GPR curation for Transport reactions (6)

[JHL-452b]

Current behavior:

40 genes are discovered to be uncorrelated with their corresponding reactions in Transport reactions.

Gene	UniProtID	Reaction	GPR	Correlation	Manually check
ENSG00000151012	Q9UPY5	MAR05719: cysteine + Na+ + threonine --> cysteine + Na+ + threonine	ENSG00000103064 or ENSG00000105281 or ENSG00000115902 or ENSG00000151012	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000151012 functions primarily as an antiporter that mediates the exchange of extracellular anionic L-cystine and intracellular L-glutamate, and it also facilitates the import of L-kynurenine and N-acetyl-L-cysteine. The provided reaction "cysteine + Na+ + threonine --> cysteine + Na+ + threonine" does not involve any of these substrates or exchanges, nor does it align with the catalytic activities described for the gene, which involve different substrates and exchange mechanisms.	No
ENSG00000103064	Q92536	MAR05723: alanine + leucine + Na+ --> alanine + leucine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter, primarily involved in the exchange of L-arginine and other amino acids such as L-leucine, L-glutamine, L-histidine, and L-cysteine, often coupled with sodium ions. The specified reaction involving alanine and leucine with sodium ions does not match any of the listed substrates or products for this gene¡¯s antiporter activity, indicating no relevance.	No
ENSG00000103064	Q92536	MAR05725: leucine + Na+ + serine --> leucine + Na+ + serine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions as an antiporter, facilitating the exchange of cationic amino acids such as L-arginine with neutral amino acids like L-leucine, L-glutamine, and others. However, the reaction provided involves leucine, Na+, and serine, which does not match any of the specific antiport activities attributed to the gene's protein product. The gene's protein does not mediate a reaction involving serine as a substrate or product, making the gene irrelevant to the given reaction.	No
ENSG00000103064	Q92536	MAR05731: leucine + Na+ + proline --> leucine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 functions primarily in the antiport of cationic amino acids like L-arginine in exchange for neutral amino acids such as L-leucine and others, often in a sodium-dependent manner. The reaction described involves the exchange of leucine, sodium, and proline, which is not consistent with the exchanges facilitated by the gene product. Therefore, the gene and the reaction are unrelated.	No
ENSG00000103064	Q92536	MAR05733: leucine + Na+ + valine --> leucine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that primarily functions as an antiporter to exchange L-arginine with various neutral amino acids such as L-leucine, L-glutamine, and L-isoleucine along with sodium ions. The catalytic activities listed involve the exchange of L-arginine with different amino acids and sodium ions in a 1:1 stoichiometry. However, the reaction provided describes an exchange involving leucine, sodium ions, and valine, which is not listed among the catalytic activities of the gene product. Therefore, the gene does not match the reaction provided.	No
ENSG00000103064	Q92536	MAR05735: homoserine + leucine + Na+ --> homoserine + leucine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions primarily as an antiporter involved in the exchange of specific amino acids such as L-arginine, L-lysine, L-leucine, L-glutamine, and others, often involving sodium ions. The reaction provided, "homoserine + leucine + Na+ --> homoserine + leucine + Na+," does not involve any of the specific amino acids exchanged by the protein encoded by this gene. Furthermore, the described gene activities and catalytic functions do not match the reaction, indicating no relevance.	No
ENSG00000103064	Q92536	MAR05738: alanine + Na+ + proline --> alanine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter exchanging cationic amino acids such as L-arginine with neutral amino acids including L-leucine, L-glutamine, and others, often involving sodium ions. However, the provided reaction pertains to the exchange of alanine, sodium ion, and proline, which does not involve L-arginine or the specific amino acids mentioned in the gene's function. Therefore, the gene's annotated functions do not align with the described reaction.	No
ENSG00000103064	Q92536	MAR05740: Na+ + proline + serine --> Na+ + proline + serine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 codes for a protein that functions primarily as an antiporter for cationic amino acids, exchanging L-arginine with various neutral amino acids and sodium ions. The described catalytic activities do not include the reaction "Na+ + proline + serine --> Na+ + proline + serine." Therefore, based on the provided annotation, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05745: cysteine + Na+ + proline --> cysteine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The provided gene, ENSG00000103064, encodes a protein that primarily functions as a cationic amino acid antiporter, facilitating the exchange of L-arginine with various other amino acids such as L-lysine, L-leucine, L-glutamine, and others either in a sodium-dependent or independent manner. The reaction provided involves cysteine, sodium ion, and proline, which does not align with any of the catalytic activities or amino acid exchanges described for this gene, thus indicating the gene is not relevant to the given reaction.	No
ENSG00000103064	Q92536	MAR05746: leucine + Na+ + proline --> leucine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter for various cationic and neutral amino acids, such as L-arginine, L-leucine, L-glutamine, isoleucine, L-lysine, L-histidine, L-cysteine, L-methionine, and glycine betaine. However, the specified reaction "leucine + Na+ + proline --> leucine + Na+ + proline" does not involve any of the amino acids that this antiporter is known to transport. Thus, the catalytic activities of the gene product do not correspond with the reaction provided.	No
ENSG00000103064	Q92536	MAR05747: asparagine + Na+ + proline --> asparagine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 functions as an antiporter involved in the exchange of cationic amino acids (like L-arginine) with neutral amino acids (like L-leucine, L-glutamine, etc.), and sometimes with sodium ions. The mentioned reactions catalyzed by the gene do not involve the conversion of asparagine and proline, which is specified in the provided reaction. This discrepancy indicates no direct relevance between the gene and the provided reaction.	No
ENSG00000103064	Q92536	MAR05748: Na+ + proline + valine --> Na+ + proline + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 is involved in the exchange of cationic amino acids such as L-arginine with neutral amino acids like L-leucine, L-glutamine, and isoleucine, among others. Its function also includes the regulation of nitric oxide synthesis and ammonia-dependent processes in astrocytes. However, the provided reaction involves the transport of proline and valine, which are not mentioned in the gene's annotated functions or catalytic activities. Hence, the gene does not relate to the specified reaction.	No
ENSG00000103064	Q92536	MAR05750: homoserine + Na+ + proline --> homoserine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions primarily as a transport protein exchanging various amino acids such as L-arginine, L-lysine, L-leucine, L-glutamine, and others, in conjunction with sodium ions, across cellular membranes. The provided reaction, which involves the interchange of homoserine, sodium, and proline, does not align with the specific amino acid transport activities described for this gene. Therefore, the gene is not relevant to the reaction provided.	No
ENSG00000103064	Q92536	MAR05751: isoleucine + Na+ + proline --> isoleucine + Na+ + proline	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The provided gene ENSG00000103064 encodes a protein that functions primarily as an antiporter for various amino acids including L-arginine, L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine in exchange for sodium ions. However, the reaction presented involves isoleucine, Na+, and proline, which do not match the specific amino acids transported by the protein encoded by this gene. Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05753: alanine + asparagine + Na+ --> alanine + asparagine + Na+	ENSG00000103064 or ENSG00000105281	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 is involved in the exchange of cationic and neutral amino acids such as L-arginine, L-leucine, L-glutamine, L-histidine, L-cysteine, L-methionine, and L-lysine in the presence or absence of sodium ions. The provided reaction, "alanine + asparagine + Na+ --> alanine + asparagine + Na+," does not involve the amino acids that the gene is responsible for transporting. Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05754: asparagine + glutamine + Na+ --> asparagine + glutamine + Na+	ENSG00000103064 or ENSG00000105281	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions primarily as an antiporter involved in the exchange of cationic and neutral amino acids across cell membranes, such as L-arginine, L-leucine, L-glutamine, and others, often in the presence of sodium ions. The annotated catalytic activities include various exchanges involving L-arginine and other amino acids. However, the reaction provided (asparagine + glutamine + Na+ --> asparagine + glutamine + Na+) does not involve L-arginine or any of the amino acids or exchange mechanisms described for the gene's function, indicating no relevance to the provided reaction.	No
ENSG00000103064	Q92536	MAR05756: asparagine + methionine + Na+ --> asparagine + methionine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 functions primarily in the antiporter exchange of cationic amino acids such as L-arginine for neutral amino acids like L-leucine, L-glutamine, and others, often involving sodium ions. The catalytic activities described in the gene annotation involve the exchange of L-arginine with other amino acids (e.g., L-lysine, L-leucine, L-glutamine, etc.), with some reactions being sodium-dependent. However, the reaction provided involves asparagine and methionine with sodium ions, which is not covered by any of the catalytic activities associated with the gene ENSG00000103064. Thus, the gene is not relevant to the provided reaction.	No
ENSG00000103064	Q92536	MAR05758: asparagine + Na+ + phenylalanine --> asparagine + Na+ + phenylalanine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein functioning as an antiporter for the exchange of cationic and neutral amino acids coupled with sodium ions, specifically involving amino acids such as L-arginine, L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine. The reactions catalyzed by the protein revolve around the exchange of these specific amino acids and do not include phenylalanine, which is required in the provided reaction "asparagine + Na+ + phenylalanine --> asparagine + Na+ + phenylalanine". Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05760: asparagine + cysteine + Na+ --> asparagine + cysteine + Na+	ENSG00000103064 or ENSG00000105281	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 describes a protein that functions as an antiporter involved in the transport of cationic and neutral amino acids such as L-arginine, L-leucine, and others, along with sodium ions. The described gene catalyzes multiple specific amino acid exchange reactions, but none of these involve the direct reaction of asparagine and cysteine with sodium ions as mentioned in the provided reaction. Thus, the gene is not relevant to the reaction provided.	No
ENSG00000103064	Q92536	MAR05761: asparagine + leucine + Na+ --> asparagine + leucine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that primarily functions in the transport of cationic and neutral amino acids, including L-arginine, L-lysine, L-leucine, L-glutamine, and others, typically coupled with sodium ions (Na+) in exchange processes. These exchanges are specific and do not involve asparagine. The provided reaction describes an exchange or transport involving asparagine, leucine, and sodium ions, which is not mentioned in the gene's annotated functions or catalytic activities. Therefore, the gene's function does not align with the described reaction.	No
ENSG00000103064	Q92536	MAR05763: asparagine + Na+ + valine --> asparagine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 is associated with transporting cationic amino acids such as L-arginine in exchange with neutral amino acids like L-leucine, L-glutamine, and others, often in the presence of sodium ions. It does not involve the transport or reaction with asparagine and valine, as mentioned in the provided reaction. Therefore, based on the functions and catalytic activities detailed in the annotation, the gene does not relate to the reaction described.	No
ENSG00000103064	Q92536	MAR05765: asparagine + homoserine + Na+ --> asparagine + homoserine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 is involved in the transport of cationic and neutral amino acids, such as L-arginine, L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine, along with sodium ions, in an antiporter mechanism. However, the reaction mentioned involves asparagine, homoserine, and sodium ions, which are not substrates associated with the gene's annotated function. Therefore, there is no direct involvement of this gene in the specified reaction.	No
ENSG00000103064	Q92536	MAR05769: glutamine + Na+ + valine --> glutamine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter mainly involved in the exchange of cationic amino acids like L-arginine and neutral amino acids such as L-leucine, L-glutamine, and L-isoleucine, with sodium ions in some cases. The protein's catalytic activities described in the annotation do not match the given reaction, which involves glutamine, sodium, and valine. Therefore, the gene is not related to the reaction involving glutamine, sodium, and valine.	No
ENSG00000103064	Q92536	MAR05770: Na+ + serine + valine --> Na+ + serine + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 functions primarily as an antiporter, exchanging cationic amino acids like L-arginine with neutral amino acids such as L-leucine, L-glutamine, L-isoleucine, and others, plus sodium ions. However, the given reaction involves the exchange of Na+ with serine and valine, which are not mentioned as substrates or products in the catalytic activity of the gene. Thus, there is no relevance between the gene's function and the provided reaction.	No
ENSG00000103064	Q92536	MAR05771: methionine + Na+ + valine --> methionine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions primarily as an antiporter, facilitating the exchange of cationic amino acids like L-arginine with neutral amino acids such as L-leucine, in the presence of sodium ions. However, the reaction provided involves methionine and valine with sodium ions, which does not align with the annotated functions and catalytic activities of this gene product. Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05774: Na+ + tyrosine + valine --> Na+ + tyrosine + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 codes for a protein that functions as an antiporter, specifically involved in the exchange of cationic amino acids such as L-arginine with neutral amino acids like L-leucine, L-glutamine, and L-isoleucine, among others, often in a sodium-dependent manner. The reaction provided, however, involves the exchange of Na+ with tyrosine and valine, which are not mentioned in the catalytic activities or function of the gene product. Thus, the gene's annotated functions and catalytic activities do not align with the reaction provided.	No
ENSG00000103064	Q92536	MAR05775: cysteine + Na+ + valine --> cysteine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 is involved in the transport of L-arginine and various other amino acids in an antiporter manner, often requiring sodium ions for exchange. The reaction described (cysteine + Na+ + valine --> cysteine + Na+ + valine) does not match any of the catalytic activities or functions associated with this gene, as it neither specifies L-arginine nor involves the typical antiporter exchange mechanism described in the gene annotations.	No
ENSG00000103064	Q92536	MAR05777: Na+ + proline + valine --> Na+ + proline + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions as an antiporter specifically involved in the exchange of cationic amino acids like L-arginine, L-lysine, and various neutral amino acids such as L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine, often in the presence of sodium ions. The provided reaction involves the exchange of proline and valine, which are not mentioned as substrates for the gene's antiporter activity. Therefore, the gene's annotated functions do not align with the reaction involving proline and valine.	No
ENSG00000103064	Q92536	MAR05778: asparagine + Na+ + valine --> asparagine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions mainly as an antiporter for cationic and neutral amino acids, such as L-arginine, L-leucine, L-glutamine, L-lysine, and others, often in exchange with sodium ions. However, the reaction provided involves the exchange of asparagine, sodium, and valine, which are not mentioned as substrates or products of the catalytic activities associated with this gene. Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05779: Na+ + threonine + valine --> Na+ + threonine + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein involved in the antiport exchange of cationic and neutral amino acids, particularly L-arginine, in various combinations with L-leucine, L-lysine, L-glutamine, L-histidine, L-cysteine, and L-methionine, often in the presence of sodium ions. However, the reaction provided mentions only the exchange involving threonine and valine with Na+, which is not among the catalytic activities described for the protein encoded by this gene. Hence, there is no direct relevance or overlap in functionality.	No
ENSG00000103064	Q92536	MAR05780: homoserine + Na+ + valine --> homoserine + Na+ + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that primarily functions as an antiporter, exchanging cationic and neutral amino acids such as L-arginine, L-leucine, L-glutamine, and others, often in a sodium-dependent manner. The specific catalytic activities described in the annotation involve exchanges of amino acids like L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine with L-arginine. The provided reaction, "homoserine + Na+ + valine --> homoserine + Na+ + valine," does not involve L-arginine or any of the amino acids mentioned in the gene's function. Additionally, the mechanism of the provided reaction does not align with the antiporter activity described for the gene product. Therefore, the gene is not relevant to the reaction provided.	No
ENSG00000103064	Q92536	MAR05783: alanine + Na+ + threonine --> alanine + Na+ + threonine	ENSG00000103064 or ENSG00000105281 or ENSG00000115902	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes for a protein that functions primarily as an antiporter, facilitating the exchange of L-arginine with various other amino acids (e.g., L-lysine, L-leucine, L-glutamine) along with sodium ions. This particular antiport process does not involve the substrates alanine and threonine as described in the reaction "alanine + Na+ + threonine --> alanine + Na+ + threonine." Therefore, the catalytic activities associated with the gene's encoded protein do not align with the reaction specified, demonstrating no relevance between the gene and the provided reaction.	No
ENSG00000103064	Q92536	MAR05789: Na+ + threonine + tyrosine --> Na+ + threonine + tyrosine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter involved in the transport of cationic amino acids such as L-arginine in exchange with neutral amino acids like L-leucine, L-glutamine, and L-isoleucine. It also has catalytic activity involving the exchange of L-arginine with amino acids like L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine. However, the reaction provided involves Na+, threonine, and tyrosine, which are not substrates or products of the catalytic activities mentioned for this gene. Therefore, the gene is not related to the given reaction.	No
