diff --git a/README.md b/README.md index d56c41a..ca93025 100644 --- a/README.md +++ b/README.md @@ -32,7 +32,11 @@ etc. `pard` is a package designed to make those **P**hysicochemical **A**mino acid **R**eplacement **D**istances calculations straightforward with Python. -One typical use is to establish a 'distance' between a wild-type protein and its mutated version. +One typical use is to establish a 'distance' between a wild-type protein and its mutated version. Sometimes, rather +than a distance, a similarity is outputted (e.g. with `the Conformational similarity weight matrix` +[[7]](https://www.sciencedirect.com/science/article/abs/pii/002228369290261H)). The higher the distance, the more +different the two amino acids are. The higher the similarity, the more similar the two amino acids are. Whenever +a distance is not outputted but rather a similarity, a warning (that the user can turn off) will be raised. ### Getting started