diff --git a/packages/components/CHANGELOG.md b/packages/components/CHANGELOG.md
index a12b09a153309e..7d3fd67a4984ff 100644
--- a/packages/components/CHANGELOG.md
+++ b/packages/components/CHANGELOG.md
@@ -5,6 +5,7 @@
 ### Internal
 
 -   Refactor `FocalPointPicker` to function component ([#39168](https://github.com/WordPress/gutenberg/pull/39168)).
+-   `Guide`: use `code` instead of `keyCode` for keyboard events ([#43604](https://github.com/WordPress/gutenberg/pull/43604/)).
 
 ## 20.0.0 (2022-08-24)
 
diff --git a/packages/components/src/guide/index.js b/packages/components/src/guide/index.js
index 91e4b0d147ff18..4669f13471801b 100644
--- a/packages/components/src/guide/index.js
+++ b/packages/components/src/guide/index.js
@@ -9,7 +9,6 @@ import classnames from 'classnames';
 import { useState, useEffect, Children, useRef } from '@wordpress/element';
 import deprecated from '@wordpress/deprecated';
 import { __ } from '@wordpress/i18n';
-import { LEFT, RIGHT } from '@wordpress/keycodes';
 import { focus } from '@wordpress/dom';
 
 /**
@@ -76,10 +75,14 @@ export default function Guide( {
 			contentLabel={ contentLabel }
 			onRequestClose={ onFinish }
 			onKeyDown={ ( event ) => {
-				if ( event.keyCode === LEFT ) {
+				if ( event.code === 'ArrowLeft' ) {
 					goBack();
-				} else if ( event.keyCode === RIGHT ) {
+					// Do not scroll the modal's contents.
+					event.preventDefault();
+				} else if ( event.code === 'ArrowRight' ) {
 					goForward();
+					// Do not scroll the modal's contents.
+					event.preventDefault();
 				}
 			} }
 			ref={ guideContainer }
diff --git a/packages/components/src/guide/test/index.js b/packages/components/src/guide/test/index.js
index bd36752959ff69..852c09ed280887 100644
--- a/packages/components/src/guide/test/index.js
+++ b/packages/components/src/guide/test/index.js
@@ -1,7 +1,7 @@
 /**
  * External dependencies
  */
-import { render, screen } from '@testing-library/react';
+import { render, screen, within } from '@testing-library/react';
 import userEvent from '@testing-library/user-event';
 
 /**
@@ -118,4 +118,141 @@ describe( 'Guide', () => {
 
 		expect( onFinish ).toHaveBeenCalled();
 	} );
+
+	describe( 'page navigation', () => {
+		it( 'renders an empty list when there are no pages', () => {
+			render( <Guide pages={ [] } /> );
+			expect(
+				screen.queryByRole( 'list', {
+					name: 'Guide controls',
+				} )
+			).not.toBeInTheDocument();
+			expect(
+				screen.queryByRole( 'button', {
+					name: /page \d of \d/i,
+				} )
+			).not.toBeInTheDocument();
+		} );
+
+		it( 'renders a button for each page', () => {
+			render(
+				<Guide
+					pages={ [
+						{ content: <p>Page 1</p> },
+						{ content: <p>Page 2</p> },
+						{ content: <p>Page 3</p> },
+						{ content: <p>Page 4</p> },
+					] }
+				/>
+			);
+			const listContainer = screen.getByRole( 'list', {
+				name: 'Guide controls',
+			} );
+			expect(
+				within( listContainer ).getAllByRole( 'button', {
+					name: /page \d of \d/i,
+				} )
+			).toHaveLength( 4 );
+		} );
+
+		it( 'sets the current page when a button is clicked', async () => {
+			const user = userEvent.setup( {
+				advanceTimers: jest.advanceTimersByTime,
+			} );
+
+			render(
+				<Guide
+					pages={ [
+						{ content: <p>Page 1</p> },
+						{ content: <p>Page 2</p> },
+						{ content: <p>Page 3</p> },
+					] }
+				/>
+			);
+
+			expect( screen.getByText( 'Page 1' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.click(
+				screen.getByRole( 'button', { name: 'Page 2 of 3' } )
+			);
+
+			expect( screen.getByText( 'Page 2' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.click(
+				screen.getByRole( 'button', { name: 'Page 3 of 3' } )
+			);
+
+			expect( screen.getByText( 'Page 3' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+
+			await user.click(
+				screen.getByRole( 'button', { name: 'Page 1 of 3' } )
+			);
+
+			expect( screen.getByText( 'Page 1' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+		} );
+
+		it( 'allows navigating through the pages with the left and right arrows', async () => {
+			const user = userEvent.setup( {
+				advanceTimers: jest.advanceTimersByTime,
+			} );
+
+			render(
+				<Guide
+					pages={ [
+						{ content: <p>Page 1</p> },
+						{ content: <p>Page 2</p> },
+						{ content: <p>Page 3</p> },
+					] }
+				/>
+			);
+
+			expect( screen.getByText( 'Page 1' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowLeft]' );
+
+			expect( screen.getByText( 'Page 1' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowRight]' );
+
+			expect( screen.getByText( 'Page 2' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowRight]' );
+
+			expect( screen.getByText( 'Page 3' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowRight]' );
+
+			expect( screen.getByText( 'Page 3' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowLeft]' );
+
+			expect( screen.getByText( 'Page 2' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 1' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+
+			await user.keyboard( '[ArrowLeft]' );
+
+			expect( screen.getByText( 'Page 1' ) ).toBeVisible();
+			expect( screen.queryByText( 'Page 2' ) ).not.toBeInTheDocument();
+			expect( screen.queryByText( 'Page 3' ) ).not.toBeInTheDocument();
+		} );
+	} );
 } );
diff --git a/packages/components/src/guide/test/page-control.js b/packages/components/src/guide/test/page-control.js
deleted file mode 100644
index caeb3dd005476a..00000000000000
--- a/packages/components/src/guide/test/page-control.js
+++ /dev/null
@@ -1,40 +0,0 @@
-/**
- * External dependencies
- */
-import { render, screen } from '@testing-library/react';
-import userEvent from '@testing-library/user-event';
-
-/**
- * Internal dependencies
- */
-import PageControl from '../page-control';
-
-describe( 'PageControl', () => {
-	it( 'renders an empty list when there are no pages', () => {
-		render( <PageControl currentPage={ 0 } numberOfPages={ 0 } /> );
-		expect( screen.queryByRole( 'button' ) ).not.toBeInTheDocument();
-	} );
-
-	it( 'renders a button for each page', () => {
-		render( <PageControl currentPage={ 0 } numberOfPages={ 5 } /> );
-		expect( screen.getAllByRole( 'button' ) ).toHaveLength( 5 );
-	} );
-
-	it( 'sets the current page when a button is clicked', async () => {
-		const user = userEvent.setup( {
-			advanceTimers: jest.advanceTimersByTime,
-		} );
-		const setCurrentPage = jest.fn();
-		render(
-			<PageControl
-				currentPage={ 0 }
-				numberOfPages={ 2 }
-				setCurrentPage={ setCurrentPage }
-			/>
-		);
-
-		await user.click( screen.getAllByRole( 'button' )[ 1 ] );
-
-		expect( setCurrentPage ).toHaveBeenCalledWith( 1 );
-	} );
-} );