ENSG00000103064	Q92536	MAR05790: cysteine + Na+ + threonine --> cysteine + Na+ + threonine	ENSG00000103064 or ENSG00000105281 or ENSG00000115902	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter, exchanging various amino acids such as L-arginine with neutral amino acids (e.g., L-leucine, L-glutamine) and sodium ions. The provided reaction involves cysteine, Na+, and threonine, which are not substrates or products associated with the known functions and catalytic activities of the gene's encoded protein. Therefore, the gene does not relate to the specified reaction.	No
ENSG00000103064	Q92536	MAR05792: Na+ + proline + threonine --> Na+ + proline + threonine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions as an antiporter, primarily involved in the exchange of cationic amino acids such as L-arginine with neutral amino acids like L-leucine, L-glutamine, and isoleucine, and sodium ions. The reactions catalyzed by this protein involve amino acids such as L-lysine, L-leucine, L-glutamine, L-histidine, L-cysteine, and L-methionine in combination with L-arginine. In contrast, the provided reaction involves the exchange of Na+, proline, and threonine, which are not part of the typical substrates or products associated with the gene ENSG00000103064. Thus, the gene does not align with or affect the given reaction.	No
ENSG00000103064	Q92536	MAR05793: asparagine + Na+ + threonine --> asparagine + Na+ + threonine	ENSG00000103064 or ENSG00000105281	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions as an antiporter involved in the exchange of cationic amino acids like L-arginine with neutral amino acids such as L-leucine and L-glutamine, along with sodium ions. However, the reaction provided describes the transport of asparagine and threonine with sodium ions, which is not among the activities catalyzed by the product of this gene according to the given annotations.	No
ENSG00000103064	Q92536	MAR05794: Na+ + threonine + valine --> Na+ + threonine + valine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that functions primarily as an antiporter, exchanging cationic and neutral amino acids along with sodium ions, such as L-arginine with L-leucine, L-glutamine, and L-histidine, among others. The provided reaction involves Na+ with threonine and valine, which are not listed as substrates or exchange partners for the antiporter activity of the protein encoded by ENSG00000103064 based on the given annotations.	No
ENSG00000103064	Q92536	MAR05795: homoserine + Na+ + threonine --> homoserine + Na+ + threonine	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes for a protein that functions as an antiporter, specifically involved in the exchange of L-arginine with various other amino acids like L-lysine, L-leucine, L-glutamine, and several others, often in a sodium-dependent manner. The annotated functions of this gene include the transport of amino acids and participation in nitric oxide synthesis. However, the reaction provided involves the transformation of homoserine and threonine in the presence of sodium ions, which is unrelated to the functions of the gene ENSG00000103064, as there is no mention of homoserine or threonine being substrates for the encoded transporter.	No
ENSG00000103064	Q92536	MAR05797: glycine + homoserine + Na+ --> glycine + homoserine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation: The gene ENSG00000103064 encodes a protein that primarily functions as an antiporter, facilitating the exchange of L-arginine with other amino acids such as L-leucine, L-glutamine, L-lysine, L-histidine, L-cysteine, and L-methionine, often in a sodium-dependent or independent manner. The listed catalytic activities associated with this gene involve various amino acids and sodium ions, but there is no mention of the reaction involving glycine and homoserine as specified in the reaction provided. Therefore, the gene and the reaction are not related.	No
ENSG00000103064	Q92536	MAR05798: alanine + homoserine + Na+ --> alanine + homoserine + Na+	ENSG00000103064	Pending No, the gene is not relevant to the reaction provided. Analysis and explanation. The gene ENSG00000103064 encodes a protein that functions as an antiporter exchanging cationic amino acids like L-arginine with neutral amino acids such as L-leucine, L-glutamine, and isoleucine, plus sodium ions. Its catalytic activities involve the exchange of L-arginine with other amino acids in a sodium-dependent or independent manner. However, the reaction described involves alanine and homoserine with sodium ions, which does not match the specific amino acid exchanges facilitated by the protein encoded by the gene ENSG00000103064. Therefore, the gene is not relevant to the reaction provided.	No

[hhl-24]

All of these seem fine to me.