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Composite of activity terms used in small corpus #15

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abargnesi opened this issue Apr 14, 2016 · 0 comments
Open

Composite of activity terms used in small corpus #15

abargnesi opened this issue Apr 14, 2016 · 0 comments
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@abargnesi
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According to the BEL 1.0 specification a compositeAbundance can contain only an abundance term list.

The small_corpus.bel file (line 1574) contains the following:

p(HGNC:VEGFA) increases (composite(act(p(HGNC:ITGB1)),kin(p(HGNC:PRKCA))) increases bp(GOBP:"cell-matrix adhesion"))

The full nanopub for this statement is:

SET Disease = "multiple myeloma"
SET TextLocation = Abstract
SET Evidence = "We show that protein kinase C (PKC) alpha is translocated to the plasma membrane and
activated by adhesion of MM cells to fibronectin and VEGF. We identify beta(1)
integrin modulating VEGF-triggered MM cell migration on fibronectin. We show 
that transient enhancement of MM cell adhesion to fibronectin triggered by VEGF 
is dependent on the activity of both PKC and beta(1) integrin. Moreover, we demonstrate
that PKC alpha is constitutively associated with beta(1) integrin."
SET Citation = {"PubMed","The Journal of biological chemistry","11751905","2002-01-20","Podar K|Tai YT|Lin BK|Narsimhan RP|Sattler M|Kijima T|Salgia R|Gupta D|Chauhan D|Anderson KC",""}
SET Species = 9606 

p(HGNC:VEGFA) increases (composite(act(p(HGNC:ITGB1)),kin(p(HGNC:PRKCA))) increases bp(GOBP:"cell-matrix adhesion"))
@abargnesi abargnesi added the bug label Apr 14, 2016
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