components/link-control/style.scss";
diff --git a/packages/block-library/src/cover/block.json b/packages/block-library/src/cover/block.json
index b0b2d58bde2aa..676fb581c2b95 100644
--- a/packages/block-library/src/cover/block.json
+++ b/packages/block-library/src/cover/block.json
@@ -56,6 +56,11 @@
 		"html": false,
 		"spacing": {
 			"padding": true
+		},
+		"color": {
+			"__experimentalDuotone": "> .wp-block-cover__image-background, > .wp-block-cover__video-background",
+			"text": false,
+			"background": false
 		}
 	},
 	"editorStyle": "wp-block-cover-editor",
diff --git a/packages/block-library/src/cover/transforms.js b/packages/block-library/src/cover/transforms.js
index 85b340af2e9bb..bb6af0ac319c1 100644
--- a/packages/block-library/src/cover/transforms.js
+++ b/packages/block-library/src/cover/transforms.js
@@ -13,7 +13,7 @@ const transforms = {
 		{
 			type: 'block',
 			blocks: [ 'core/image' ],
-			transform: ( { caption, url, align, id, anchor } ) =>
+			transform: ( { caption, url, align, id, anchor, duotone } ) =>
 				createBlock(
 					'core/cover',
 					{
@@ -21,6 +21,7 @@ const transforms = {
 						align,
 						id,
 						anchor,
+						duotone,
 					},
 					[
 						createBlock( 'core/paragraph', {
@@ -76,13 +77,14 @@ const transforms = {
 					! customGradient
 				);
 			},
-			transform: ( { title, url, align, id, anchor } ) =>
+			transform: ( { title, url, align, id, anchor, duotone } ) =>
 				createBlock( 'core/image', {
 					caption: title,
 					url,
 					align,
 					id,
 					anchor,
+					duotone,
 				} ),
 		},
 		{
diff --git a/packages/block-library/src/image/block.json b/packages/block-library/src/image/block.json
index 3952230ded6a3..6b9fb6443a236 100644
--- a/packages/block-library/src/image/block.json
+++ b/packages/block-library/src/image/block.json
@@ -72,6 +72,11 @@
 	},
 	"supports": {
 		"anchor": true,
+		"color": {
+			"__experimentalDuotone": "img",
+			"text": false,
+			"background": false
+		},
 		"__experimentalBorder": {
 			"radius": true
 		}
diff --git a/packages/block-library/src/image/index.php b/packages/block-library/src/image/index.php
new file mode 100644
index 0000000000000..8743baebf60fc
--- /dev/null
+++ b/packages/block-library/src/image/index.php
@@ -0,0 +1,45 @@
+<?php
+/**
+ * Server-side rendering of the `core/image` block.
+ *
+ * @package WordPress
+ */
+
+/**
+ * Supports `duotone` attribute server side for `core/image`.
+ *
+ * @param array  $attributes The block attributes.
+ * @param string $content HTML content of the block.
+ *
+ * @return string Rendered HTML of the referenced block.
+ */
+function render_block_core_image( $attributes, $content ) {
+	if ( ! isset( $attributes['style']['color']['duotone'] ) ) {
+		return $content;
+	}
+
+	$id        = $attributes['style']['color']['duotone']['id'];
+	$values    = $attributes['style']['color']['duotone']['values'];
+	$selectors = array(
+		'div.wp-block-image .' . $id . ' img',
+		'figure.wp-block-image.' . $id . ' img',
+	);
+	$selector  = implode( ', ', $selectors );
+
+	$duotone = gutenberg_render_duotone_filter( $selector, $id, $values );
+
+	return $content . $duotone;
+}
+
+/**
+ * Registers the `core/image` block.
+ */
+function register_block_core_image() {
+	register_block_type_from_metadata(
+		__DIR__ . '/image',
+		array(
+			'render_callback' => 'render_block_core_image',
+		)
+	);
+}
+add_action( 'init', 'register_block_core_image' );
diff --git a/packages/block-library/src/media-text/block.json b/packages/block-library/src/media-text/block.json
index 0e175cf04bd53..c63b8289e34d5 100644
--- a/packages/block-library/src/media-text/block.json
+++ b/packages/block-library/src/media-text/block.json
@@ -86,6 +86,7 @@
 		"align": [ "wide", "full" ],
 		"html": false,
 		"color": {
+			"duotone": "img, video",
 			"gradients": true,
 			"link": true
 		}
diff --git a/packages/block-library/src/media-text/transforms.js b/packages/block-library/src/media-text/transforms.js
index 0851b6d550421..0990bbc479741 100644
--- a/packages/block-library/src/media-text/transforms.js
+++ b/packages/block-library/src/media-text/transforms.js
@@ -8,24 +8,26 @@ const transforms = {
 		{
 			type: 'block',
 			blocks: [ 'core/image' ],
-			transform: ( { alt, url, id, anchor } ) =>
+			transform: ( { alt, url, id, anchor, duotone } ) =>
 				createBlock( 'core/media-text', {
 					mediaAlt: alt,
 					mediaId: id,
 					mediaUrl: url,
 					mediaType: 'image',
 					anchor,
+					duotone,
 				} ),
 		},
 		{
 			type: 'block',
 			blocks: [ 'core/video' ],
-			transform: ( { src, id, anchor } ) =>
+			transform: ( { src, id, anchor, duotone } ) =>
 				createBlock( 'core/media-text', {
 					mediaId: id,
 					mediaUrl: src,
 					mediaType: 'video',
 					anchor,
+					duotone,
 				} ),
 		},
 	],
@@ -36,12 +38,13 @@ const transforms = {
 			isMatch: ( { mediaType, mediaUrl } ) => {
 				return ! mediaUrl || mediaType === 'image';
 			},
-			transform: ( { mediaAlt, mediaId, mediaUrl, anchor } ) => {
+			transform: ( { mediaAlt, mediaId, mediaUrl, anchor, duotone } ) => {
 				return createBlock( 'core/image', {
 					alt: mediaAlt,
 					id: mediaId,
 					url: mediaUrl,
 					anchor,
+					duotone,
 				} );
 			},
 		},
@@ -51,11 +54,12 @@ const transforms = {
 			isMatch: ( { mediaType, mediaUrl } ) => {
 				return ! mediaUrl || mediaType === 'video';
 			},
-			transform: ( { mediaId, mediaUrl, anchor } ) => {
+			transform: ( { mediaId, mediaUrl, anchor, duotone } ) => {
 				return createBlock( 'core/video', {
 					id: mediaId,
 					src: mediaUrl,
 					anchor,
+					duotone,
 				} );
 			},
 		},
diff --git a/packages/block-library/src/video/block.json b/packages/block-library/src/video/block.json
index 9f8b569d239b2..a3cee6eabc410 100644
--- a/packages/block-library/src/video/block.json
+++ b/packages/block-library/src/video/block.json
@@ -71,7 +71,12 @@
 	},
 	"supports": {
 		"anchor": true,
-		"align": true
+		"align": true,
+		"color": {
+			"duotone": "video",
+			"text": false,
+			"background": false
+		}
 	},
 	"editorStyle": "wp-block-video-editor",
 	"style": "wp-block-video"
diff --git a/packages/components/src/color-list-picker/index.js b/packages/components/src/color-list-picker/index.js
new file mode 100644
index 0000000000000..7550cb8b12b1c
--- /dev/null
+++ b/packages/components/src/color-list-picker/index.js
@@ -0,0 +1,56 @@
+/**
+ * WordPress dependencies
+ */
+import { useState } from '@wordpress/element';
+
+/**
+ * Internal dependencies
+ */
+import Button from '../button';
+import ColorPalette from '../color-palette';
+import Swatch from '../swatch';
+
+function ColorOption( { label, value, colors, onChange } ) {
+	const [ isOpen, setIsOpen ] = useState( false );
+	return (
+		<>
+			<Button
+				className="components-color-list-picker__swatch-button"
+				icon={ <Swatch fill={ value } /> }
+				onClick={ () => setIsOpen( ( prev ) => ! prev ) }
+			>
+				{ label }
+			</Button>
+			{ isOpen && (
+				<ColorPalette
+					colors={ colors }
+					value={ value }
+					clearable={ false }
+					onChange={ onChange }
+				/>
+			) }
+		</>
+	);
+}
+
+function ColorListPicker( { colors, labels, value = [], onChange } ) {
+	return (
+		<div className="components-color-list-picker">
+			{ labels.map( ( label, index ) => (
+				<ColorOption
+					key={ index }
+					label={ label }
+					value={ value[ index ] }
+					colors={ colors }
+					onChange={ ( newColor ) => {
+						const newColors = value.slice();
+						newColors[ index ] = newColor;
+						onChange( newColors );
+					} }
+				/>
+			) ) }
+		</div>
+	);
+}
+
+export default ColorListPicker;
diff --git a/packages/components/src/color-list-picker/style.scss b/packages/components/src/color-list-picker/style.scss
new file mode 100644
index 0000000000000..09a8e7348066c
--- /dev/null
+++ b/packages/components/src/color-list-picker/style.scss
@@ -0,0 +1,4 @@
+.components-color-list-picker,
+.components-color-list-picker__swatch-button {
+	width: 100%;
+}
diff --git a/packages/components/src/custom-gradient-bar/control-points.js b/packages/components/src/custom-gradient-bar/control-points.js
index d8d5ec16c2fa7..5bec42a2f2ae6 100644
--- a/packages/components/src/custom-gradient-bar/control-points.js
+++ b/packages/components/src/custom-gradient-bar/control-points.js
@@ -109,6 +109,8 @@ function ControlPointButton( {
 }
 
 function ControlPoints( {
+	disableRemove,
+	disableAlpha,
 	gradientPickerDomRef,
 	ignoreMarkerPosition,
 	value: controlPoints,
@@ -223,6 +225,7 @@ function ControlPoints( {
 					renderContent={ ( { onClose } ) => (
 						<>
 							<ColorPicker
+								disableAlpha={ disableAlpha }
 								color={ point.color }
 								onChangeComplete={ ( { color } ) => {
 									onChange(
@@ -234,21 +237,23 @@ function ControlPoints( {
 									);
 								} }
 							/>
-							<Button
-								className="components-custom-gradient-picker__remove-control-point"
-								onClick={ () => {
-									onChange(
-										removeControlPoint(
-											controlPoints,
-											index
-										)
-									);
-									onClose();
-								} }
-								isLink
-							>
-								{ __( 'Remove Control Point' ) }
-							</Button>
+							{ ! disableRemove && (
+								<Button
+									className="components-custom-gradient-picker__remove-control-point"
+									onClick={ () => {
+										onChange(
+											removeControlPoint(
+												controlPoints,
+												index
+											)
+										);
+										onClose();
+									} }
+									isLink
+								>
+									{ __( 'Remove Control Point' ) }
+								</Button>
+							) }
 						</>
 					) }
 					popoverProps={ COLOR_POPOVER_PROPS }
@@ -264,6 +269,7 @@ function InsertPoint( {
 	onOpenInserter,
 	onCloseInserter,
 	insertPosition,
+	disableAlpha,
 } ) {
 	const [ alreadyInsertedPoint, setAlreadyInsertedPoint ] = useState( false );
 	return (
@@ -297,6 +303,7 @@ function InsertPoint( {
 			) }
 			renderContent={ () => (
 				<ColorPicker
+					disableAlpha={ disableAlpha }
 					onChangeComplete={ ( { color } ) => {
 						if ( ! alreadyInsertedPoint ) {
 							onChange(
diff --git a/packages/components/src/custom-gradient-bar/index.js b/packages/components/src/custom-gradient-bar/index.js
index bd8b1922cdf6e..823e3d00992a3 100644
--- a/packages/components/src/custom-gradient-bar/index.js
+++ b/packages/components/src/custom-gradient-bar/index.js
@@ -76,6 +76,8 @@ export default function CustomGradientBar( {
 	hasGradient,
 	value: controlPoints,
 	onChange,
+	disableInserter = false,
+	disableAlpha = false,
 } ) {
 	const gradientPickerDomRef = useRef();
 
@@ -129,24 +131,28 @@ export default function CustomGradientBar( {
 			onMouseLeave={ onMouseLeave }
 		>
 			<div className="components-custom-gradient-picker__markers-container">
-				{ ( isMovingInserter || isInsertingControlPoint ) && (
-					<ControlPoints.InsertPoint
-						insertPosition={ gradientBarState.insertPosition }
-						value={ controlPoints }
-						onChange={ onChange }
-						onOpenInserter={ () => {
-							gradientBarStateDispatch( {
-								type: 'OPEN_INSERTER',
-							} );
-						} }
-						onCloseInserter={ () => {
-							gradientBarStateDispatch( {
-								type: 'CLOSE_INSERTER',
-							} );
-						} }
-					/>
-				) }
+				{ ! disableInserter &&
+					( isMovingInserter || isInsertingControlPoint ) && (
+						<ControlPoints.InsertPoint
+							disableAlpha={ disableAlpha }
+							insertPosition={ gradientBarState.insertPosition }
+							value={ controlPoints }
+							onChange={ onChange }
+							onOpenInserter={ () => {
+								gradientBarStateDispatch( {
+									type: 'OPEN_INSERTER',
+								} );
+							} }
+							onCloseInserter={ () => {
+								gradientBarStateDispatch( {
+									type: 'CLOSE_INSERTER',
+								} );
+							} }
+						/>
+					) }
 				<ControlPoints
+					disableAlpha={ disableAlpha }
+					disableRemove={ disableInserter }
 					gradientPickerDomRef={ gradientPickerDomRef }
 					ignoreMarkerPosition={
 						isInsertingControlPoint
diff --git a/packages/components/src/duotone-picker/custom-duotone-bar.js b/packages/components/src/duotone-picker/custom-duotone-bar.js
new file mode 100644
index 0000000000000..1a898273e392e
--- /dev/null
+++ b/packages/components/src/duotone-picker/custom-duotone-bar.js
@@ -0,0 +1,32 @@
+/**
+ * Internal dependencies
+ */
+import CustomGradientBar from '../custom-gradient-bar';
+
+import {
+	getColorStopsFromColors,
+	getGradientFromCSSColors,
+	getColorsFromColorStops,
+} from './utils';
+
+const PLACEHOLDER_VALUES = [ '#333', '#CCC' ];
+
+export default function CustomDuotoneBar( { value, onChange } ) {
+	const hasGradient = !! value;
+	const values = hasGradient ? value : PLACEHOLDER_VALUES;
+	const background = getGradientFromCSSColors( values );
+	const controlPoints = getColorStopsFromColors( values );
+	return (
+		<CustomGradientBar
+			disableInserter
+			disableAlpha
+			background={ background }
+			hasGradient={ hasGradient }
+			value={ controlPoints }
+			onChange={ ( newColorStops ) => {
+				const newValue = getColorsFromColorStops( newColorStops );
+				onChange( newValue );
+			} }
+		/>
+	);
+}
diff --git a/packages/components/src/duotone-picker/duotone-picker.js b/packages/components/src/duotone-picker/duotone-picker.js
new file mode 100644
index 0000000000000..fb15f12162559
--- /dev/null
+++ b/packages/components/src/duotone-picker/duotone-picker.js
@@ -0,0 +1,92 @@
+/**
+ * External dependencies
+ */
+import { isEqual } from 'lodash';
+
+/**
+ * WordPress dependencies
+ */
+import { useMemo } from '@wordpress/element';
+import { __, sprintf } from '@wordpress/i18n';
+
+/**
+ * Internal dependencies
+ */
+import ColorListPicker from '../color-list-picker';
+import CircularOptionPicker from '../circular-option-picker';
+
+import CustomDuotoneBar from './custom-duotone-bar';
+import { getDefaultColors, getGradientFromCSSColors } from './utils';
+
+function DuotonePicker( { colorPalette, duotonePalette, value, onChange } ) {
+	const [ defaultDark, defaultLight ] = useMemo(
+		() => getDefaultColors( colorPalette ),
+		[ colorPalette ]
+	);
+	return (
+		<CircularOptionPicker
+			options={ duotonePalette.map( ( { colors, slug, name } ) => {
+				const style = {
+					background: getGradientFromCSSColors( colors, '135deg' ),
+					color: 'transparent',
+				};
+				const tooltipText =
+					name ??
+					sprintf(
+						// translators: %s: duotone code e.g: "dark-grayscale" or "7f7f7f-ffffff".
+						__( 'Duotone code: %s' ),
+						slug
+					);
+				const label = name
+					? sprintf(
+							// translators: %s: The name of the option e.g: "Dark grayscale".
+							__( 'Duotone: %s' ),
+							name
+					  )
+					: tooltipText;
+				const isSelected = isEqual( colors, value );
+
+				return (
+					<CircularOptionPicker.Option
+						key={ slug }
+						value={ colors }
+						isSelected={ isSelected }
+						aria-label={ label }
+						tooltipText={ tooltipText }
+						style={ style }
+						onClick={ () => {
+							onChange( isSelected ? undefined : colors );
+						} }
+					/>
+				);
+			} ) }
+			actions={
+				<CircularOptionPicker.ButtonAction
+					onClick={ () => onChange( undefined ) }
+				>
+					{ __( 'Clear' ) }
+				</CircularOptionPicker.ButtonAction>
+			}
+		>
+			<CustomDuotoneBar value={ value } onChange={ onChange } />
+			<ColorListPicker
+				labels={ [ __( 'Shadows' ), __( 'Highlights' ) ] }
+				colors={ colorPalette }
+				value={ value }
+				onChange={ ( newColors ) => {
+					if ( ! newColors[ 0 ] ) {
+						newColors[ 0 ] = defaultDark;
+					}
+					if ( ! newColors[ 1 ] ) {
+						newColors[ 1 ] = defaultLight;
+					}
+					const newValue =
+						newColors.length >= 2 ? newColors : undefined;
+					onChange( newValue );
+				} }
+			/>
+		</CircularOptionPicker>
+	);
+}
+
+export default DuotonePicker;
diff --git a/packages/components/src/duotone-picker/duotone-swatch.js b/packages/components/src/duotone-picker/duotone-swatch.js
new file mode 100644
index 0000000000000..1ab35b53034c7
--- /dev/null
+++ b/packages/components/src/duotone-picker/duotone-swatch.js
@@ -0,0 +1,16 @@
+/**
+ * Internal dependencies
+ */
+import Swatch from '../swatch';
+
+import { getGradientFromCSSColors } from './utils';
+
+function DuotoneSwatch( { values } ) {
+	return (
+		<Swatch
+			fill={ values && getGradientFromCSSColors( values, '135deg' ) }
+		/>
+	);
+}
+
+export default DuotoneSwatch;
diff --git a/packages/components/src/duotone-picker/index.js b/packages/components/src/duotone-picker/index.js
new file mode 100644
index 0000000000000..0043b43902900
--- /dev/null
+++ b/packages/components/src/duotone-picker/index.js
@@ -0,0 +1,2 @@
+export { default as DuotonePicker } from './duotone-picker';
+export { default as DuotoneSwatch } from './duotone-swatch';
diff --git a/packages/components/src/duotone-picker/utils.js b/packages/components/src/duotone-picker/utils.js
new file mode 100644
index 0000000000000..72c607072e8c6
--- /dev/null
+++ b/packages/components/src/duotone-picker/utils.js
@@ -0,0 +1,84 @@
+/**
+ * External dependencies
+ */
+import tinycolor from 'tinycolor2';
+
+/**
+ * Object representation for a color.
+ *
+ * @typedef {Object} RGBColor
+ * @property {number} r Red component of the color in the range [0,1].
+ * @property {number} g Green component of the color in the range [0,1].
+ * @property {number} b Blue component of the color in the range [0,1].
+ */
+
+/**
+ * Calculate the brightest and darkest values from a color palette.
+ *
+ * @param {Object[]} palette Color palette for the theme.
+ *
+ * @return {string[]} Tuple of the darkest color and brightest color.
+ */
+export function getDefaultColors( palette ) {
+	// A default dark and light color are required.
+	if ( ! palette || palette.length < 2 ) return [ '#000', '#fff' ];
+
+	return palette
+		.map( ( { color } ) => ( {
+			color,
+			brightness: tinycolor( color ).getBrightness() / 255,
+		} ) )
+		.reduce(
+			( [ min, max ], current ) => {
+				return [
+					current.brightness <= min.brightness ? current : min,
+					current.brightness >= max.brightness ? current : max,
+				];
+			},
+			[ { brightness: 1 }, { brightness: 0 } ]
+		)
+		.map( ( { color } ) => color );
+}
+
+/**
+ * Generate a duotone gradient from a list of colors.
+ *
+ * @param {string[]} colors CSS color strings.
+ * @param {string}   angle  CSS gradient angle.
+ *
+ * @return {string} CSS gradient string for the duotone swatch.
+ */
+export function getGradientFromCSSColors( colors = [], angle = '90deg' ) {
+	const l = 100 / colors.length;
+
+	const stops = colors
+		.map( ( c, i ) => `${ c } ${ i * l }%, ${ c } ${ ( i + 1 ) * l }%` )
+		.join( ', ' );
+
+	return `linear-gradient( ${ angle }, ${ stops } )`;
+}
+
+/**
+ * Convert a color array to an array of color stops.
+ *
+ * @param {string[]} colors CSS colors array
+ *
+ * @return {Object[]} Color stop information.
+ */
+export function getColorStopsFromColors( colors ) {
+	return colors.map( ( color, i ) => ( {
+		position: ( i * 100 ) / ( colors.length - 1 ),
+		color,
+	} ) );
+}
+
+/**
+ * Convert a color stop array to an array colors.
+ *
+ * @param {Object[]} colorStops Color stop information.
+ *
+ * @return {string[]} CSS colors array.
+ */
+export function getColorsFromColorStops( colorStops = [] ) {
+	return colorStops.map( ( { color } ) => color );
+}
diff --git a/packages/components/src/index.js b/packages/components/src/index.js
index 0c67e9330f035..efbfcce172359 100644
--- a/packages/components/src/index.js
+++ b/packages/components/src/index.js
@@ -59,6 +59,7 @@ export {
 } from './drop-zone/provider';
 export { default as Dropdown } from './dropdown';
 export { default as DropdownMenu } from './dropdown-menu';
+export { DuotoneSwatch, DuotonePicker } from './duotone-picker';
 export { default as ExternalLink } from './external-link';
 export { default as Flex } from './flex';
 export { default as FlexBlock } from './flex/block';
diff --git a/packages/components/src/style.scss b/packages/components/src/style.scss
index a7b92c1192b13..13c2049b894bf 100644
--- a/packages/components/src/style.scss
+++ b/packages/components/src/style.scss
@@ -8,6 +8,7 @@
 @import "./color-indicator/style.scss";
 @import "./color-picker/style.scss";
 @import "./combobox-control/style.scss";
+@import "./color-list-picker/style.scss";
 @import "./custom-gradient-picker/style.scss";
 @import "./custom-select-control/style.scss";
 @import "./date-time/style.scss";
@@ -36,6 +37,7 @@
 @import "./scroll-lock/style.scss";
 @import "./select-control/style.scss";
 @import "./snackbar/style.scss";
+@import "./swatch/style.scss";
 @import "./tab-panel/style.scss";
 @import "./text-control/style.scss";
 @import "./tip/style.scss";
diff --git a/packages/components/src/swatch/index.js b/packages/components/src/swatch/index.js
new file mode 100644
index 0000000000000..1d86ace0ec773
--- /dev/null
+++ b/packages/components/src/swatch/index.js
@@ -0,0 +1,19 @@
+/**
+ * WordPress dependencies
+ */
+import { swatch } from '@wordpress/icons';
+
+/**
+ * Internal dependencies
+ */
+import Icon from '../icon';
+
+function Swatch( { fill } ) {
+	return fill ? (
+		<span className="components-swatch" style={ { background: fill } } />
+	) : (
+		<Icon icon={ swatch } />
+	);
+}
+
+export default Swatch;
diff --git a/packages/components/src/swatch/style.scss b/packages/components/src/swatch/style.scss
new file mode 100644
index 0000000000000..b18b361f39d65
--- /dev/null
+++ b/packages/components/src/swatch/style.scss
@@ -0,0 +1,21 @@
+.components-swatch {
+	width: 18px;
+	height: 18px;
+	border-radius: 50%;
+	color: transparent;
+	background: transparent;
+
+	// Regular border doesn't seem to work in the toolbar button, but pseudo-selector border does.
+	&::after {
+		content: "";
+		display: block;
+		width: 100%;
+		height: 100%;
+		border: $border-width solid rgba(0, 0, 0, 0.2);
+		border-radius: 50%;
+	}
+}
+
+.components-button.has-icon.has-text .components-swatch {
+	margin-right: $grid-unit;
+}
diff --git a/packages/icons/src/index.js b/packages/icons/src/index.js
index 3fa3853b61568..dfb71e79e6d6c 100644
--- a/packages/icons/src/index.js
+++ b/packages/icons/src/index.js
@@ -187,6 +187,7 @@ export { default as shipping } from './library/shipping';
 export { default as stretchWide } from './library/stretch-wide';
 export { default as subscript } from './library/subscript';
 export { default as superscript } from './library/superscript';
+export { default as swatch } from './library/swatch';
 export { default as tableColumnAfter } from './library/table-column-after';
 export { default as tableColumnBefore } from './library/table-column-before';
 export { default as tableColumnDelete } from './library/table-column-delete';
diff --git a/packages/icons/src/library/swatch.js b/packages/icons/src/library/swatch.js
new file mode 100644
index 0000000000000..1d9a63e84838e
--- /dev/null
+++ b/packages/icons/src/library/swatch.js
@@ -0,0 +1,12 @@
+/**
+ * WordPress dependencies
+ */
+import { Path, SVG } from '@wordpress/primitives';
+
+const swatch = (
+	<SVG xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24">
+		<Path d="M5 17.7c.4.5.8.9 1.2 1.2l1.1-1.4c-.4-.3-.7-.6-1-1L5 17.7zM5 6.3l1.4 1.1c.3-.4.6-.7 1-1L6.3 5c-.5.4-.9.8-1.3 1.3zm.1 7.8l-1.7.5c.2.6.4 1.1.7 1.6l1.5-.8c-.2-.4-.4-.8-.5-1.3zM4.8 12v-.7L3 11.1v1.8l1.7-.2c.1-.2.1-.5.1-.7zm3 7.9c.5.3 1.1.5 1.6.7l.5-1.7c-.5-.1-.9-.3-1.3-.5l-.8 1.5zM19 6.3c-.4-.5-.8-.9-1.2-1.2l-1.1 1.4c.4.3.7.6 1 1L19 6.3zm-.1 3.6l1.7-.5c-.2-.6-.4-1.1-.7-1.6l-1.5.8c.2.4.4.8.5 1.3zM5.6 8.6l-1.5-.8c-.3.5-.5 1-.7 1.6l1.7.5c.1-.5.3-.9.5-1.3zm2.2-4.5l.8 1.5c.4-.2.8-.4 1.3-.5l-.5-1.7c-.6.2-1.1.4-1.6.7zm8.8 13.5l1.1 1.4c.5-.4.9-.8 1.2-1.2l-1.4-1.1c-.2.3-.5.6-.9.9zm1.8-2.2l1.5.8c.3-.5.5-1.1.7-1.6l-1.7-.5c-.1.5-.3.9-.5 1.3zm2.6-4.3l-1.7.2v1.4l1.7.2V12v-.9zM11.1 3l.2 1.7h1.4l.2-1.7h-1.8zm3 2.1c.5.1.9.3 1.3.5l.8-1.5c-.5-.3-1.1-.5-1.6-.7l-.5 1.7zM12 19.2h-.7l-.2 1.8h1.8l-.2-1.7c-.2-.1-.5-.1-.7-.1zm2.1-.3l.5 1.7c.6-.2 1.1-.4 1.6-.7l-.8-1.5c-.4.2-.8.4-1.3.5z" />
+	</SVG>
+);
+
+export default swatch;
diff --git a/phpunit/class-wp-theme-json-resolver-test.php b/phpunit/class-wp-theme-json-resolver-test.php
index 9e9d298ab6666..f840f07f4a164 100644
--- a/phpunit/class-wp-theme-json-resolver-test.php
+++ b/phpunit/class-wp-theme-json-resolver-test.php
@@ -84,6 +84,11 @@ function test_fields_are_extracted() {
 				'key'     => 'name',
 				'context' => 'Gradient name',
 			),
+			array(
+				'path'    => array( 'settings', '*', 'color', 'duotone' ),
+				'key'     => 'name',
+				'context' => 'Duotone name',
+			),
 			array(
 				'path'    => array( 'customTemplates' ),
 				'key'     => 'title',