From 7b36c5c278d8a2968123d82edc832e23d493dd90 Mon Sep 17 00:00:00 2001 From: Jiahao Luo <67491919+JHL-452b@users.noreply.github.com> Date: Tue, 31 Dec 2024 09:18:12 +0800 Subject: [PATCH] fix: GPR curation for transport reactions (9) --- model/Human-GEM.yml | 62 ++++++--------------------------------------- 1 file changed, 8 insertions(+), 54 deletions(-) diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml index 8e34d936..007b9568 100644 --- a/model/Human-GEM.yml +++ b/model/Human-GEM.yml @@ -156797,7 +156797,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -156831,7 +156830,6 @@ - MAM02896e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -156933,7 +156931,6 @@ - MAM02770e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -156967,7 +156964,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157001,7 +156997,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157052,7 +157047,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157086,7 +157080,6 @@ - MAM02896e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157171,7 +157164,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157188,7 +157180,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157205,7 +157196,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157222,7 +157212,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157256,7 +157245,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157273,7 +157261,6 @@ - MAM02770e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157307,7 +157294,7 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281" + - gene_reaction_rule: "ENSG00000105281" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157324,7 +157311,7 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281" + - gene_reaction_rule: "ENSG00000105281" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157358,7 +157345,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157392,7 +157378,6 @@ - MAM02724e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157426,7 +157411,7 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281" + - gene_reaction_rule: "ENSG00000105281" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157443,7 +157428,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157477,7 +157461,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157511,7 +157494,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157579,7 +157561,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157596,7 +157577,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157613,7 +157593,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157664,7 +157643,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157681,7 +157659,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157715,7 +157692,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157732,7 +157708,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157749,7 +157724,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157766,7 +157740,6 @@ - MAM03135e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157817,7 +157790,7 @@ - MAM02993e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281 or ENSG00000115902" + - gene_reaction_rule: "ENSG00000105281 or ENSG00000115902" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157919,7 +157892,6 @@ - MAM03101e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157936,7 +157908,7 @@ - MAM02993e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281 or ENSG00000115902" + - gene_reaction_rule: "ENSG00000105281 or ENSG00000115902" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157970,7 +157942,6 @@ - MAM02993e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -157987,7 +157958,7 @@ - MAM02993e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000105281" + - gene_reaction_rule: "ENSG00000105281" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158004,7 +157975,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158021,7 +157991,6 @@ - MAM02993e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158055,7 +158024,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158072,7 +158040,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158106,7 +158073,6 @@ - MAM02896e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158157,7 +158123,6 @@ - MAM02724e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158174,7 +158139,6 @@ - MAM03101e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158191,7 +158155,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158208,7 +158171,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158242,7 +158204,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158259,7 +158220,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158327,7 +158287,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158378,7 +158337,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158480,7 +158438,6 @@ - MAM02770e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -158514,7 +158471,6 @@ - MAM03135e: 1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -159398,7 +159354,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -159568,7 +159523,6 @@ - MAM02519e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064" - rxnFrom: "HMRdatabase" - references: "PMID:14770309;PMID:14770310" - subsystem: @@ -161138,7 +161092,7 @@ - MAM03157e: -1 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000104635 or ENSG00000110911 or ENSG00000138821 or ENSG00000139540 or ENSG00000141424 or ENSG00000141873 or ENSG00000143570 or ENSG00000147804 or ENSG00000165794 or ENSG00000196950" + - gene_reaction_rule: "ENSG00000104635 or ENSG00000110911 or ENSG00000138821 or ENSG00000139540 or ENSG00000141424 or ENSG00000141873 or ENSG00000143570 or ENSG00000147804 or ENSG00000165794 or ENSG00000196950" - rxnFrom: "HMRdatabase" - references: "PMID:14530970" - subsystem: @@ -161224,7 +161178,7 @@ - MAM02519e: -3 - lower_bound: 0 - upper_bound: 1000 - - gene_reaction_rule: "ENSG00000103064 or ENSG00000158296" + - gene_reaction_rule: "ENSG00000158296" - rxnFrom: "HMRdatabase" - references: "PMID:12739168;PMID:12915942" - subsystem: