From 95b977aede9067e1fc309ad103320650c596cfd2 Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Tue, 16 May 2023 14:24:40 +0200 Subject: [PATCH 1/4] data: update human-fruitfly OG pairs - downloaded from Alliance of Genome Resources v5.4.0 --- data/human2FruitflyOrthologs.tsv | 217 +++++++++++++++---------------- 1 file changed, 106 insertions(+), 111 deletions(-) diff --git a/data/human2FruitflyOrthologs.tsv b/data/human2FruitflyOrthologs.tsv index c6348ce..a0df099 100644 --- a/data/human2FruitflyOrthologs.tsv +++ b/data/human2FruitflyOrthologs.tsv @@ -18,7 +18,7 @@ HGNC:14235 AASDHPPT FB:FBgn0052099 CG32099 Yes Yes 9 9 HGNC:17366 AASS FB:FBgn0286198 LKRSDH Yes Yes 9 9 HGNC:19235 AATF FB:FBgn0031851 Aatf Yes Yes 7 9 HGNC:23 ABAT FB:FBgn0036927 Gabat Yes Yes 9 9 -HGNC:14637 ABCA12 FB:FBgn0083956 CG34120 Yes Yes 4 9 +HGNC:14637 ABCA12 FB:FBgn0083956 ldd Yes Yes 4 9 HGNC:14638 ABCA13 FB:FBgn0031169 CG1494 Yes Yes 2 9 HGNC:14638 ABCA13 FB:FBgn0031171 CG1801 Yes Yes 2 9 HGNC:14638 ABCA13 FB:FBgn0051213 CG31213 Yes Yes 2 9 @@ -134,7 +134,7 @@ HGNC:89 ACADM FB:FBgn0035811 Mcad Yes Yes 8 9 HGNC:90 ACADS FB:FBgn0038742 Arc42 Yes Yes 9 9 HGNC:90 ACADS FB:FBgn0037999 CG4860 No Yes 3 9 HGNC:91 ACADSB FB:FBgn0036824 CG3902 Yes Yes 9 9 -HGNC:92 ACADVL FB:FBgn0034432 CG7461 Yes Yes 9 9 +HGNC:92 ACADVL FB:FBgn0034432 Acadvl Yes Yes 9 9 HGNC:16467 ACAP1 FB:FBgn0039056 CenB1A Yes Yes 9 9 HGNC:16469 ACAP2 FB:FBgn0039056 CenB1A Yes No 8 9 HGNC:16754 ACAP3 FB:FBgn0039056 CenB1A Yes Yes 9 9 @@ -219,6 +219,7 @@ HGNC:160 ACTL6B FB:FBgn0025716 Bap55 Yes Yes 9 9 HGNC:161 ACTL7A FB:FBgn0011743 Arp53D Yes Yes 2 9 HGNC:162 ACTL7B FB:FBgn0011743 Arp53D Yes Yes 2 9 HGNC:28494 ACTL9 FB:FBgn0011743 Arp53D Yes Yes 2 9 +HGNC:24758 ACTMAP FB:FBgn0053108 CG33108 Yes Yes 8 9 HGNC:163 ACTN1 FB:FBgn0000667 Actn Yes Yes 9 9 HGNC:164 ACTN2 FB:FBgn0000667 Actn Yes No 8 9 HGNC:165 ACTN3 FB:FBgn0000667 Actn Yes No 8 9 @@ -985,7 +986,7 @@ HGNC:24007 ATAD3B FB:FBgn0287225 bor Yes No 8 9 HGNC:32151 ATAD3C FB:FBgn0287225 bor Yes No 4 9 HGNC:25752 ATAD5 FB:FBgn0036574 elg1 Yes Yes 6 9 HGNC:21186 ATAT1 FB:FBgn0035989 Atat Yes Yes 7 9 -HGNC:21186 ATAT1 FB:FBgn0031082 CG17003 No Yes 5 9 +HGNC:21186 ATAT1 FB:FBgn0031082 lky No Yes 5 9 HGNC:779 ATCAY FB:FBgn0035488 CG11593 Yes Yes 7 9 HGNC:782 ATE1 FB:FBgn0025720 Ate1 Yes Yes 9 9 HGNC:783 ATF1 FB:FBgn0265784 CrebB Yes Yes 6 9 @@ -1246,7 +1247,7 @@ HGNC:948 BAIAP3 FB:FBgn0266719 stac No Yes 3 9 HGNC:948 BAIAP3 FB:FBgn0035756 unc-13-4A Yes Yes 8 9 HGNC:17397 BANF1 FB:FBgn0031977 baf Yes Yes 6 9 HGNC:18233 BANK1 FB:FBgn0020299 stumps Yes No 4 9 -HGNC:950 BAP1 FB:FBgn0262166 calypso Yes Yes 8 9 +HGNC:950 BAP1 FB:FBgn0262166 caly Yes Yes 8 9 HGNC:953 BARHL1 FB:FBgn0011758 B-H1 Yes Yes 6 9 HGNC:954 BARHL2 FB:FBgn0011758 B-H1 Yes Yes 6 9 HGNC:954 BARHL2 FB:FBgn0004854 B-H2 Yes Yes 6 9 @@ -1277,8 +1278,8 @@ HGNC:27050 BCDIN3D FB:FBgn0035537 CG11342 Yes Yes 9 9 HGNC:983 BCHE FB:FBgn0000024 Ace Yes Yes 6 9 HGNC:986 BCKDHA FB:FBgn0037709 CG8199 Yes Yes 8 9 HGNC:987 BCKDHB FB:FBgn0039993 CG17691 Yes Yes 9 9 -HGNC:13221 BCL11A FB:FBgn0029939 CG9650 Yes Yes 7 9 -HGNC:13222 BCL11B FB:FBgn0029939 CG9650 Yes Yes 7 9 +HGNC:13221 BCL11A FB:FBgn0029939 Cph Yes Yes 7 9 +HGNC:13222 BCL11B FB:FBgn0029939 Cph Yes Yes 7 9 HGNC:1004 BCL7A FB:FBgn0026149 BCL7-like Yes No 6 9 HGNC:1005 BCL7B FB:FBgn0026149 BCL7-like Yes Yes 8 9 HGNC:1006 BCL7C FB:FBgn0026149 BCL7-like Yes Yes 8 9 @@ -1467,18 +1468,15 @@ HGNC:30204 C11orf54 FB:FBgn0035189 CG9119 Yes Yes 9 9 HGNC:30204 C11orf54 FB:FBgn0063667 meep Yes Yes 9 9 HGNC:1184 C12orf4 FB:FBgn0039589 CG9986 Yes Yes 9 9 HGNC:29521 C12orf57 FB:FBgn0031403 CG15387 Yes Yes 8 9 -HGNC:34450 C12orf73 FB:FBgn0259204 CG42308 Yes Yes 5 9 HGNC:20270 C14orf119 FB:FBgn0037739 CG12948 Yes Yes 4 9 HGNC:28443 C15orf40 FB:FBgn0035415 CG14966 Yes Yes 7 9 HGNC:34453 C15orf61 FB:FBgn0083984 CG34148 Yes Yes 9 9 HGNC:28687 C16orf89 FB:FBgn0034069 CG8401 Yes Yes 2 9 -HGNC:27558 C16orf91 FB:FBgn0050373 CG30373 Yes Yes 2 9 HGNC:28737 C17orf49 FB:FBgn0052831 CG33695 Yes Yes 7 9 HGNC:31690 C18orf32 FB:FBgn0028746 CG18508 Yes Yes 5 9 HGNC:25443 C19orf12 FB:FBgn0023530 CG3740 Yes Yes 8 9 HGNC:25443 C19orf12 FB:FBgn0037562 Nazo No Yes 5 9 HGNC:26723 C19orf47 FB:FBgn0032488 CG16812 Yes Yes 6 9 -HGNC:24758 C19orf54 FB:FBgn0053108 CG33108 Yes Yes 8 9 HGNC:29911 C1D FB:FBgn0030711 Rrp47 Yes Yes 5 9 HGNC:24337 C1GALT1 FB:FBgn0032078 C1GalTA Yes Yes 7 9 HGNC:24337 C1GALT1 FB:FBgn0031469 CG18558 No Yes 4 9 @@ -1708,7 +1706,7 @@ HGNC:28163 CCDC28B FB:FBgn0031395 CG10874 Yes Yes 7 9 HGNC:25079 CCDC34 FB:FBgn0031722 CG14011 Yes Yes 2 9 HGNC:25079 CCDC34 FB:FBgn0031724 CG18266 Yes Yes 2 9 HGNC:25079 CCDC34 FB:FBgn0031723 CG7251 Yes Yes 2 9 -HGNC:25244 CCDC39 FB:FBgn0037276 CG17387 Yes Yes 8 9 +HGNC:25244 CCDC39 FB:FBgn0037276 Ccdc39 Yes Yes 8 9 HGNC:26090 CCDC40 FB:FBgn0262123 l(2)41Ab Yes Yes 8 9 HGNC:26528 CCDC42 FB:FBgn0032769 CG10750 Yes Yes 4 9 HGNC:26528 CCDC42 FB:FBgn0032768 CG17564 Yes Yes 4 9 @@ -1716,7 +1714,7 @@ HGNC:26472 CCDC43 FB:FBgn0032101 CG9586 Yes Yes 8 9 HGNC:24856 CCDC47 FB:FBgn0031544 CG17593 Yes Yes 9 9 HGNC:18111 CCDC50 FB:FBgn0032681 CG10283 Yes Yes 5 9 HGNC:18782 CCDC6 FB:FBgn0036685 CG6664 Yes Yes 8 9 -HGNC:26669 CCDC63 FB:FBgn0038452 CG14905 Yes Yes 7 9 +HGNC:26669 CCDC63 FB:FBgn0038452 Ccdc114 Yes Yes 7 9 HGNC:26669 CCDC63 FB:FBgn0039070 wam No Yes 6 9 HGNC:29937 CCDC65 FB:FBgn0050259 CG30259 Yes Yes 8 9 HGNC:27709 CCDC66 FB:FBgn0037014 CG13251 Yes Yes 2 9 @@ -1806,9 +1804,9 @@ HGNC:1712 CDA FB:FBgn0032003 CG8349 No Yes 3 9 HGNC:1712 CDA FB:FBgn0032002 CG8353 Yes Yes 7 9 HGNC:1712 CDA FB:FBgn0032001 CG8360 Yes Yes 7 9 HGNC:1713 CDAN1 FB:FBgn0024510 dlt Yes Yes 7 9 -HGNC:1718 CDC14A FB:FBgn0031952 cdc14 Yes Yes 5 9 -HGNC:1719 CDC14B FB:FBgn0031952 cdc14 Yes No 4 9 -HGNC:22427 CDC14C FB:FBgn0031952 cdc14 Yes No 4 9 +HGNC:1718 CDC14A FB:FBgn0031952 Cdc14 Yes Yes 5 9 +HGNC:1719 CDC14B FB:FBgn0031952 Cdc14 Yes No 4 9 +HGNC:22427 CDC14C FB:FBgn0031952 Cdc14 Yes No 4 9 HGNC:1720 CDC16 FB:FBgn0025781 Cdc16 Yes Yes 8 9 HGNC:1723 CDC20 FB:FBgn0001086 fzy Yes Yes 9 9 HGNC:24222 CDC20B FB:FBgn0001086 fzy Yes No 3 9 @@ -1901,7 +1899,7 @@ HGNC:1834 CEBPB FB:FBgn0005638 slbo Yes No 4 9 HGNC:1835 CEBPD FB:FBgn0005638 slbo Yes No 4 9 HGNC:1836 CEBPE FB:FBgn0005638 slbo Yes No 4 9 HGNC:1837 CEBPG FB:FBgn0036126 Irbp18 Yes Yes 4 9 -HGNC:24218 CEBPZ FB:FBgn0036124 CG7839 Yes Yes 9 9 +HGNC:24218 CEBPZ FB:FBgn0036124 Noc1 Yes Yes 9 9 HGNC:49288 CEBPZOS FB:FBgn0259717 CG42371 Yes Yes 7 9 HGNC:1840 CECR2 FB:FBgn0261934 dikar Yes Yes 3 9 HGNC:2549 CELF1 FB:FBgn0000114 bru1 Yes Yes 7 9 @@ -2651,8 +2649,8 @@ HGNC:2350 CREBL2 FB:FBgn0032202 REPTOR-BP Yes Yes 8 9 HGNC:24050 CREBRF FB:FBgn0039209 REPTOR Yes Yes 4 9 HGNC:2351 CREG1 FB:FBgn0025456 CREG Yes Yes 9 9 HGNC:14272 CREG2 FB:FBgn0025456 CREG Yes No 6 9 -HGNC:14630 CRELD1 FB:FBgn0031217 CG11377 Yes Yes 7 9 -HGNC:28150 CRELD2 FB:FBgn0031217 CG11377 Yes Yes 7 9 +HGNC:14630 CRELD1 FB:FBgn0031217 Creld Yes Yes 7 9 +HGNC:28150 CRELD2 FB:FBgn0031217 Creld Yes Yes 7 9 HGNC:2352 CREM FB:FBgn0265784 CrebB Yes Yes 6 9 HGNC:2356 CRHBP FB:FBgn0039770 CG15537 Yes Yes 9 9 HGNC:2357 CRHR1 FB:FBgn0033932 Dh44-R1 Yes Yes 9 9 @@ -2764,8 +2762,8 @@ HGNC:15879 CTNNBL1 FB:FBgn0037644 CG11964 Yes Yes 9 9 HGNC:2515 CTNND1 FB:FBgn0260799 p120ctn Yes No 4 9 HGNC:2516 CTNND2 FB:FBgn0260799 p120ctn Yes No 6 9 HGNC:2518 CTNS FB:FBgn0039045 Ctns Yes Yes 9 9 -HGNC:2519 CTPS1 FB:FBgn0266452 CTPsyn Yes Yes 9 9 -HGNC:2520 CTPS2 FB:FBgn0266452 CTPsyn Yes Yes 9 9 +HGNC:2519 CTPS1 FB:FBgn0266452 Ctps Yes Yes 9 9 +HGNC:2520 CTPS2 FB:FBgn0266452 Ctps Yes Yes 9 9 HGNC:16850 CTR9 FB:FBgn0035205 Ctr9 Yes Yes 9 9 HGNC:2523 CTRC FB:FBgn0031248 CG11912 Yes Yes 2 9 HGNC:2527 CTSB FB:FBgn0030521 CtsB Yes Yes 8 9 @@ -2781,8 +2779,8 @@ HGNC:2537 CTSL FB:FBgn0013770 Cp1 Yes Yes 7 9 HGNC:2538 CTSV FB:FBgn0013770 Cp1 Yes No 6 9 HGNC:3338 CTTN FB:FBgn0025865 Cortactin Yes Yes 8 9 HGNC:25330 CTTNBP2NL FB:FBgn0034308 Naus Yes Yes 6 9 -HGNC:29590 CTU1 FB:FBgn0033375 CG8078 Yes Yes 9 9 -HGNC:28005 CTU2 FB:FBgn0032793 CG10189 Yes Yes 7 9 +HGNC:29590 CTU1 FB:FBgn0033375 Ctu1 Yes Yes 9 9 +HGNC:28005 CTU2 FB:FBgn0032793 Ctu2 Yes Yes 7 9 HGNC:2548 CUBN FB:FBgn0052702 Cubn Yes Yes 7 9 HGNC:2548 CUBN FB:FBgn0259140 Cubn2 No Yes 4 9 HGNC:31350 CUEDC1 FB:FBgn0035283 CG12024 Yes Yes 9 9 @@ -2859,20 +2857,20 @@ HGNC:2606 CYP27B1 FB:FBgn0050489 Cyp12d1-p Yes Yes 4 9 HGNC:2606 CYP27B1 FB:FBgn0037817 Cyp12e1 No Yes 3 9 HGNC:2606 CYP27B1 FB:FBgn0033753 Cyp301a1 No Yes 3 9 HGNC:2606 CYP27B1 FB:FBgn0033524 Cyp49a1 No Yes 3 9 -HGNC:2608 CYP2A13 FB:FBgn0004959 phm Yes No 3 9 -HGNC:2610 CYP2A6 FB:FBgn0004959 phm Yes No 3 9 +HGNC:2608 CYP2A13 FB:FBgn0004959 phtm Yes No 3 9 +HGNC:2610 CYP2A6 FB:FBgn0004959 phtm Yes No 3 9 HGNC:2615 CYP2B6 FB:FBgn0001992 Cyp303a1 Yes Yes 3 9 HGNC:2615 CYP2B6 FB:FBgn0036910 Cyp305a1 Yes Yes 3 9 -HGNC:2615 CYP2B6 FB:FBgn0004959 phm Yes No 3 9 -HGNC:2621 CYP2C19 FB:FBgn0004959 phm Yes No 3 9 -HGNC:2622 CYP2C8 FB:FBgn0004959 phm Yes No 3 9 -HGNC:2623 CYP2C9 FB:FBgn0004959 phm Yes No 3 9 +HGNC:2615 CYP2B6 FB:FBgn0004959 phtm Yes No 3 9 +HGNC:2621 CYP2C19 FB:FBgn0004959 phtm Yes No 3 9 +HGNC:2622 CYP2C8 FB:FBgn0004959 phtm Yes No 3 9 +HGNC:2623 CYP2C9 FB:FBgn0004959 phtm Yes No 3 9 HGNC:2625 CYP2D6 FB:FBgn0010383 Cyp18a1 Yes No 3 9 HGNC:2634 CYP2J2 FB:FBgn0010383 Cyp18a1 Yes No 4 9 HGNC:2634 CYP2J2 FB:FBgn0001992 Cyp303a1 No Yes 3 9 HGNC:2634 CYP2J2 FB:FBgn0036910 Cyp305a1 No Yes 3 9 HGNC:20580 CYP2R1 FB:FBgn0010383 Cyp18a1 Yes No 4 9 -HGNC:20580 CYP2R1 FB:FBgn0004959 phm Yes Yes 4 9 +HGNC:20580 CYP2R1 FB:FBgn0004959 phtm Yes Yes 4 9 HGNC:20582 CYP2U1 FB:FBgn0010383 Cyp18a1 Yes Yes 5 9 HGNC:20243 CYP2W1 FB:FBgn0001992 Cyp303a1 Yes Yes 3 9 HGNC:20243 CYP2W1 FB:FBgn0036910 Cyp305a1 Yes Yes 3 9 @@ -3210,8 +3208,8 @@ HGNC:30368 DLGAP3 FB:FBgn0259978 vlc Yes Yes 4 9 HGNC:24476 DLGAP4 FB:FBgn0259978 vlc Yes Yes 4 9 HGNC:16864 DLGAP5 FB:FBgn0033845 mars Yes Yes 4 9 HGNC:2907 DLK1 FB:FBgn0261514 NimA Yes Yes 2 9 -HGNC:2908 DLL1 FB:FBgn0000463 Dl Yes No 7 9 -HGNC:2910 DLL4 FB:FBgn0000463 Dl Yes Yes 8 9 +HGNC:2908 DLL1 FB:FBgn0000463 Delta Yes No 7 9 +HGNC:2910 DLL4 FB:FBgn0000463 Delta Yes Yes 8 9 HGNC:2911 DLST FB:FBgn0037891 CG5214 Yes Yes 9 9 HGNC:2914 DLX1 FB:FBgn0000157 Dll Yes No 4 9 HGNC:2915 DLX2 FB:FBgn0000157 Dll Yes No 5 9 @@ -3235,9 +3233,8 @@ HGNC:25176 DNAAF10 FB:FBgn0036771 Wdr92 Yes Yes 9 9 HGNC:16725 DNAAF11 FB:FBgn0014395 tilB Yes Yes 9 9 HGNC:20188 DNAAF2 FB:FBgn0033224 Nop17l Yes Yes 7 9 HGNC:30492 DNAAF3 FB:FBgn0034352 Dnaaf3 Yes Yes 9 9 -HGNC:21493 DNAAF4 FB:FBgn0032345 CG14921 Yes Yes 4 9 -HGNC:26013 DNAAF5 FB:FBgn0051320 HEATR2 Yes Yes 8 9 -HGNC:28570 DNAAF6 FB:FBgn0036437 CG5048 Yes Yes 8 9 +HGNC:21493 DNAAF4 FB:FBgn0032345 Dnaaf4 Yes Yes 4 9 +HGNC:28570 DNAAF6 FB:FBgn0036437 Dnaaf6 Yes Yes 8 9 HGNC:2941 DNAH10 FB:FBgn0013813 Dhc98D Yes Yes 7 9 HGNC:2942 DNAH11 FB:FBgn0039510 CG3339 Yes No 3 9 HGNC:2943 DNAH12 FB:FBgn0013811 Dhc62B Yes Yes 3 9 @@ -3304,7 +3301,7 @@ HGNC:12392 DNAJC7 FB:FBgn0032586 Tpr2 Yes Yes 8 9 HGNC:15470 DNAJC8 FB:FBgn0039116 CG10375 Yes Yes 9 9 HGNC:19123 DNAJC9 FB:FBgn0037878 CG6693 Yes Yes 9 9 HGNC:23247 DNAL1 FB:FBgn0028858 CG10839 No Yes 7 9 -HGNC:23247 DNAL1 FB:FBgn0033408 CG8800 Yes Yes 9 9 +HGNC:23247 DNAL1 FB:FBgn0033408 ODA-Dnal1 Yes Yes 9 9 HGNC:2955 DNAL4 FB:FBgn0033687 CG8407 Yes Yes 9 9 HGNC:14353 DNALI1 FB:FBgn0037962 Dnali1 Yes Yes 9 9 HGNC:2960 DNASE2 FB:FBgn0000477 DNaseII Yes Yes 9 9 @@ -3575,6 +3572,8 @@ HGNC:3213 EEF1G FB:FBgn0029176 eEF1γ Yes Yes 9 9 HGNC:3214 EEF2 FB:FBgn0000559 eEF2 Yes Yes 9 9 HGNC:32221 EEF2KMT FB:FBgn0031003 CG7889 Yes Yes 8 9 HGNC:24614 EEFSEC FB:FBgn0034627 eEFSec Yes Yes 9 9 +HGNC:31419 EEIG1 FB:FBgn0032938 CG8671 Yes Yes 8 9 +HGNC:27637 EEIG2 FB:FBgn0032938 CG8671 Yes Yes 8 9 HGNC:28166 EFCAB2 FB:FBgn0034481 CG11041 Yes Yes 5 9 HGNC:28166 EFCAB2 FB:FBgn0034592 CG9406 Yes Yes 5 9 HGNC:26330 EFHB FB:FBgn0052086 CG32086 Yes Yes 4 9 @@ -3756,9 +3755,9 @@ HGNC:26292 ELOVL7 FB:FBgn0038986 sit No Yes 4 9 HGNC:5959 ELP1 FB:FBgn0037926 Elp1 Yes Yes 9 9 HGNC:18248 ELP2 FB:FBgn0033540 Elp2 Yes Yes 9 9 HGNC:20696 ELP3 FB:FBgn0031604 Elp3 Yes Yes 9 9 -HGNC:1171 ELP4 FB:FBgn0031711 CG6907 Yes Yes 8 9 -HGNC:30617 ELP5 FB:FBgn0015359 CG2034 Yes Yes 2 9 -HGNC:25976 ELP6 FB:FBgn0086371 poly Yes Yes 4 9 +HGNC:1171 ELP4 FB:FBgn0031711 Elp4 Yes Yes 8 9 +HGNC:30617 ELP5 FB:FBgn0015359 Elp5 Yes Yes 2 9 +HGNC:25976 ELP6 FB:FBgn0086371 Elp6 Yes Yes 4 9 HGNC:28957 EMC1 FB:FBgn0037530 EMC1 Yes Yes 8 9 HGNC:27609 EMC10 FB:FBgn0052441 EMC10 Yes Yes 7 9 HGNC:28963 EMC2 FB:FBgn0038462 EMC2A Yes Yes 9 9 @@ -3919,7 +3918,7 @@ HGNC:3477 ETF1 FB:FBgn0036974 eRF1 Yes Yes 9 9 HGNC:3481 ETFA FB:FBgn0010516 wal Yes Yes 8 9 HGNC:3482 ETFB FB:FBgn0039697 Etfb Yes Yes 9 9 HGNC:3483 ETFDH FB:FBgn0286783 Etf-QO Yes Yes 9 9 -HGNC:27052 ETFRF1 FB:FBgn0040985 CG6115 Yes Yes 8 9 +HGNC:27052 ETFRF1 FB:FBgn0040985 osi Yes Yes 8 9 HGNC:23287 ETHE1 FB:FBgn0050022 CG30022 Yes Yes 8 9 HGNC:24649 ETNK1 FB:FBgn0000536 eas Yes Yes 9 9 HGNC:25575 ETNK2 FB:FBgn0000536 eas Yes No 8 9 @@ -3983,10 +3982,10 @@ HGNC:3526 EZH1 FB:FBgn0000629 E(z) Yes Yes 9 9 HGNC:3527 EZH2 FB:FBgn0000629 E(z) Yes Yes 9 9 HGNC:12691 EZR FB:FBgn0011661 Moe Yes Yes 7 9 HGNC:3531 F13A1 FB:FBgn0031975 Tg Yes No 5 9 -HGNC:3547 F8A1 FB:FBgn0030671 CG8134 Yes Yes 3 9 -HGNC:31849 F8A2 FB:FBgn0030671 CG8134 Yes Yes 3 9 -HGNC:31850 F8A3 FB:FBgn0030671 CG8134 Yes Yes 3 9 -HGNC:21197 FA2H FB:FBgn0050502 fa2h Yes Yes 9 9 +HGNC:3547 F8A1 FB:FBgn0030671 Hap40 Yes Yes 3 9 +HGNC:31849 F8A2 FB:FBgn0030671 Hap40 Yes Yes 3 9 +HGNC:31850 F8A3 FB:FBgn0030671 Hap40 Yes Yes 3 9 +HGNC:21197 FA2H FB:FBgn0050502 Fa2h Yes Yes 9 9 HGNC:26440 FAAH2 FB:FBgn0033717 CG8839 Yes Yes 8 9 HGNC:34524 FABP12 FB:FBgn0037913 fabp Yes No 8 9 HGNC:3557 FABP3 FB:FBgn0037913 fabp Yes No 8 9 @@ -4005,8 +4004,6 @@ HGNC:24252 FAHD2A FB:FBgn0038924 CG6028 Yes Yes 9 9 HGNC:25318 FAHD2B FB:FBgn0036346 CG11251 No Yes 5 9 HGNC:25318 FAHD2B FB:FBgn0038924 CG6028 Yes Yes 9 9 HGNC:18703 FAIM FB:FBgn0033985 CG10257 Yes Yes 9 9 -HGNC:31419 FAM102A FB:FBgn0032938 CG8671 Yes Yes 8 9 -HGNC:27637 FAM102B FB:FBgn0032938 CG8671 Yes Yes 8 9 HGNC:30827 FAM107A FB:FBgn0032886 CG9328 Yes No 5 9 HGNC:23726 FAM107B FB:FBgn0032886 CG9328 Yes Yes 7 9 HGNC:16188 FAM110A FB:FBgn0035477 CG14982 Yes Yes 2 9 @@ -4254,8 +4251,8 @@ HGNC:3758 FLOT2 FB:FBgn0264078 Flo2 Yes Yes 8 9 HGNC:3763 FLT1 FB:FBgn0032006 Pvr Yes Yes 5 9 HGNC:3765 FLT3 FB:FBgn0032006 Pvr Yes No 3 9 HGNC:3767 FLT4 FB:FBgn0032006 Pvr Yes No 4 9 -HGNC:24682 FLVCR1 FB:FBgn0033196 CG1358 Yes Yes 9 9 -HGNC:20105 FLVCR2 FB:FBgn0033196 CG1358 Yes No 8 9 +HGNC:24682 FLVCR1 FB:FBgn0033196 HisT Yes Yes 9 9 +HGNC:20105 FLVCR2 FB:FBgn0033196 HisT Yes No 8 9 HGNC:26946 FMC1 FB:FBgn0083953 CG34117 Yes Yes 9 9 HGNC:44671 FMC1-LUC7L2 FB:FBgn0083953 CG34117 Yes Yes 9 9 HGNC:3768 FMN1 FB:FBgn0000256 capu Yes No 4 9 @@ -4333,14 +4330,14 @@ HGNC:20842 FOXP4 FB:FBgn0262477 FoxP Yes Yes 5 9 HGNC:26927 FOXRED1 FB:FBgn0033093 CG3270 Yes Yes 8 9 HGNC:26927 FOXRED1 FB:FBgn0002021 l(2)37Bb No Yes 5 9 HGNC:3735 FOXS1 FB:FBgn0031086 fd19B Yes Yes 2 9 -HGNC:3824 FPGS FB:FBgn0051773 CG31773 No Yes 4 9 -HGNC:3824 FPGS FB:FBgn0030407 Fpgs Yes Yes 9 9 +HGNC:3824 FPGS FB:FBgn0030407 Fpgs1 Yes Yes 9 9 +HGNC:3824 FPGS FB:FBgn0051773 Fpgs2 No Yes 4 9 HGNC:1162 FRA10AC1 FB:FBgn0028932 CG16890 Yes Yes 9 9 HGNC:3954 FRG1 FB:FBgn0036964 FRG1 Yes Yes 9 9 HGNC:3955 FRK FB:FBgn0264959 Src42A Yes Yes 9 9 HGNC:21240 FRMD1 FB:FBgn0004583 ex Yes Yes 6 9 -HGNC:24125 FRMD3 FB:FBgn0032225 CG5022 Yes No 8 9 -HGNC:28214 FRMD5 FB:FBgn0032225 CG5022 Yes Yes 9 9 +HGNC:24125 FRMD3 FB:FBgn0032225 Frmd5 Yes No 8 9 +HGNC:28214 FRMD5 FB:FBgn0032225 Frmd5 Yes Yes 9 9 HGNC:19839 FRMD6 FB:FBgn0004583 ex Yes No 3 9 HGNC:8079 FRMD7 FB:FBgn0265082 Cdep Yes Yes 3 9 HGNC:25462 FRMD8 FB:FBgn0039282 Bili Yes Yes 7 9 @@ -4620,9 +4617,9 @@ HGNC:4289 GK FB:FBgn0035266 Gk2 No Yes 5 9 HGNC:4291 GK2 FB:FBgn0033673 CG8298 No Yes 4 9 HGNC:4291 GK2 FB:FBgn0025592 Gk1 Yes Yes 9 9 HGNC:4291 GK2 FB:FBgn0035266 Gk2 No Yes 5 9 -HGNC:4292 GK3P FB:FBgn0033673 CG8298 No Yes 4 9 -HGNC:4292 GK3P FB:FBgn0025592 Gk1 Yes Yes 9 9 -HGNC:4292 GK3P FB:FBgn0035266 Gk2 No Yes 5 9 +HGNC:4292 GK3 FB:FBgn0033673 CG8298 No Yes 4 9 +HGNC:4292 GK3 FB:FBgn0025592 Gk1 Yes Yes 9 9 +HGNC:4292 GK3 FB:FBgn0035266 Gk2 No Yes 5 9 HGNC:28635 GK5 FB:FBgn0035392 CG1271 Yes Yes 9 9 HGNC:4296 GLA FB:FBgn0034117 CG7997 Yes No 5 9 HGNC:4298 GLB1 FB:FBgn0260746 Ect3 Yes No 8 9 @@ -4744,7 +4741,7 @@ HGNC:29670 GNPTAB FB:FBgn0033392 Gnptab Yes Yes 8 9 HGNC:4421 GNRHR FB:FBgn0025595 AkhR Yes Yes 9 9 HGNC:16341 GNRHR2 FB:FBgn0025595 AkhR Yes No 8 9 HGNC:4422 GNS FB:FBgn0033836 CG18278 Yes Yes 7 9 -HGNC:4424 GOLGA1 FB:FBgn0086757 cbs Yes Yes 9 9 +HGNC:4424 GOLGA1 FB:FBgn0086757 Golgin97 Yes Yes 9 9 HGNC:4425 GOLGA2 FB:FBgn0034697 GM130 Yes Yes 8 9 HGNC:4427 GOLGA4 FB:FBgn0034854 Golgin245 Yes Yes 8 9 HGNC:4428 GOLGA5 FB:FBgn0039188 Golgin84 Yes Yes 7 9 @@ -6456,7 +6453,7 @@ HGNC:26087 HEATR3 FB:FBgn0037439 CG10286 Yes Yes 8 9 HGNC:20276 HEATR5A FB:FBgn0037541 CG2747 Yes Yes 9 9 HGNC:29273 HEATR5B FB:FBgn0037541 CG2747 Yes Yes 9 9 HGNC:24076 HEATR6 FB:FBgn0025621 CG16989 Yes Yes 8 9 -HGNC:21041 HECA FB:FBgn0010113 hdc Yes Yes 8 9 +HGNC:21041 HECA FB:FBgn0010113 heca Yes Yes 8 9 HGNC:20157 HECTD1 FB:FBgn0032208 Ufd4 Yes Yes 9 9 HGNC:22195 HECW1 FB:FBgn0261931 Hecw Yes No 7 9 HGNC:29853 HECW2 FB:FBgn0261931 Hecw Yes Yes 8 9 @@ -6473,7 +6470,7 @@ HGNC:26072 HERC6 FB:FBgn0035207 Herc4 Yes No 3 9 HGNC:13744 HERPUD1 FB:FBgn0031950 Herp Yes Yes 8 9 HGNC:21915 HERPUD2 FB:FBgn0031950 Herp Yes Yes 8 9 HGNC:5192 HES1 FB:FBgn0010109 dpn Yes Yes 6 9 -HGNC:5192 HES1 FB:FBgn0001168 h No Yes 5 9 +HGNC:5192 HES1 FB:FBgn0001168 hry No Yes 5 9 HGNC:16005 HES2 FB:FBgn0002609 E(spl)m3-HLH No Yes 3 9 HGNC:16005 HES2 FB:FBgn0002631 E(spl)m5-HLH Yes Yes 4 9 HGNC:16005 HES2 FB:FBgn0002633 E(spl)m7-HLH No Yes 3 9 @@ -6546,7 +6543,7 @@ HGNC:4976 HLCS FB:FBgn0037332 Hcs Yes Yes 8 9 HGNC:4977 HLF FB:FBgn0016694 Pdp1 Yes Yes 6 9 HGNC:4978 HLX FB:FBgn0001170 H2.0 Yes Yes 6 9 HGNC:16435 HM13 FB:FBgn0031260 Spp Yes Yes 9 9 -HGNC:4982 HMBS FB:FBgn0010786 Pbgd Yes Yes 6 9 +HGNC:4982 HMBS FB:FBgn0010786 Hmbs Yes Yes 6 9 HGNC:24446 HMCES FB:FBgn0037656 CG11986 Yes Yes 9 9 HGNC:21293 HMCN2 FB:FBgn0039431 plum Yes Yes 2 9 HGNC:5001 HMG20A FB:FBgn0026582 Hmg-2 Yes Yes 7 9 @@ -6797,7 +6794,7 @@ HGNC:17367 IFT57 FB:FBgn0031550 IFT57 Yes Yes 9 9 HGNC:29262 IFT80 FB:FBgn0032891 Oseg5 Yes Yes 9 9 HGNC:20606 IFT88 FB:FBgn0016919 nompB Yes Yes 9 9 HGNC:5461 IGBP1 FB:FBgn0051852 Tap42 Yes Yes 9 9 -HGNC:43611 IGBP1P2 FB:FBgn0051852 Tap42 Yes Yes 9 9 +HGNC:43611 IGBP1C FB:FBgn0051852 Tap42 Yes Yes 9 9 HGNC:5465 IGF1R FB:FBgn0283499 InR Yes Yes 8 9 HGNC:28866 IGF2BP1 FB:FBgn0285926 Imp Yes Yes 9 9 HGNC:28867 IGF2BP2 FB:FBgn0285926 Imp Yes Yes 9 9 @@ -6854,7 +6851,6 @@ HGNC:6067 INHBB FB:FBgn0024913 Actβ Yes Yes 7 9 HGNC:6068 INHBC FB:FBgn0024913 Actβ Yes Yes 7 9 HGNC:24029 INHBE FB:FBgn0024913 Actβ Yes No 3 9 HGNC:24994 INIP FB:FBgn0259720 CG42374 Yes Yes 6 9 -HGNC:26956 INO80 FB:FBgn0086613 Ino80 Yes Yes 9 9 HGNC:13324 INO80B FB:FBgn0033019 CG10395 Yes Yes 6 9 HGNC:26994 INO80C FB:FBgn0040929 CG12659 Yes Yes 7 9 HGNC:25997 INO80D FB:FBgn0086686 l(3)L1231 Yes Yes 4 9 @@ -7019,8 +7015,8 @@ HGNC:12313 JMJD1C FB:FBgn0037703 Kdm3 Yes No 5 9 HGNC:25724 JMJD4 FB:FBgn0032671 JMJD4 Yes Yes 8 9 HGNC:19355 JMJD6 FB:FBgn0038948 JMJD6 Yes Yes 9 9 HGNC:34397 JMJD7 FB:FBgn0036366 JMJD7 Yes Yes 9 9 -HGNC:28953 JOSD1 FB:FBgn0029853 CG3781 Yes Yes 9 9 -HGNC:28853 JOSD2 FB:FBgn0029853 CG3781 Yes No 7 9 +HGNC:28953 JOSD1 FB:FBgn0029853 Josd Yes Yes 9 9 +HGNC:28853 JOSD2 FB:FBgn0029853 Josd Yes No 7 9 HGNC:14201 JPH1 FB:FBgn0032129 jp Yes No 7 9 HGNC:14202 JPH2 FB:FBgn0032129 jp Yes No 7 9 HGNC:14203 JPH3 FB:FBgn0032129 jp Yes Yes 8 9 @@ -7054,7 +7050,6 @@ HGNC:17933 KAT8 FB:FBgn0014340 mof Yes Yes 8 9 HGNC:6216 KATNA1 FB:FBgn0040208 Kat60 Yes No 8 9 HGNC:28361 KATNAL1 FB:FBgn0037375 kat-60L1 No Yes 5 9 HGNC:28361 KATNAL1 FB:FBgn0040208 Kat60 Yes Yes 9 9 -HGNC:25387 KATNAL2 FB:FBgn0029656 CG10793 Yes Yes 6 9 HGNC:6217 KATNB1 FB:FBgn0040207 kat80 Yes Yes 9 9 HGNC:29173 KAZN FB:FBgn0034720 Liprin-γ Yes Yes 7 9 HGNC:20589 KCMF1 FB:FBgn0037655 Kcmf1 Yes Yes 8 9 @@ -7188,7 +7183,7 @@ HGNC:12637 KDM6A FB:FBgn0260749 Utx Yes Yes 7 9 HGNC:29012 KDM6B FB:FBgn0260749 Utx Yes No 4 9 HGNC:25840 KDM8 FB:FBgn0035166 JMJD5 Yes Yes 8 9 HGNC:6307 KDR FB:FBgn0032006 Pvr Yes Yes 5 9 -HGNC:4021 KDSR FB:FBgn0039304 CG10425 Yes Yes 9 9 +HGNC:4021 KDSR FB:FBgn0039304 Kdsr Yes Yes 9 9 HGNC:23177 KEAP1 FB:FBgn0038475 Keap1 Yes Yes 9 9 HGNC:6308 KEL FB:FBgn0032442 Nepl7 Yes Yes 3 9 HGNC:18116 KHDRBS1 FB:FBgn0034659 CG4021 Yes No 5 9 @@ -7725,8 +7720,8 @@ HGNC:23452 LIPN FB:FBgn0024740 Lip2 No Yes 4 9 HGNC:23452 LIPN FB:FBgn0023495 Lip3 Yes Yes 9 9 HGNC:23452 LIPN FB:FBgn0032264 Lip4 Yes Yes 9 9 HGNC:23452 LIPN FB:FBgn0036996 mag No Yes 6 9 -HGNC:29569 LIPT1 FB:FBgn0265178 CG44243 Yes Yes 9 9 -HGNC:37216 LIPT2 FB:FBgn0037251 CG9804 Yes Yes 9 9 +HGNC:29569 LIPT1 FB:FBgn0265178 Lipt1 Yes Yes 9 9 +HGNC:37216 LIPT2 FB:FBgn0037251 Lipt2 Yes Yes 9 9 HGNC:16841 LITAF FB:FBgn0034758 CG13510 Yes Yes 3 9 HGNC:16841 LITAF FB:FBgn0052280 CG32280 Yes No 3 9 HGNC:53927 LITAFD FB:FBgn0034870 CG13559 Yes Yes 2 9 @@ -8444,7 +8439,7 @@ HGNC:15988 MPPE1 FB:FBgn0031997 PGAP5 Yes Yes 9 9 HGNC:1306 MPPED1 FB:FBgn0036028 CG16717 Yes Yes 9 9 HGNC:1180 MPPED2 FB:FBgn0036028 CG16717 Yes Yes 9 9 HGNC:30321 MPRIP FB:FBgn0003016 osp Yes Yes 7 9 -HGNC:7224 MPV17 FB:FBgn0039930 CG11077 Yes Yes 9 9 +HGNC:7224 MPV17 FB:FBgn0039930 Mpv17 Yes Yes 9 9 HGNC:26827 MPV17L FB:FBgn0040805 CG12355 Yes Yes 9 9 HGNC:26827 MPV17L FB:FBgn0026872 CG14777 No Yes 3 9 HGNC:28177 MPV17L2 FB:FBgn0030481 CG1662 No Yes 5 9 @@ -8622,7 +8617,7 @@ HGNC:7463 MTNR1A FB:FBgn0046687 Tre1 Yes Yes 4 9 HGNC:7464 MTNR1B FB:FBgn0025631 moody Yes No 3 9 HGNC:7464 MTNR1B FB:FBgn0046687 Tre1 Yes No 3 9 HGNC:19261 MTO1 FB:FBgn0034735 CG4610 Yes Yes 9 9 -HGNC:3942 MTOR FB:FBgn0021796 Tor Yes Yes 9 9 +HGNC:3942 MTOR FB:FBgn0021796 mTor Yes Yes 9 9 HGNC:25532 MTPAP FB:FBgn0024360 MTPAP Yes Yes 8 9 HGNC:15667 MTPN FB:FBgn0051715 CG31715 Yes Yes 8 9 HGNC:15667 MTPN FB:FBgn0030982 CG7423 No Yes 6 9 @@ -8756,14 +8751,14 @@ HGNC:25126 NAF1 FB:FBgn0032701 CG10341 Yes Yes 8 9 HGNC:7631 NAGA FB:FBgn0032192 CG5731 Yes Yes 8 9 HGNC:7631 NAGA FB:FBgn0034117 CG7997 No Yes 6 9 HGNC:17174 NAGK FB:FBgn0038321 Nagk Yes Yes 9 9 -HGNC:7632 NAGLU FB:FBgn0014417 CG13397 Yes Yes 9 9 +HGNC:7632 NAGLU FB:FBgn0014417 Naglu Yes Yes 9 9 HGNC:25446 NAIF1 FB:FBgn0033971 CG10209 Yes Yes 2 9 HGNC:19082 NALCN FB:FBgn0002917 na Yes Yes 9 9 HGNC:33877 NALF1 FB:FBgn0053988 Mid1 Yes Yes 3 9 HGNC:30701 NALF2 FB:FBgn0053988 Mid1 Yes Yes 3 9 -HGNC:23044 NANOS1 FB:FBgn0002962 nos Yes Yes 4 9 -HGNC:23292 NANOS2 FB:FBgn0002962 nos Yes Yes 4 9 -HGNC:22048 NANOS3 FB:FBgn0002962 nos Yes Yes 4 9 +HGNC:23044 NANOS1 FB:FBgn0002962 nanos Yes Yes 4 9 +HGNC:23292 NANOS2 FB:FBgn0002962 nanos Yes Yes 4 9 +HGNC:22048 NANOS3 FB:FBgn0002962 nanos Yes Yes 4 9 HGNC:16140 NANP FB:FBgn0029801 CG15771 Yes Yes 8 9 HGNC:19237 NANS FB:FBgn0038045 NANS Yes Yes 9 9 HGNC:7637 NAP1L1 FB:FBgn0015268 Nap1 Yes Yes 7 9 @@ -8966,6 +8961,8 @@ HGNC:20271 NGDN FB:FBgn0031736 CG11030 Yes Yes 9 9 HGNC:7807 NGEF FB:FBgn0261547 Exn Yes No 4 9 HGNC:17646 NGLY1 FB:FBgn0033050 Pngl Yes Yes 9 9 HGNC:18077 NGRN FB:FBgn0039336 CG4553 Yes Yes 4 9 +HGNC:11075 NHERF1 FB:FBgn0010620 CG10939 Yes Yes 3 9 +HGNC:11076 NHERF2 FB:FBgn0010620 CG10939 Yes Yes 3 9 HGNC:7817 NHLH1 FB:FBgn0011277 HLH4C Yes Yes 5 9 HGNC:24731 NHLRC2 FB:FBgn0250830 CG12547 Yes Yes 9 9 HGNC:14377 NHP2 FB:FBgn0029148 NHP2 Yes Yes 9 9 @@ -9070,8 +9067,8 @@ HGNC:16454 NMUR2 FB:FBgn0038140 PK2-R1 No Yes 4 9 HGNC:16454 NMUR2 FB:FBgn0038139 PK2-R2 No Yes 4 9 HGNC:28473 NOA1 FB:FBgn0034307 CG10914 Yes Yes 9 9 HGNC:29540 NOB1 FB:FBgn0030177 CG2972 Yes Yes 9 9 -HGNC:24517 NOC2L FB:FBgn0032925 CG9246 Yes Yes 9 9 -HGNC:24034 NOC3L FB:FBgn0037489 CG1234 Yes Yes 9 9 +HGNC:24517 NOC2L FB:FBgn0032925 Noc2 Yes Yes 9 9 +HGNC:24034 NOC3L FB:FBgn0037489 Noc3 Yes Yes 9 9 HGNC:28461 NOC4L FB:FBgn0029672 CG2875 Yes Yes 8 9 HGNC:14254 NOCT FB:FBgn0261808 cu Yes Yes 7 9 HGNC:25862 NOL10 FB:FBgn0261535 l(2)34Fd Yes Yes 9 9 @@ -9335,7 +9332,7 @@ HGNC:8101 OCA2 FB:FBgn0031649 hoe2 Yes Yes 8 9 HGNC:16074 OCIAD1 FB:FBgn0034793 asrij Yes Yes 9 9 HGNC:28685 OCIAD2 FB:FBgn0034793 asrij Yes No 4 9 HGNC:8108 OCRL FB:FBgn0023508 Ocrl Yes No 8 9 -HGNC:26560 ODAD1 FB:FBgn0038452 CG14905 Yes No 4 9 +HGNC:26560 ODAD1 FB:FBgn0038452 Ccdc114 Yes No 4 9 HGNC:25583 ODAD2 FB:FBgn0031905 gudu Yes Yes 7 9 HGNC:28303 ODAD3 FB:FBgn0036219 CCDC151 Yes Yes 7 9 HGNC:25280 ODAD4 FB:FBgn0034692 CG13502 Yes Yes 4 9 @@ -9684,7 +9681,7 @@ HGNC:30259 PDXP FB:FBgn0036760 CG5567 Yes Yes 9 9 HGNC:30259 PDXP FB:FBgn0036759 CG5577 No Yes 5 9 HGNC:18486 PDZD2 FB:FBgn0087007 bbg Yes Yes 2 9 HGNC:21167 PDZD4 FB:FBgn0024728 Slip1 Yes No 6 9 -HGNC:26974 PDZD8 FB:FBgn0030358 CG10362 Yes Yes 9 9 +HGNC:26974 PDZD8 FB:FBgn0030358 Pdzd8 Yes Yes 9 9 HGNC:17704 PDZRN3 FB:FBgn0024728 Slip1 Yes No 6 9 HGNC:30552 PDZRN4 FB:FBgn0024728 Slip1 Yes Yes 8 9 HGNC:33631 PEAR1 FB:FBgn0027594 drpr Yes No 4 9 @@ -11063,7 +11060,7 @@ HGNC:9971 RFC3 FB:FBgn0028700 RfC38 Yes Yes 9 9 HGNC:9972 RFC4 FB:FBgn0030871 CG8142 Yes Yes 9 9 HGNC:9973 RFC5 FB:FBgn0032244 RfC3 Yes Yes 9 9 HGNC:24821 RFFL FB:FBgn0033783 CG17019 Yes Yes 8 9 -HGNC:30324 RFK FB:FBgn0014930 CG2846 Yes Yes 9 9 +HGNC:30324 RFK FB:FBgn0014930 Rfk Yes Yes 9 9 HGNC:9974 RFNG FB:FBgn0011591 fng Yes No 8 9 HGNC:30220 RFT1 FB:FBgn0027564 CG3149 Yes Yes 9 9 HGNC:9982 RFX1 FB:FBgn0020379 Rfx Yes No 7 9 @@ -11288,8 +11285,8 @@ HGNC:10345 RPL35A FB:FBgn0037328 RpL35A Yes Yes 9 9 HGNC:13631 RPL36 FB:FBgn0002579 RpL36 Yes Yes 9 9 HGNC:10359 RPL36A FB:FBgn0031980 RpL36A Yes Yes 8 9 HGNC:10346 RPL36AL FB:FBgn0031980 RpL36A Yes Yes 8 9 -HGNC:10347 RPL37 FB:FBgn0030616 RpL37a Yes Yes 8 9 -HGNC:10347 RPL37 FB:FBgn0034822 RpL37b No Yes 4 9 +HGNC:10347 RPL37 FB:FBgn0030616 RpL37-1 Yes Yes 8 9 +HGNC:10347 RPL37 FB:FBgn0034822 RpL37-2 No Yes 4 9 HGNC:10348 RPL37A FB:FBgn0261608 RpL37A Yes Yes 8 9 HGNC:35645 RPL37AP8 FB:FBgn0261608 RpL37A Yes No 5 9 HGNC:10349 RPL38 FB:FBgn0040007 RpL38 Yes Yes 9 9 @@ -11475,11 +11472,11 @@ HGNC:10526 SALL2 FB:FBgn0000287 salr Yes No 3 9 HGNC:10527 SALL3 FB:FBgn0261648 salm Yes Yes 6 9 HGNC:15924 SALL4 FB:FBgn0261648 salm Yes No 4 9 HGNC:15924 SALL4 FB:FBgn0000287 salr Yes No 4 9 -HGNC:17958 SAMD1 FB:FBgn0024993 CG2662 Yes Yes 2 9 +HGNC:17958 SAMD1 FB:FBgn0024993 Lint-O Yes Yes 2 9 HGNC:16129 SAMD10 FB:FBgn0050476 ave Yes Yes 5 9 HGNC:28706 SAMD11 FB:FBgn0032330 Samuel Yes Yes 3 9 HGNC:31750 SAMD12 FB:FBgn0050476 ave Yes Yes 5 9 -HGNC:24582 SAMD13 FB:FBgn0024993 CG2662 Yes Yes 2 9 +HGNC:24582 SAMD13 FB:FBgn0024993 Lint-O Yes Yes 2 9 HGNC:18631 SAMD15 FB:FBgn0031763 CG13996 Yes Yes 2 9 HGNC:18631 SAMD15 FB:FBgn0031644 CG15625 Yes Yes 2 9 HGNC:23023 SAMD4A FB:FBgn0016070 smg Yes Yes 7 9 @@ -11530,9 +11527,9 @@ HGNC:22973 SBNO1 FB:FBgn0028887 CG3491 No Yes 4 9 HGNC:22973 SBNO1 FB:FBgn0265630 sno Yes Yes 9 9 HGNC:29158 SBNO2 FB:FBgn0028887 CG3491 Yes No 3 9 HGNC:29158 SBNO2 FB:FBgn0265630 sno Yes No 3 9 -HGNC:30362 SBSPON FB:FBgn0259241 CG42339 Yes Yes 5 9 -HGNC:19304 SCAF4 FB:FBgn0034598 CG4266 Yes Yes 6 9 -HGNC:20959 SCAF8 FB:FBgn0034598 CG4266 Yes Yes 6 9 +HGNC:30362 SBSPON FB:FBgn0259241 vex Yes Yes 5 9 +HGNC:19304 SCAF4 FB:FBgn0034598 Isha Yes Yes 6 9 +HGNC:20959 SCAF8 FB:FBgn0034598 Isha Yes Yes 6 9 HGNC:26709 SCAI FB:FBgn0035677 CG13293 Yes Yes 9 9 HGNC:10563 SCAMP1 FB:FBgn0040285 Scamp Yes Yes 9 9 HGNC:10564 SCAMP2 FB:FBgn0040285 Scamp Yes No 8 9 @@ -12728,8 +12725,6 @@ HGNC:26175 SLC8B1 FB:FBgn0034156 CG5348 No Yes 8 9 HGNC:11071 SLC9A1 FB:FBgn0040297 Nhe2 Yes No 3 9 HGNC:11072 SLC9A2 FB:FBgn0040297 Nhe2 Yes No 3 9 HGNC:11073 SLC9A3 FB:FBgn0040297 Nhe2 Yes Yes 7 9 -HGNC:11075 SLC9A3R1 FB:FBgn0010620 CG10939 Yes Yes 3 9 -HGNC:11076 SLC9A3R2 FB:FBgn0010620 CG10939 Yes Yes 3 9 HGNC:11077 SLC9A4 FB:FBgn0040297 Nhe2 Yes No 3 9 HGNC:11078 SLC9A5 FB:FBgn0040297 Nhe2 Yes Yes 7 9 HGNC:11079 SLC9A6 FB:FBgn0028703 Nhe3 Yes No 8 9 @@ -12780,7 +12775,6 @@ HGNC:15811 SLX9 FB:FBgn0035393 CG16753 Yes Yes 4 9 HGNC:6767 SMAD1 FB:FBgn0011648 Mad Yes Yes 7 9 HGNC:6768 SMAD2 FB:FBgn0025800 Smox Yes Yes 5 9 HGNC:6769 SMAD3 FB:FBgn0025800 Smox Yes Yes 5 9 -HGNC:6770 SMAD4 FB:FBgn0011655 Med Yes Yes 7 9 HGNC:6771 SMAD5 FB:FBgn0011648 Mad Yes Yes 7 9 HGNC:6772 SMAD6 FB:FBgn0020493 Dad Yes Yes 5 9 HGNC:6773 SMAD7 FB:FBgn0020493 Dad Yes Yes 5 9 @@ -12806,7 +12800,7 @@ HGNC:14011 SMC2 FB:FBgn0027783 SMC2 Yes Yes 9 9 HGNC:2468 SMC3 FB:FBgn0015615 SMC3 Yes Yes 9 9 HGNC:14013 SMC4 FB:FBgn0015391 glu Yes Yes 9 9 HGNC:20465 SMC5 FB:FBgn0052438 SMC5 Yes Yes 9 9 -HGNC:20466 SMC6 FB:FBgn0266282 jnj Yes Yes 9 9 +HGNC:20466 SMC6 FB:FBgn0266282 SMC6 Yes Yes 9 9 HGNC:24810 SMCO4 FB:FBgn0053169 CG33169 Yes Yes 5 9 HGNC:25055 SMDT1 FB:FBgn0062440 EMRE Yes Yes 8 9 HGNC:30045 SMG1 FB:FBgn0263968 nonC Yes Yes 8 9 @@ -12818,7 +12812,6 @@ HGNC:25154 SMIM12 FB:FBgn0085257 CG34228 Yes Yes 8 9 HGNC:27356 SMIM13 FB:FBgn0259932 CG42455 Yes Yes 6 9 HGNC:27321 SMIM14 FB:FBgn0035020 CG13585 Yes Yes 9 9 HGNC:37260 SMIM20 FB:FBgn0085271 CG34242 Yes Yes 3 9 -HGNC:37257 SMIM4 FB:FBgn0052736 CG32736 Yes Yes 9 9 HGNC:21401 SMIM8 FB:FBgn0052448 CG32448 Yes Yes 8 9 HGNC:43561 SMKR1 FB:FBgn0266615 CG45122 Yes Yes 7 9 HGNC:11117 SMN1 FB:FBgn0036641 Smn Yes Yes 9 9 @@ -12922,7 +12915,7 @@ HGNC:29846 SOCS7 FB:FBgn0030869 Socs16D Yes Yes 5 9 HGNC:11179 SOD1 FB:FBgn0003462 Sod1 Yes Yes 8 9 HGNC:11179 SOD1 FB:FBgn0033631 Sod3 No Yes 3 9 HGNC:11180 SOD2 FB:FBgn0010213 Sod2 Yes Yes 9 9 -HGNC:11181 SOD3 FB:FBgn0039386 CG5948 Yes Yes 3 9 +HGNC:11181 SOD3 FB:FBgn0039386 Sodq Yes Yes 3 9 HGNC:16111 SOGA1 FB:FBgn0031869 CG18304 Yes Yes 2 9 HGNC:21494 SOGA3 FB:FBgn0031869 CG18304 Yes Yes 2 9 HGNC:11183 SON FB:FBgn0037716 Son Yes Yes 4 9 @@ -13141,12 +13134,12 @@ HGNC:18441 ST7L FB:FBgn0037026 CG3634 Yes No 7 9 HGNC:11353 STAC FB:FBgn0263980 Stacl Yes Yes 2 9 HGNC:23990 STAC2 FB:FBgn0263980 Stacl Yes Yes 2 9 HGNC:28423 STAC3 FB:FBgn0263980 Stacl Yes Yes 2 9 -HGNC:11354 STAG1 FB:FBgn0020616 SA Yes Yes 9 9 -HGNC:11354 STAG1 FB:FBgn0043865 SA-2 No Yes 3 9 -HGNC:11355 STAG2 FB:FBgn0020616 SA Yes Yes 9 9 -HGNC:11355 STAG2 FB:FBgn0043865 SA-2 No Yes 3 9 -HGNC:11356 STAG3 FB:FBgn0020616 SA Yes No 8 9 -HGNC:11356 STAG3 FB:FBgn0043865 SA-2 No Yes 3 9 +HGNC:11354 STAG1 FB:FBgn0020616 SA1 Yes Yes 9 9 +HGNC:11354 STAG1 FB:FBgn0043865 SA2 No Yes 3 9 +HGNC:11355 STAG2 FB:FBgn0020616 SA1 Yes Yes 9 9 +HGNC:11355 STAG2 FB:FBgn0043865 SA2 No Yes 3 9 +HGNC:11356 STAG3 FB:FBgn0020616 SA1 Yes No 8 9 +HGNC:11356 STAG3 FB:FBgn0043865 SA2 No Yes 3 9 HGNC:11357 STAM FB:FBgn0027363 Stam Yes Yes 9 9 HGNC:11358 STAM2 FB:FBgn0027363 Stam Yes No 8 9 HGNC:16950 STAMBP FB:FBgn0039773 CG2224 Yes Yes 9 9 @@ -13475,11 +13468,11 @@ HGNC:17791 TBC1D8 FB:FBgn0037074 Tbc1d8-9 Yes Yes 9 9 HGNC:24715 TBC1D8B FB:FBgn0037074 Tbc1d8-9 Yes Yes 9 9 HGNC:21710 TBC1D9 FB:FBgn0037074 Tbc1d8-9 Yes Yes 9 9 HGNC:29097 TBC1D9B FB:FBgn0037074 Tbc1d8-9 Yes Yes 9 9 -HGNC:11579 TBCA FB:FBgn0039869 CG1890 Yes Yes 8 9 HGNC:11579 TBCA FB:FBgn0030614 CG9072 No Yes 3 9 -HGNC:1989 TBCB FB:FBgn0034451 TBCB Yes Yes 8 9 -HGNC:11580 TBCC FB:FBgn0051961 TBCC Yes Yes 9 9 -HGNC:11581 TBCD FB:FBgn0027509 TBCD Yes Yes 9 9 +HGNC:11579 TBCA FB:FBgn0039869 Tbca Yes Yes 8 9 +HGNC:1989 TBCB FB:FBgn0034451 Tbcb Yes Yes 8 9 +HGNC:11580 TBCC FB:FBgn0051961 Tbcc Yes Yes 9 9 +HGNC:11581 TBCD FB:FBgn0027509 Tbcd Yes Yes 9 9 HGNC:11582 TBCE FB:FBgn0033055 Tbce Yes Yes 9 9 HGNC:28115 TBCEL FB:FBgn0265512 mlt Yes Yes 9 9 HGNC:28261 TBCK FB:FBgn0029736 CG4041 Yes Yes 9 9 @@ -13861,8 +13854,8 @@ HGNC:17039 TMEM259 FB:FBgn0034071 CG8405 Yes Yes 8 9 HGNC:28550 TMEM26 FB:FBgn0039429 CG14238 Yes Yes 5 9 HGNC:26139 TMEM267 FB:FBgn0035475 CG10866 Yes Yes 9 9 HGNC:24513 TMEM268 FB:FBgn0028527 CG18507 Yes Yes 3 9 -HGNC:16667 TMEM30A FB:FBgn0030752 CDC50 Yes Yes 8 9 -HGNC:27254 TMEM30B FB:FBgn0030752 CDC50 Yes No 6 9 +HGNC:16667 TMEM30A FB:FBgn0030752 Cdc50 Yes Yes 8 9 +HGNC:27254 TMEM30B FB:FBgn0030752 Cdc50 Yes No 6 9 HGNC:25541 TMEM33 FB:FBgn0266449 Kr-h2 Yes Yes 9 9 HGNC:25864 TMEM35A FB:FBgn0025712 CG13920 Yes Yes 8 9 HGNC:28462 TMEM38A FB:FBgn0030745 CG4239 Yes Yes 8 9 @@ -13871,7 +13864,7 @@ HGNC:25600 TMEM39A FB:FBgn0033899 CG13016 Yes Yes 9 9 HGNC:25510 TMEM39B FB:FBgn0033899 CG13016 Yes Yes 9 9 HGNC:28948 TMEM41B FB:FBgn0030850 stas Yes Yes 9 9 HGNC:28444 TMEM42 FB:FBgn0260027 CG42495 Yes Yes 4 9 -HGNC:28472 TMEM43 FB:FBgn0035825 CG8111 Yes Yes 9 9 +HGNC:28472 TMEM43 FB:FBgn0035825 Tmem43 Yes Yes 9 9 HGNC:18515 TMEM47 FB:FBgn0266409 CG45049 Yes Yes 8 9 HGNC:30590 TMEM50A FB:FBgn0035528 CG15012 Yes Yes 9 9 HGNC:1280 TMEM50B FB:FBgn0035528 CG15012 Yes Yes 9 9 @@ -13896,7 +13889,7 @@ HGNC:21427 TMEM8B FB:FBgn0039290 CG13654 Yes Yes 6 9 HGNC:18823 TMEM9 FB:FBgn0037313 CG1161 Yes Yes 7 9 HGNC:28983 TMEM94 FB:FBgn0022153 l(2)k05819 Yes Yes 8 9 HGNC:1168 TMEM9B FB:FBgn0037313 CG1161 Yes Yes 7 9 -HGNC:11870 TMF1 FB:FBgn0029912 CG4557 Yes Yes 7 9 +HGNC:11870 TMF1 FB:FBgn0029912 Tmf Yes Yes 7 9 HGNC:30800 TMIE FB:FBgn0032860 CG15130 Yes Yes 5 9 HGNC:18308 TMLHE FB:FBgn0038795 Tmlh Yes Yes 8 9 HGNC:11871 TMOD1 FB:FBgn0082582 tmod Yes Yes 8 9 @@ -13989,8 +13982,8 @@ HGNC:20161 TOX4 FB:FBgn0035238 CG12104 Yes No 4 9 HGNC:11998 TP53 FB:FBgn0039044 p53 Yes Yes 5 9 HGNC:12000 TP53BP2 FB:FBgn0034606 ASPP Yes Yes 8 9 HGNC:25102 TP53I13 FB:FBgn0035372 CG12093 Yes Yes 3 9 -HGNC:18022 TP53INP1 FB:FBgn0035542 DOR Yes Yes 5 9 -HGNC:16104 TP53INP2 FB:FBgn0035542 DOR Yes Yes 5 9 +HGNC:18022 TP53INP1 FB:FBgn0035542 TP53INP Yes Yes 5 9 +HGNC:16104 TP53INP2 FB:FBgn0035542 TP53INP Yes Yes 5 9 HGNC:16197 TP53RK FB:FBgn0035590 Tcs5 Yes Yes 9 9 HGNC:15979 TP63 FB:FBgn0039044 p53 Yes No 4 9 HGNC:12003 TP73 FB:FBgn0039044 p53 Yes No 4 9 @@ -14001,8 +13994,8 @@ HGNC:12006 TPD52L1 FB:FBgn0034345 CG5174 Yes No 5 9 HGNC:12007 TPD52L2 FB:FBgn0034345 CG5174 Yes Yes 7 9 HGNC:23382 TPD52L3 FB:FBgn0034345 CG5174 Yes No 5 9 HGNC:24561 TPGS2 FB:FBgn0036236 CG6931 Yes Yes 9 9 -HGNC:12008 TPH1 FB:FBgn0035187 Trh Yes Yes 9 9 -HGNC:20692 TPH2 FB:FBgn0035187 Trh Yes No 8 9 +HGNC:12008 TPH1 FB:FBgn0035187 Trhn Yes Yes 9 9 +HGNC:20692 TPH2 FB:FBgn0035187 Trhn Yes No 8 9 HGNC:12009 TPI1 FB:FBgn0086355 Tpi Yes Yes 9 9 HGNC:17358 TPK1 FB:FBgn0037942 CG14721 Yes Yes 9 9 HGNC:12010 TPM1 FB:FBgn0003721 Tm1 Yes Yes 7 9 @@ -14016,7 +14009,7 @@ HGNC:12016 TPP2 FB:FBgn0020370 TppII Yes Yes 9 9 HGNC:24164 TPPP FB:FBgn0266417 ringer Yes Yes 9 9 HGNC:19293 TPPP2 FB:FBgn0266417 ringer Yes No 8 9 HGNC:24162 TPPP3 FB:FBgn0266417 ringer Yes Yes 9 9 -HGNC:12017 TPR FB:FBgn0013756 Mtor Yes Yes 8 9 +HGNC:12017 TPR FB:FBgn0013756 Mgtor Yes Yes 8 9 HGNC:12020 TPST1 FB:FBgn0086674 Tpst Yes Yes 8 9 HGNC:12021 TPST2 FB:FBgn0086674 Tpst Yes Yes 8 9 HGNC:12022 TPT1 FB:FBgn0037874 Tctp Yes Yes 9 9 @@ -14917,8 +14910,11 @@ HGNC:12576 UPP1 FB:FBgn0039464 CG6330 Yes Yes 8 9 HGNC:23061 UPP2 FB:FBgn0034800 CG3788 Yes Yes 8 9 HGNC:23061 UPP2 FB:FBgn0039464 CG6330 Yes Yes 8 9 HGNC:28334 UPRT FB:FBgn0035639 kri Yes Yes 9 9 -HGNC:15891 UQCC1 FB:FBgn0035722 CG10075 Yes Yes 9 9 +HGNC:15891 UQCC1 FB:FBgn0035722 Uqcc1 Yes Yes 9 9 HGNC:21237 UQCC2 FB:FBgn0287589 CG46459 Yes Yes 7 9 +HGNC:27558 UQCC4 FB:FBgn0050373 CG30373 Yes Yes 2 9 +HGNC:37257 UQCC5 FB:FBgn0052736 sloth1 Yes Yes 9 9 +HGNC:34450 UQCC6 FB:FBgn0259204 sloth2 Yes Yes 5 9 HGNC:30863 UQCR10 FB:FBgn0011227 ox Yes Yes 8 9 HGNC:30862 UQCR11 FB:FBgn0034245 UQCR-6.4 Yes Yes 3 9 HGNC:12582 UQCRB FB:FBgn0030733 UQCR-14 Yes Yes 9 9 @@ -15324,7 +15320,6 @@ HGNC:13085 ZBTB22 FB:FBgn0264442 ab Yes Yes 2 9 HGNC:25001 ZBTB44 FB:FBgn0051224 CG31224 Yes Yes 2 9 HGNC:4930 ZBTB48 FB:FBgn0035702 CG10147 Yes Yes 2 9 HGNC:4930 ZBTB48 FB:FBgn0266450 Kr-h1 Yes Yes 2 9 -HGNC:24094 ZBTB8OS FB:FBgn0038893 Archease Yes Yes 9 9 HGNC:24277 ZC2HC1A FB:FBgn0261561 CG42675 Yes Yes 3 9 HGNC:21174 ZC2HC1B FB:FBgn0261561 CG42675 Yes Yes 3 9 HGNC:26259 ZC3H12A FB:FBgn0038769 Regnase-1 Yes Yes 8 9 @@ -15434,7 +15429,7 @@ HGNC:13029 ZMYM5 FB:FBgn0010328 woc Yes No 3 9 HGNC:13050 ZMYM6 FB:FBgn0010328 woc Yes No 3 9 HGNC:19412 ZMYND10 FB:FBgn0266709 Zmynd10 Yes Yes 8 9 HGNC:16966 ZMYND11 FB:FBgn0033752 CG8569 Yes Yes 5 9 -HGNC:9397 ZMYND8 FB:FBgn0039863 CG1815 Yes Yes 7 9 +HGNC:9397 ZMYND8 FB:FBgn0039863 Zmynd8 Yes Yes 7 9 HGNC:12879 ZNF10 FB:FBgn0024975 CG2712 Yes Yes 2 9 HGNC:12886 ZNF106 FB:FBgn0038532 CG14322 Yes Yes 2 9 HGNC:12887 ZNF107 FB:FBgn0263490 mld Yes Yes 2 9 From f3f078952fac598c8d08ae15693592bbdb8c72e6 Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Tue, 16 May 2023 14:49:53 +0200 Subject: [PATCH 2/4] fix: modify rxn and met IDs - These ids accidentally conflict with recent changes to HumanGEM --- data/fruitflySpecificMets.tsv | 62 +++++++++++++++++------------------ data/fruitflySpecificRxns.tsv | 62 +++++++++++++++++------------------ 2 files changed, 62 insertions(+), 62 deletions(-) diff --git a/data/fruitflySpecificMets.tsv b/data/fruitflySpecificMets.tsv index 42dc30b..6cfb93a 100644 --- a/data/fruitflySpecificMets.tsv +++ b/data/fruitflySpecificMets.tsv @@ -1,38 +1,38 @@ mets metNames metFormulas metCharges compartments metKEGGID metPubChemID metChEBIID metMetaCycID metMetaNetXID metsNoComp -"MAM20003c" "L-Allothreonine" "C4H9NO3" 0 "c" "C05519" "99289" "CHEBI:28718" "L-ALLO-THREONINE" "MNXM2125" "MAM20003" +"MAM15003c" "L-Allothreonine" "C4H9NO3" 0 "c" "C05519" "99289" "CHEBI:28718" "L-ALLO-THREONINE" "MNXM2125" "MAM15003" "MAM01104x" "5-hydroxyisourate" "C5H4N4O4" 0 "x" "C11821" "250388" "CHEBI:250388" "5-HYDROXYISOURATE" "MNXM1137" "MAM01104" "MAM10018x" "5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate" "C5H5N4O5" -1 "x" "C12248" "443736" "CHEBI:58639" "CPD-5821" "MNXM1805" "MAM10018" "MAM10018c" "5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate" "C5H5N4O5" -1 "c" "C12248" "443736" "CHEBI:58639" "CPD-5821" "MNXM1805" "MAM10018" -"MAM20005x" "1,3,7-Trimethyluric acid" "C8H10N4O3" 0 "x" "C16361" "47205669" "CHEBI:691622" "CPD-12480" "MNXM2761" "MAM20005" -"MAM20006x" "3,6,8-Trimethylallantoin" "C7H12N4O3" 0 "x" "C16362" "47205670" "CHEBI:80471" "CPD-12485" "MNXM6778" "MAM20006" -"MAM20010c" "pseudouridine" "C9H12N2O6" 0 "c" "C02067" "15047" "CHEBI:17802" "CPD-497" "MNXM1094063;MNXM4794" "MAM20010" +"MAM15005x" "1,3,7-Trimethyluric acid" "C8H10N4O3" 0 "x" "C16361" "47205669" "CHEBI:691622" "CPD-12480" "MNXM2761" "MAM15005" +"MAM15006x" "3,6,8-Trimethylallantoin" "C7H12N4O3" 0 "x" "C16362" "47205670" "CHEBI:80471" "CPD-12485" "MNXM6778" "MAM15006" +"MAM15010c" "pseudouridine" "C9H12N2O6" 0 "c" "C02067" "15047" "CHEBI:17802" "CPD-497" "MNXM1094063;MNXM4794" "MAM15010" "MAM02807c" "pseudouridine-5-phosphate" "C9H11N2O9P" -2 "c" "C01168" "25245232" "CHEBI:18116" "PSEUDOURIDINE-5-P" "MNXM2276" "MAM02807" -"MAM20027c" "L-arginine-phosphate" "C6H14N4O5P" -1 "c" "C05945" "92150" "CHEBI:58477" "L-ARGININE-P" "MNXM3663" "MAM20027" -"MAM20028r" "2-2-N-linked-Glycan" "C54H88N6O37" 0 "r" "" "25200901" "CHEBI:60651" "2-2-N-linked-Glycan" "MNXM146421" "MAM20028" -"MAM20029r" "N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F" "C60H98N6O41" 0 "r" "" "25203205" "CHEBI:137182" "N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F" "MNXM148917" "MAM20029" +"MAM15027c" "L-arginine-phosphate" "C6H14N4O5P" -1 "c" "C05945" "92150" "CHEBI:58477" "L-ARGININE-P" "MNXM3663" "MAM15027" +"MAM15028r" "2-2-N-linked-Glycan" "C54H88N6O37" 0 "r" "" "25200901" "CHEBI:60651" "2-2-N-linked-Glycan" "MNXM146421" "MAM15028" +"MAM15029r" "N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F" "C60H98N6O41" 0 "r" "" "25203205" "CHEBI:137182" "N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F" "MNXM148917" "MAM15029" "MAM01948r" "GDP" "C10H12N5O11P2" -3 "r" "C00035" "" "CHEBI:17552" "" "MNXM30" "MAM01948" "MAM01950r" "GDP-L-fucose" "C16H23N5O15P2" -2 "r" "C00325" "" "CHEBI:17009" "" "MNXM193" "MAM01950" -"MAM20030c" "ecdysone" "C27H44O6" 0 "c" "C00477" "19212" "CHEBI:16688" "ECDYSONE" "MNXM727021;MNXM727022" "MAM20030" -"MAM20031c" "3-dehydroecdysone" "C27H42O6" 0 "c" "C02513" "5460083" "CHEBI:17058" "CPD-331" "MNXM819815;MNXM2610" "MAM20031" -"MAM20032c" "20-hydroxyecdysone" "C27H44O7" 0 "c" "C02633" "5459840" "CHEBI:16587" "CPD-276" "MNXM733384" "MAM20032" -"MAM20033c" "2,22,25-trideoxyecdysone" "C27H44O3" 0 "c" "C16493" "15942885" "CHEBI:19290" "CPD-15499" "MNXM6663" "MAM20033" -"MAM20034c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM20034" -"MAM20035c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM20035" -"MAM20036c" "2-deoxyecdysone" "C27H44O5" 0 "c" "C16495" "13939876" "CHEBI:19566" "CPD-15497" "MNXM739340;MNXM739339" "MAM20036" -"MAM20037c" "3-dehydro-2,22,25-deoxyecdysone" "C27H42O3" 0 "c" "C16509" "15081546" "CHEBI:80541" "" "MNXM5425" "MAM20037" -"MAM20038c" "3-dehydro-2,22-dideoxyecdysone" "C27H42O4" 0 "c" "C16498" "23724770" "CHEBI:80533" "" "MNXM6664" "MAM20038" -"MAM20039c" "3-dehydro-2-deoxyecdysone" "C27H42O5" 0 "c" "C16497" "15251159" "CHEBI:80532" "CPD-15506" "MNXM6790" "MAM20039" -"MAM20040c" "3-dehydroecdysone" "C27H42O6" 0 "c" "C02513" "5460083" "CHEBI:17058" "CPD-331" "MNXM819815;MNXM2610" "MAM20040" -"MAM20041c" "20,26-dihydroxyecdysone" "C27H44O8" 0 "c" "C16500" "21123946" "CHEBI:19793" "CPD-15601" "MNXM741791;MNXM741792" "MAM20041" -"MAM20042c" "trans-trans-farnesyl-phosphate" "C15H25O4P" -2 "c" "C20121" "46926298" "CHEBI:88226" "CPD-12587" "MNXM4974" "MAM20042" -"MAM20043c" "2-trans-S-6-trans-farnesol" "C15H26O" 0 "c" "C01126" "445070" "CHEBI:16619" "2-TRANS6-TRANS-FARNESOL" "MNXM727075" "MAM20043" -"MAM20044c" "2-trans-6-trans-farnesal" "C15H24O" 0 "c" "C03461" "5280598" "CHEBI:15894" "2-TRANS6-TRANS-FARNESAL" "MNXM1959" "MAM20044" -"MAM20045c" "alpha-D-glucose 6-phosphate" "C6H11O9P" -2 "c" "C00668" "439284" "CHEBI:17665" "ALPHA-GLC-6-P" "MNXM729990" "MAM20045" -"MAM20046c" "alpha-alpha-trehalose-6-phosphate" "C12H21O14P" -2 "c" "C00689" "122336" "CHEBI:18283" "TREHALOSE-6P" "MNXM448" "MAM20046" -"MAM20047c" "secologanin" "C17H24O10" 0 "c" "C01852" "161276" "CHEBI:18002" "SECOLOGANIN-CPD" "MNXM823" "MAM20047" -"MAM20048c" "3-alphaS-strictosidine" "C27H35N2O9" 1 "c" "C03470" "44123291" "CHEBI:17559" "STRICTOSIDINE" "MNXM728173" "MAM20048" -"MAM20049c" "pyrimidodiazepine" "C9H11N5O2" 0 "c" "C02587" "135887869" "CHEBI:27114" "A-PYRIMIDODIAZEPINE" "MNXM732507" "MAM20049" -"MAM20050c" "Juvenile hormone III" "C16H26O3" 0 "c" "C09694" "5281523" "CHEBI:27493" "CPD-8838" "MNXM2685" "MAM20050" -"MAM20051c" "Juvenile hormone III acid" "C15H23O3" -1 "c" "C16504" "23724771" "CHEBI:83274" "CPD-12750" "MNXM3627" "MAM20051" -"MAM20052c" "farnesoic acid" "C15H24O2" 0 "c" "C16502" "21895630" "CHEBI:83276" "CPD-12585" "MNXM735428" "MAM20052" -"MAM20053c" "methyl farnesoate" "C16H26O2" 0 "c" "C16503" "5275508" "CHEBI:80535" "CPD-12586" "MNXM5369" "MAM20053" +"MAM15030c" "ecdysone" "C27H44O6" 0 "c" "C00477" "19212" "CHEBI:16688" "ECDYSONE" "MNXM727021;MNXM727022" "MAM15030" +"MAM15031c" "3-dehydroecdysone" "C27H42O6" 0 "c" "C02513" "5460083" "CHEBI:17058" "CPD-331" "MNXM819815;MNXM2610" "MAM15031" +"MAM15032c" "20-hydroxyecdysone" "C27H44O7" 0 "c" "C02633" "5459840" "CHEBI:16587" "CPD-276" "MNXM733384" "MAM15032" +"MAM15033c" "2,22,25-trideoxyecdysone" "C27H44O3" 0 "c" "C16493" "15942885" "CHEBI:19290" "CPD-15499" "MNXM6663" "MAM15033" +"MAM15034c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM15034" +"MAM15035c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM15035" +"MAM15036c" "2-deoxyecdysone" "C27H44O5" 0 "c" "C16495" "13939876" "CHEBI:19566" "CPD-15497" "MNXM739340;MNXM739339" "MAM15036" +"MAM15037c" "3-dehydro-2,22,25-deoxyecdysone" "C27H42O3" 0 "c" "C16509" "15081546" "CHEBI:80541" "" "MNXM5425" "MAM15037" +"MAM15038c" "3-dehydro-2,22-dideoxyecdysone" "C27H42O4" 0 "c" "C16498" "23724770" "CHEBI:80533" "" "MNXM6664" "MAM15038" +"MAM15039c" "3-dehydro-2-deoxyecdysone" "C27H42O5" 0 "c" "C16497" "15251159" "CHEBI:80532" "CPD-15506" "MNXM6790" "MAM15039" +"MAM15040c" "3-dehydroecdysone" "C27H42O6" 0 "c" "C02513" "5460083" "CHEBI:17058" "CPD-331" "MNXM819815;MNXM2610" "MAM15040" +"MAM15041c" "20,26-dihydroxyecdysone" "C27H44O8" 0 "c" "C16500" "21123946" "CHEBI:19793" "CPD-15601" "MNXM741791;MNXM741792" "MAM15041" +"MAM15042c" "trans-trans-farnesyl-phosphate" "C15H25O4P" -2 "c" "C20121" "46926298" "CHEBI:88226" "CPD-12587" "MNXM4974" "MAM15042" +"MAM15043c" "2-trans-S-6-trans-farnesol" "C15H26O" 0 "c" "C01126" "445070" "CHEBI:16619" "2-TRANS6-TRANS-FARNESOL" "MNXM727075" "MAM15043" +"MAM15044c" "2-trans-6-trans-farnesal" "C15H24O" 0 "c" "C03461" "5280598" "CHEBI:15894" "2-TRANS6-TRANS-FARNESAL" "MNXM1959" "MAM15044" +"MAM15045c" "alpha-D-glucose 6-phosphate" "C6H11O9P" -2 "c" "C00668" "439284" "CHEBI:17665" "ALPHA-GLC-6-P" "MNXM729990" "MAM15045" +"MAM15046c" "alpha-alpha-trehalose-6-phosphate" "C12H21O14P" -2 "c" "C00689" "122336" "CHEBI:18283" "TREHALOSE-6P" "MNXM448" "MAM15046" +"MAM15047c" "secologanin" "C17H24O10" 0 "c" "C01852" "161276" "CHEBI:18002" "SECOLOGANIN-CPD" "MNXM823" "MAM15047" +"MAM15048c" "3-alphaS-strictosidine" "C27H35N2O9" 1 "c" "C03470" "44123291" "CHEBI:17559" "STRICTOSIDINE" "MNXM728173" "MAM15048" +"MAM15049c" "pyrimidodiazepine" "C9H11N5O2" 0 "c" "C02587" "135887869" "CHEBI:27114" "A-PYRIMIDODIAZEPINE" "MNXM732507" "MAM15049" +"MAM15050c" "Juvenile hormone III" "C16H26O3" 0 "c" "C09694" "5281523" "CHEBI:27493" "CPD-8838" "MNXM2685" "MAM15050" +"MAM15051c" "Juvenile hormone III acid" "C15H23O3" -1 "c" "C16504" "23724771" "CHEBI:83274" "CPD-12750" "MNXM3627" "MAM15051" +"MAM15052c" "farnesoic acid" "C15H24O2" 0 "c" "C16502" "21895630" "CHEBI:83276" "CPD-12585" "MNXM735428" "MAM15052" +"MAM15053c" "methyl farnesoate" "C16H26O2" 0 "c" "C16503" "5275508" "CHEBI:80535" "CPD-12586" "MNXM5369" "MAM15053" diff --git a/data/fruitflySpecificRxns.tsv b/data/fruitflySpecificRxns.tsv index 1428be5..de5fefe 100644 --- a/data/fruitflySpecificRxns.tsv +++ b/data/fruitflySpecificRxns.tsv @@ -1,32 +1,32 @@ rxns equations ub lb eccodes subSystems grRules rxnReferences rxnConfidenceScores rxnKEGGID rxnMetaCycID rxnREACTOMEID rxnMetaNetXID -"MAR20001" "NAD+[m] + threonine[m] => NADH[m] + H+[m] + L-2-amino-3-oxobutanoic acid[m]" 1000 0 "1.1.1.103" "Glycine, serine and threonine metabolism" "CG5955" "PMID:26492815" 4 "R01465" "THREODEHYD-RXN" "R-HSA-6798667" "MNXR103402" -"MAR20003" "L-Allothreonine[c] <=> glycine[c] + acetaldehyde[c]" 1000 -1000 "4.1.2.48;4.1.2.49" "Glycine, serine and threonine metabolism" "CG10184" "" 2 "R06171" "LTAA-RXN" "" "MNXR104834" -"MAR20004" "H2O[x] + 5-hydroxyisourate[x] => 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[x] + H+[x]" 1000 0 "3.5.2.17" "Purine metabolism" "CG30016" "PMID:17085964" 4 "R06601" "3.5.2.17-RXN" "" "MNXR100652" -"MAR20005" "5-hydroxyisourate[x] <=> 5-hydroxyisourate[c]" 1000 -1000 "" "Transport" "" "" 0 "" "" "" "" -"MAR20006" "5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[x] <=> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[c]" 1000 -1000 "" "Transport" "" "" 0 "" "" "" "" -"MAR20007" "2 H2O[x] + O2[x] + 1,3,7-Trimethyluric acid[x] <=> CO2[x] + H2O2[x] + 3,6,8-Trimethylallantoin[x]" 1000 -1000 "1.7.3.3" "Caffeine metabolism" "Uro" "" 2 "R07981" "" "" "MNXR111564" -"MAR20013" "ATP[c] + pseudouridine[c] <=> ADP[c] + pseudouridine-5-phosphate[c] + H+[c]" 1000 -1000 "2.7.1.83" "Pyrimidine metabolism" "CG2794" "" 2 "R03315" "PSEUDOURIDINE-KINASE-RXN" "" "MNXR108088;MNXR162394" -"MAR20014" "NADH[c] + O2[c] + H+[c] + cholesterol[c] => 2 H2O[c] + NAD+[c] + provitamin D3[c]" 1000 0 "1.14.19.21" "Hormone biosynthesis" "nvd" "" 2 "R11007" "RXN-16379" "" "MNXR120043" -"MAR20015" "NADPH[c] + O2[c] + H+[c] + cholesterol[c] => 2 H2O[c] + NADP+[c] + provitamin D3[c]" 1000 0 "1.14.19.21" "Hormone biosynthesis" "nvd" "" 2 "R11008" "RXN-16379" "" "MNXR120043" -"MAR20017" "NADH[c] + AKG[c] + glutamine[c] + H+[c] => NAD+[c] + 2 glutamate[c]" 1000 0 "14.1.14" "Alanine, aspartate and glutamate metabolism" "GS" "" 2 "R00093" "GLUTAMATE-SYNTHASE-NADH-RXN" "" "MNXR100289" -"MAR20035" "ATP[c] + arginine[c] <=> ADP[c] + L-arginine-phosphate[c] + H+[c]" 1000 -1000 "2.7.3.3" "Arginine and proline metabolism" "Argk or AK-3 or CG5144" "" 2 "R00554" "ARGININE-KINASE-RXN" "" "MNXR95943" -"MAR20036" "2-2-N-linked-Glycan[r] + GDP-L-fucose[r] => N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F[r] + GDP[r] + H+[r]" 1000 0 "2.4.1.214" "N-glycan metabolism" "FucTA" "" 2 "" "2.4.1.214-RXN" "" "MNXR143743" -"MAR20037" "O2[c] + ecdysone[c] => H2O2[c] + 3-dehydroecdysone[c]" 1000 0 "1.1.3.16" "Hormone biosynthesis" "Eo" "" 2 "R02373" "ECDYSONE-OXIDASE-RXN" "" "MNXR107471" -"MAR20038" "O2[c] + ecdysone[c] + 2 H+[c] => H2O[c] + 20-hydroxyecdysone[c]" 1000 0 "1.14.99.22" "Hormone biosynthesis" "shd" "" 2 "R02374" "ECDYSONE-20-MONOOXYGENASE-RXN" "" "MNXR107472" -"MAR20039" "provitamin D3[c] => 3-dehydro-2,22,25-deoxyecdysone[c]" 1000 0 "" "Hormone biosynthesis" "spo or spok" "" 2 "R08132" "" "" "MNXR111710" -"MAR20040" "2,22,25-trideoxyecdysone[c] + O2[c] => H2O[c] + 2,22-dideoxyecdysone[c]" 1000 0 "1.14.14.-" "Hormone biosynthesis" "phm" "" 2 "R08133" "RXN-14677" "" "MNXR111711;MNXR118848" -"MAR20041" "2,22-dideoxyecdysone[c] + O2[c] + 2 H+[c] => 2-deoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "dib" "" 2 "R08134" "RXN-14678" "" "MNXR111712;MNXR118849" -"MAR20042" "2-deoxyecdysone[c] + O2[c] + 2 H+[c] => ecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "sad" "" 2 "R08135" "RXN-14679" "" "MNXR111713;MNXR118850" -"MAR20043" "3-dehydro-2,22,25-deoxyecdysone[c] + O2[c] => 3-dehydro-2,22-dideoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "phm" "" 2 "R08136" "RXN-14680" "" "MNXR111714;MNXR118851" -"MAR20044" "3-dehydro-2,22-dideoxyecdysone[c] + O2[c] + 2 H+[c] => 3-dehydro-2-deoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "dib[m]" "" 2 "R08138" "RXN-14681" "" "MNXR111716;MNXR118852" -"MAR20045" "3-dehydro-2-deoxyecdysone[c] + O2[c] + 2 H+[c] => 3-dehydroecdysone[c] + H2O[c]" 1000 0 "1.14.15.-" "Hormone biosynthesis" "sad" "" 2 "R08139" "RXN-14682" "" "MNXR111717;MNXR118853" -"MAR20046" "20-hydroxyecdysone[c] => 20,26-dihydroxyecdysone[c]" 1000 0 "" "Hormone biosynthesis" "Cyp18a1" "" 2 "R08143" "" "" "MNXR150145" -"MAR20047" "H2O[c] + trans-trans-farnesyl-phosphate[c] => Pi[c] + 2-trans-S-6-trans-farnesol[c]" 1000 0 "3.1.3.-" "Hormone biosynthesis" "CG10352 or CG15739 or CG2680" "" 2 "R08144" "RXN-11777" "" "MNXR111722" -"MAR20048" "NADP+[c] + 2-trans-S-6-trans-farnesol[c] => NADPH[c] + H+[c] + 2-trans-6-trans-farnesal[c]" 1000 0 "1.1.1.216" "Hormone biosynthesis" "CG7090 or antdh or FOHSDR or CG9150 or CG9360" "" 2 "R03264" "FARNESOL-DEHYDROGENASE-RXN" "" "MNXR108058" -"MAR20049" "H2O[c] + Juvenile hormone III[c] => methanol[c] + Juvenile hormone III acid[c] + H+[c]" 1000 0 "3.1.1.59" "Hormone biosynthesis" "Jhe" "" 2 "R08149" "JUVENILE-HORMONE-ESTERASE-RXN" "" "MNXR111727" -"MAR20050" "SAM[c] + Juvenile hormone III acid[c] => SAH[c] + Juvenile hormone III[c]" 1000 0 "2.1.1.325" "Hormone biosynthesis" "jhamt" "" 2 "R08151" "RXN-11771" "" "MNXR111729" -"MAR20051" "SAM[c] + farnesoic acid[c] => SAH[c] + methyl farnesoate[c]" 1000 0 "2.1.1.325" "Hormone biosynthesis" "jhamt" "" 2 "R08147" "RXN-11587" "" "MNXR111725" -"MAR20052" "UDP-glucose[c] + alpha-D-glucose 6-phosphate[c] <=> UDP[c] + alpha-alpha-trehalose-6-phosphate[c]" 1000 0 "2.4.1.15" "Starch and sucrose metabolism" "Tps1" "" 2 "R02737" "" "" "MNXR152261" -"MAR20053" "tryptamine[c] + secologanin[c] => H2O[c] + 3-alphaS-strictosidine[c]" 1000 0 "4.3.3.2" "Indole alkaloid biosynthesis" "Ssl2" "" 2 "R03738" "STRICTOSIDINE-SYNTHASE-RXN" "" "MNXR108386" -"MAR20054" "H2O[c] + O2[c] + L-dopa[c] => CO2[c] + NH3[c] + H2O2[c] + 3,4-dihydroxyphenylacetaldehyde[c]" 1000 0 "4.1.1.107" "Tyrosine metabolism" "amd" "" 2 "R11916" "RXN-19275" "" "MNXR170522" -"MAR20055" "2 GSH[c] + 6-pyruvoyltetrahydropterin[c] => H2O[c] + GSSG[c] + pyrimidodiazepine[c]" 1000 0 "1.5.4.1" "Glutathione metabolism" "se" "" 2 "R03984" "1.5.4.1-RXN" "" "MNXR152018" +"MAR15001" "NAD+[m] + threonine[m] => NADH[m] + H+[m] + L-2-amino-3-oxobutanoic acid[m]" 1000 0 "1.1.1.103" "Glycine, serine and threonine metabolism" "CG5955" "PMID:26492815" 4 "R01465" "THREODEHYD-RXN" "R-HSA-6798667" "MNXR103402" +"MAR15003" "L-Allothreonine[c] <=> glycine[c] + acetaldehyde[c]" 1000 -1000 "4.1.2.48;4.1.2.49" "Glycine, serine and threonine metabolism" "CG10184" "" 2 "R06171" "LTAA-RXN" "" "MNXR104834" +"MAR15004" "H2O[x] + 5-hydroxyisourate[x] => 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[x] + H+[x]" 1000 0 "3.5.2.17" "Purine metabolism" "CG30016" "PMID:17085964" 4 "R06601" "3.5.2.17-RXN" "" "MNXR100652" +"MAR15005" "5-hydroxyisourate[x] <=> 5-hydroxyisourate[c]" 1000 -1000 "" "Transport" "" "" 0 "" "" "" "" +"MAR15006" "5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[x] <=> 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate[c]" 1000 -1000 "" "Transport" "" "" 0 "" "" "" "" +"MAR15007" "2 H2O[x] + O2[x] + 1,3,7-Trimethyluric acid[x] <=> CO2[x] + H2O2[x] + 3,6,8-Trimethylallantoin[x]" 1000 -1000 "1.7.3.3" "Caffeine metabolism" "Uro" "" 2 "R07981" "" "" "MNXR111564" +"MAR15013" "ATP[c] + pseudouridine[c] <=> ADP[c] + pseudouridine-5-phosphate[c] + H+[c]" 1000 -1000 "2.7.1.83" "Pyrimidine metabolism" "CG2794" "" 2 "R03315" "PSEUDOURIDINE-KINASE-RXN" "" "MNXR108088;MNXR162394" +"MAR15014" "NADH[c] + O2[c] + H+[c] + cholesterol[c] => 2 H2O[c] + NAD+[c] + provitamin D3[c]" 1000 0 "1.14.19.21" "Hormone biosynthesis" "nvd" "" 2 "R11007" "RXN-16379" "" "MNXR120043" +"MAR15015" "NADPH[c] + O2[c] + H+[c] + cholesterol[c] => 2 H2O[c] + NADP+[c] + provitamin D3[c]" 1000 0 "1.14.19.21" "Hormone biosynthesis" "nvd" "" 2 "R11008" "RXN-16379" "" "MNXR120043" +"MAR15017" "NADH[c] + AKG[c] + glutamine[c] + H+[c] => NAD+[c] + 2 glutamate[c]" 1000 0 "14.1.14" "Alanine, aspartate and glutamate metabolism" "GS" "" 2 "R00093" "GLUTAMATE-SYNTHASE-NADH-RXN" "" "MNXR100289" +"MAR15035" "ATP[c] + arginine[c] <=> ADP[c] + L-arginine-phosphate[c] + H+[c]" 1000 -1000 "2.7.3.3" "Arginine and proline metabolism" "Argk or AK-3 or CG5144" "" 2 "R00554" "ARGININE-KINASE-RXN" "" "MNXR95943" +"MAR15036" "2-2-N-linked-Glycan[r] + GDP-L-fucose[r] => N4-N-ACETYL-BETA-D-GLUCOSAMINYL-F[r] + GDP[r] + H+[r]" 1000 0 "2.4.1.214" "N-glycan metabolism" "FucTA" "" 2 "" "2.4.1.214-RXN" "" "MNXR143743" +"MAR15037" "O2[c] + ecdysone[c] => H2O2[c] + 3-dehydroecdysone[c]" 1000 0 "1.1.3.16" "Hormone biosynthesis" "Eo" "" 2 "R02373" "ECDYSONE-OXIDASE-RXN" "" "MNXR107471" +"MAR15038" "O2[c] + ecdysone[c] + 2 H+[c] => H2O[c] + 20-hydroxyecdysone[c]" 1000 0 "1.14.99.22" "Hormone biosynthesis" "shd" "" 2 "R02374" "ECDYSONE-20-MONOOXYGENASE-RXN" "" "MNXR107472" +"MAR15039" "provitamin D3[c] => 3-dehydro-2,22,25-deoxyecdysone[c]" 1000 0 "" "Hormone biosynthesis" "spo or spok" "" 2 "R08132" "" "" "MNXR111710" +"MAR15040" "2,22,25-trideoxyecdysone[c] + O2[c] => H2O[c] + 2,22-dideoxyecdysone[c]" 1000 0 "1.14.14.-" "Hormone biosynthesis" "phm" "" 2 "R08133" "RXN-14677" "" "MNXR111711;MNXR118848" +"MAR15041" "2,22-dideoxyecdysone[c] + O2[c] + 2 H+[c] => 2-deoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "dib" "" 2 "R08134" "RXN-14678" "" "MNXR111712;MNXR118849" +"MAR15042" "2-deoxyecdysone[c] + O2[c] + 2 H+[c] => ecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "sad" "" 2 "R08135" "RXN-14679" "" "MNXR111713;MNXR118850" +"MAR15043" "3-dehydro-2,22,25-deoxyecdysone[c] + O2[c] => 3-dehydro-2,22-dideoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "phm" "" 2 "R08136" "RXN-14680" "" "MNXR111714;MNXR118851" +"MAR15044" "3-dehydro-2,22-dideoxyecdysone[c] + O2[c] + 2 H+[c] => 3-dehydro-2-deoxyecdysone[c] + H2O[c]" 1000 0 "" "Hormone biosynthesis" "dib[m]" "" 2 "R08138" "RXN-14681" "" "MNXR111716;MNXR118852" +"MAR15045" "3-dehydro-2-deoxyecdysone[c] + O2[c] + 2 H+[c] => 3-dehydroecdysone[c] + H2O[c]" 1000 0 "1.14.15.-" "Hormone biosynthesis" "sad" "" 2 "R08139" "RXN-14682" "" "MNXR111717;MNXR118853" +"MAR15046" "20-hydroxyecdysone[c] => 20,26-dihydroxyecdysone[c]" 1000 0 "" "Hormone biosynthesis" "Cyp18a1" "" 2 "R08143" "" "" "MNXR150145" +"MAR15047" "H2O[c] + trans-trans-farnesyl-phosphate[c] => Pi[c] + 2-trans-S-6-trans-farnesol[c]" 1000 0 "3.1.3.-" "Hormone biosynthesis" "CG10352 or CG15739 or CG2680" "" 2 "R08144" "RXN-11777" "" "MNXR111722" +"MAR15048" "NADP+[c] + 2-trans-S-6-trans-farnesol[c] => NADPH[c] + H+[c] + 2-trans-6-trans-farnesal[c]" 1000 0 "1.1.1.216" "Hormone biosynthesis" "CG7090 or antdh or FOHSDR or CG9150 or CG9360" "" 2 "R03264" "FARNESOL-DEHYDROGENASE-RXN" "" "MNXR108058" +"MAR15049" "H2O[c] + Juvenile hormone III[c] => methanol[c] + Juvenile hormone III acid[c] + H+[c]" 1000 0 "3.1.1.59" "Hormone biosynthesis" "Jhe" "" 2 "R08149" "JUVENILE-HORMONE-ESTERASE-RXN" "" "MNXR111727" +"MAR15050" "SAM[c] + Juvenile hormone III acid[c] => SAH[c] + Juvenile hormone III[c]" 1000 0 "2.1.1.325" "Hormone biosynthesis" "jhamt" "" 2 "R08151" "RXN-11771" "" "MNXR111729" +"MAR15051" "SAM[c] + farnesoic acid[c] => SAH[c] + methyl farnesoate[c]" 1000 0 "2.1.1.325" "Hormone biosynthesis" "jhamt" "" 2 "R08147" "RXN-11587" "" "MNXR111725" +"MAR15052" "UDP-glucose[c] + alpha-D-glucose 6-phosphate[c] <=> UDP[c] + alpha-alpha-trehalose-6-phosphate[c]" 1000 0 "2.4.1.15" "Starch and sucrose metabolism" "Tps1" "" 2 "R02737" "" "" "MNXR152261" +"MAR15053" "tryptamine[c] + secologanin[c] => H2O[c] + 3-alphaS-strictosidine[c]" 1000 0 "4.3.3.2" "Indole alkaloid biosynthesis" "Ssl2" "" 2 "R03738" "STRICTOSIDINE-SYNTHASE-RXN" "" "MNXR108386" +"MAR15054" "H2O[c] + O2[c] + L-dopa[c] => CO2[c] + NH3[c] + H2O2[c] + 3,4-dihydroxyphenylacetaldehyde[c]" 1000 0 "4.1.1.107" "Tyrosine metabolism" "amd" "" 2 "R11916" "RXN-19275" "" "MNXR170522" +"MAR15055" "2 GSH[c] + 6-pyruvoyltetrahydropterin[c] => H2O[c] + GSSG[c] + pyrimidodiazepine[c]" 1000 0 "1.5.4.1" "Glutathione metabolism" "se" "" 2 "R03984" "1.5.4.1-RXN" "" "MNXR152018" From 6cc7ca09f5f620d6102a3f343d3c3c3397c14b2f Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Tue, 16 May 2023 15:19:54 +0200 Subject: [PATCH 3/4] fix: removed duplicated mets reported in #11 --- data/fruitflySpecificMets.tsv | 2 -- 1 file changed, 2 deletions(-) diff --git a/data/fruitflySpecificMets.tsv b/data/fruitflySpecificMets.tsv index 6cfb93a..145fb11 100644 --- a/data/fruitflySpecificMets.tsv +++ b/data/fruitflySpecificMets.tsv @@ -17,12 +17,10 @@ mets metNames metFormulas metCharges compartments metKEGGID metPubChemID metChEB "MAM15032c" "20-hydroxyecdysone" "C27H44O7" 0 "c" "C02633" "5459840" "CHEBI:16587" "CPD-276" "MNXM733384" "MAM15032" "MAM15033c" "2,22,25-trideoxyecdysone" "C27H44O3" 0 "c" "C16493" "15942885" "CHEBI:19290" "CPD-15499" "MNXM6663" "MAM15033" "MAM15034c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM15034" -"MAM15035c" "2,22-dideoxyecdysone" "C27H44O4" 0 "c" "C16494" "14017685" "CHEBI:80530" "CPD-15498" "MNXM6852" "MAM15035" "MAM15036c" "2-deoxyecdysone" "C27H44O5" 0 "c" "C16495" "13939876" "CHEBI:19566" "CPD-15497" "MNXM739340;MNXM739339" "MAM15036" "MAM15037c" "3-dehydro-2,22,25-deoxyecdysone" "C27H42O3" 0 "c" "C16509" "15081546" "CHEBI:80541" "" "MNXM5425" "MAM15037" "MAM15038c" "3-dehydro-2,22-dideoxyecdysone" "C27H42O4" 0 "c" "C16498" "23724770" "CHEBI:80533" "" "MNXM6664" "MAM15038" "MAM15039c" "3-dehydro-2-deoxyecdysone" "C27H42O5" 0 "c" "C16497" "15251159" "CHEBI:80532" "CPD-15506" "MNXM6790" "MAM15039" -"MAM15040c" "3-dehydroecdysone" "C27H42O6" 0 "c" "C02513" "5460083" "CHEBI:17058" "CPD-331" "MNXM819815;MNXM2610" "MAM15040" "MAM15041c" "20,26-dihydroxyecdysone" "C27H44O8" 0 "c" "C16500" "21123946" "CHEBI:19793" "CPD-15601" "MNXM741791;MNXM741792" "MAM15041" "MAM15042c" "trans-trans-farnesyl-phosphate" "C15H25O4P" -2 "c" "C20121" "46926298" "CHEBI:88226" "CPD-12587" "MNXM4974" "MAM15042" "MAM15043c" "2-trans-S-6-trans-farnesol" "C15H26O" 0 "c" "C01126" "445070" "CHEBI:16619" "2-TRANS6-TRANS-FARNESOL" "MNXM727075" "MAM15043" From d4ac5abffdea8b448a54988c529922129b50a344 Mon Sep 17 00:00:00 2001 From: Hao Wang Date: Tue, 16 May 2023 15:21:05 +0200 Subject: [PATCH 4/4] fix: rename OG pair filename and adapt with `geneShortNames` field --- code/masterScriptFruitflyGEM.m | 3 ++- 1 file changed, 2 insertions(+), 1 deletion(-) diff --git a/code/masterScriptFruitflyGEM.m b/code/masterScriptFruitflyGEM.m index 7590ab0..0632eb2 100644 --- a/code/masterScriptFruitflyGEM.m +++ b/code/masterScriptFruitflyGEM.m @@ -19,7 +19,7 @@ %% Prepare Fruitfly ortholog pairs and species-specific network % get ortholog pairs from human to fruitfly -fruitflyOrthologPairs = extractAllianceGenomeOrthologs('human2FruitflyOrthologs.json'); +fruitflyOrthologPairs = extractAllianceGenomeOrthologs('human2FruitflyOrthologs.tsv'); % load species-specific rxns and mets rxnsToAdd = importTsvFile('fruitflySpecificRxns.tsv'); @@ -44,6 +44,7 @@ exportTsvFile(metAssoc,'../model/metabolites.tsv'); end +fruitflyGEM.geneShortNames = fruitflyGEM.genes; save('../model/Fruitfly-GEM.mat', 'fruitflyGEM'); exportYaml(fruitflyGEM, '../model/Fruitfly-GEM.yml'); fruitflyGEM = annotateGEM(fruitflyGEM,'../model',{'rxn','met'}); % add annotation data to structure