Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

PathWhiz? #407

Open
cbizon opened this issue Aug 13, 2024 · 3 comments
Open

PathWhiz? #407

cbizon opened this issue Aug 13, 2024 · 3 comments

Comments

@cbizon
Copy link

cbizon commented Aug 13, 2024

We are getting a bunch of PathWhiz reactions I think from KG2. e.g. PathWhiz.Reaction:108552. I can't seem to find anything about them though - not a name, or anything else about them. The Pathwhiz site doesn't seem actively maintained and frequently crashes when I go to try to look these up, but even when it is working I can't seem to find them.

(Maybe I'm looking in the wrong place?)

Anyway, without any ability to know what this thing is, do they provide any value? I can filter them out in ARAGORN but are they useful to anybody?

@ecwood
Copy link
Collaborator

ecwood commented Aug 13, 2024

For that reaction, there is an info page on it here: https://pathbank.org/lims#/reactions/108552 (you have to create an account or login as a guest to view it). It seems to have a name of "Fructose 6-phosphate + L-Glutamine → Glucosamine 6-phosphate + L-Glutamic acid" on that site. You are correct that they do not seem to have names in RTX-KG2. We included them in our ETL of SMPDB and PathWhiz because they connect many of the compounds and pathways in those databases. We may need to consider a way to make them more effective to users.

@cbizon
Copy link
Author

cbizon commented Aug 13, 2024

Thanks @ecwood ! FWIW, I do think it would be very helpful to at least get the name and/or some kind of linkout on these reactions.

@cbizon
Copy link
Author

cbizon commented Aug 13, 2024

You don't happen to have a list of those reactions do you? That site is insanely slow for me...

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants