diff --git a/.github/workflows/build-wheels.yml b/.github/workflows/build-wheels.yml
index dcc3ca8263..07f3708085 100644
--- a/.github/workflows/build-wheels.yml
+++ b/.github/workflows/build-wheels.yml
@@ -18,6 +18,9 @@ on:
 
 env:
   SETUPTOOLS_SCM_PRETEND_VERSION_FOR_TILEDB: ${{ inputs.version }}
+  S3_BUCKET: ${{ vars.S3_BUCKET }}
+  TILEDB_NAMESPACE: ${{ vars.TILEDB_NAMESPACE }}
+  TILEDB_TOKEN: ${{ secrets.TILEDB_TOKEN }}
 
 jobs:
   build_wheels:
@@ -46,7 +49,7 @@ jobs:
         uses: pypa/cibuildwheel@v2.18.1
         env:
           CIBW_BUILD_VERBOSITY: 3
-          CIBW_ENVIRONMENT_PASS_LINUX: SETUPTOOLS_SCM_PRETEND_VERSION_FOR_TILEDB
+          CIBW_ENVIRONMENT_PASS_LINUX: SETUPTOOLS_SCM_PRETEND_VERSION_FOR_TILEDB S3_BUCKET TILEDB_TOKEN TILEDB_NAMESPACE
           CIBW_ENVIRONMENT_MACOS: >
             CC=clang
             CXX=clang++
@@ -155,6 +158,6 @@ jobs:
         with:
           repository-url: https://test.pypi.org/legacy/
 
-      # - name: Upload to pypi
-      #   if: startsWith(github.ref, 'refs/tags/')
-      #   uses: pypa/gh-action-pypi-publish@release/v1
+      - name: Upload to pypi
+        if: startsWith(github.ref, 'refs/tags/')
+        uses: pypa/gh-action-pypi-publish@release/v1
diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index c497ebf92b..7bb1af3b77 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -6,6 +6,11 @@ concurrency:
   group: ${{ github.head_ref || github.run_id }}
   cancel-in-progress: true
 
+env:
+  S3_BUCKET: ${{ vars.S3_BUCKET }}
+  TILEDB_NAMESPACE: ${{ vars.TILEDB_NAMESPACE }}
+  TILEDB_TOKEN: ${{ secrets.TILEDB_TOKEN }}
+
 jobs:
   build:
     runs-on: ${{ matrix.os }}
diff --git a/tiledb/tests/test_cloud.py b/tiledb/tests/test_cloud.py
new file mode 100644
index 0000000000..c09795556c
--- /dev/null
+++ b/tiledb/tests/test_cloud.py
@@ -0,0 +1,71 @@
+import datetime
+import os
+import random
+import string
+
+import numpy as np
+import pytest
+
+import tiledb
+from tiledb.tests.common import DiskTestCase
+
+tiledb_token = os.getenv("TILEDB_TOKEN")
+tiledb_namespace = os.getenv("TILEDB_NAMESPACE")
+s3_bucket = os.getenv("S3_BUCKET")
+
+
+@pytest.mark.skipif(
+    not os.getenv("CI") and tiledb_token is None,
+    reason="No token was provided in a non-CI environment. Please set the TILEDB_TOKEN environment variable to run this test.",
+)
+class CloudTest(DiskTestCase):
+    def test_save_and_open_array_from_cloud(self):
+        config = tiledb.Config({"rest.token": tiledb_token})
+        ctx = tiledb.Ctx(config=config)
+
+        # Useful to include the datetime in the array name to handle multiple consecutive runs of the test.
+        # Random letters are added to the end to ensure that conflicts are avoided, especially in CI environments where multiple tests may run in parallel.
+        array_name = (
+            datetime.datetime.now().strftime("%Y-%m-%d-%H-%M-%S")
+            + "-"
+            + "".join(random.choice(string.ascii_letters) for _ in range(5))
+        )
+        uri = f"tiledb://{tiledb_namespace}/s3://{s3_bucket}/{array_name}"
+
+        with tiledb.from_numpy(uri, np.random.rand(3, 2), ctx=ctx) as T:
+            self.assertTrue(tiledb.array_exists(uri, ctx=ctx))
+            self.assertTrue(
+                T.schema
+                == tiledb.ArraySchema(
+                    domain=tiledb.Domain(
+                        tiledb.Dim(
+                            name="__dim_0",
+                            domain=(0, 2),
+                            tile=3,
+                            dtype="uint64",
+                            filters=tiledb.FilterList([tiledb.ZstdFilter(level=-1)]),
+                        ),
+                        tiledb.Dim(
+                            name="__dim_1",
+                            domain=(0, 1),
+                            tile=2,
+                            dtype="uint64",
+                            filters=tiledb.FilterList([tiledb.ZstdFilter(level=-1)]),
+                        ),
+                    ),
+                    attrs=[
+                        tiledb.Attr(
+                            name="",
+                            dtype="float64",
+                            var=False,
+                            nullable=False,
+                            enum_label=None,
+                        ),
+                    ],
+                    cell_order="row-major",
+                    tile_order="row-major",
+                    sparse=False,
+                )
+            )
+
+        tiledb.Array.delete_array(uri, ctx=ctx)