diff --git a/tests/input/mock_ncbi_objects.py b/tests/input/mock_ncbi_objects.py new file mode 100644 index 000000000..cb17d652f --- /dev/null +++ b/tests/input/mock_ncbi_objects.py @@ -0,0 +1,3423 @@ +from oaklib.datamodels.association import Association + +NCBI_ASSOCIATIONS = [ + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005524", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ATP binding", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0051117", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ATPase binding", + negated=None, + publications=[], + evidence_type="ISS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004709", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="MAP kinase kinase kinase activity", + negated=None, + publications=["PMID:15542601"], + evidence_type="NAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0051015", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="actin filament binding", + negated=None, + publications=["PMID:14702346"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0045296", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cadherin binding", + negated=None, + publications=["PMID:25468996"], + evidence_type="HDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005516", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="calmodulin binding", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0003682", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="chromatin binding", + negated=None, + publications=["PMID:20551055"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0003690", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="double-stranded DNA binding", + negated=None, + publications=["PMID:6325948"], + evidence_type="NAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0019899", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="enzyme binding", + negated=None, + publications=["PMID:12009895"], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0048408", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor binding", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005006", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor activity", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005006", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor activity", + negated=None, + publications=["PMID:12435727", "PMID:17115032", "PMID:11336639", "PMID:2176151"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005006", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor activity", + negated=None, + publications=["PMID:22732145"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005006", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor activity", + negated=None, + publications=["PMID:2790960", "PMID:6325948"], + evidence_type="NAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0042802", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="identical protein binding", + negated=None, + publications=[ + "PMID:21278786", + "PMID:28988771", + "PMID:18042729", + "PMID:16777603", + "PMID:20007378", + "PMID:21482778", + "PMID:23273428", + "PMID:24135280", + "PMID:31980649", + "PMID:20029029", + "PMID:20359299", + "PMID:23436906", + "PMID:23374349", + "PMID:21480528", + "PMID:19563760", + "PMID:22232519", + "PMID:19650109", + "PMID:23636329", + "PMID:22579287", + "PMID:17148612", + ], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005178", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="integrin binding", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0019900", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="kinase binding", + negated=None, + publications=["PMID:18722344"], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="contributes_to", + object="GO:0030235", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="nitric-oxide synthase regulator activity", + negated=None, + publications=["PMID:12828935"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0005515", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein binding", + negated=None, + publications=[ + "PMID:9020117", + "PMID:10572067", + "PMID:25666625", + "PMID:11896612", + "PMID:9506989", + "PMID:26751287", + "PMID:26005835", + "PMID:15345710", + "PMID:25241761", + "PMID:19172738", + "PMID:15962011", + "PMID:24034250", + "PMID:18542056", + "PMID:21439278", + "PMID:34591642", + "PMID:22298428", + "PMID:21258405", + "PMID:30662352", + "PMID:25594178", + "PMID:23436906", + "PMID:10026169", + "PMID:16273093", + "PMID:16516204", + "PMID:17115032", + "PMID:20153921", + "PMID:7542744", + "PMID:27569582", + "PMID:16843263", + "PMID:9852145", + "PMID:19650109", + "PMID:9355745", + "PMID:20462955", + "PMID:22439932", + "PMID:26280537", + "PMID:18722344", + "PMID:11279102", + "PMID:9135143", + "PMID:2176151", + "PMID:21278786", + "PMID:8887653", + "PMID:17182860", + "PMID:12297050", + "PMID:24076656", + "PMID:12620237", + "PMID:37100772", + "PMID:7797556", + "PMID:28479384", + "PMID:31585087", + "PMID:18273061", + "PMID:24780295", + "PMID:16914641", + "PMID:17726113", + "PMID:15282549", + "PMID:25311788", + "PMID:8305738", + "PMID:23273428", + "PMID:24135280", + "PMID:21706016", + "PMID:7657591", + "PMID:20029029", + "PMID:25873175", + "PMID:14679214", + "PMID:25796184", + "PMID:15225635", + "PMID:20935677", + "PMID:23178489", + "PMID:19602593", + "PMID:8621392", + "PMID:22732145", + "PMID:7693694", + "PMID:17909029", + "PMID:20403327", + "PMID:29844572", + "PMID:23636329", + "PMID:16253990", + "PMID:19167335", + "PMID:16799092", + "PMID:26988023", + "PMID:35384245", + "PMID:23178716", + "PMID:9544989", + "PMID:24854121", + "PMID:28988771", + "PMID:7518560", + "PMID:33420426", + "PMID:19798056", + "PMID:23764002", + "PMID:20624308", + "PMID:16499958", + "PMID:12577067", + "PMID:7685104", + "PMID:20878056", + "PMID:12297049", + "PMID:14966128", + "PMID:10229072", + "PMID:14568990", + "PMID:21822280", + "PMID:22411794", + "PMID:17334392", + "PMID:24658140", + "PMID:25187647", + "PMID:23397142", + "PMID:31980649", + "PMID:19509291", + "PMID:24189400", + "PMID:25353163", + "PMID:25036637", + "PMID:17697999", + "PMID:20562913", + "PMID:21266349", + "PMID:23520446", + "PMID:25970784", + "PMID:24557338", + "PMID:27059931", + "PMID:23866081", + "PMID:8034616", + "PMID:24947832", + "PMID:10805725", + "PMID:8940013", + "PMID:23597562", + "PMID:17148612", + "PMID:25136068", + "PMID:22939624", + "PMID:17599051", + "PMID:20551055", + "PMID:30083275", + "PMID:27956147", + "PMID:15657067", + "PMID:23799367", + "PMID:21376233", + "PMID:21951318", + "PMID:31862538", + "PMID:17126326", + "PMID:9050838", + "PMID:26551075", + "PMID:34591612", + "PMID:9419975", + "PMID:12070153", + "PMID:7993895", + "PMID:18824549", + "PMID:28065597", + "PMID:29455656", + "PMID:18776048", + "PMID:21349850", + "PMID:17284441", + "PMID:21203579", + "PMID:18602463", + "PMID:15590694", + "PMID:20473329", + "PMID:23912460", + "PMID:17403676", + "PMID:2790960", + "PMID:16954185", + "PMID:18046415", + "PMID:20308550", + "PMID:18455122", + "PMID:21278788", + ], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0019901", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein kinase binding", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0019903", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein phosphatase binding", + negated=None, + publications=["PMID:28759036", "PMID:15899872"], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0030296", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein tyrosine kinase activator activity", + negated=None, + publications=["PMID:11336639", "PMID:2176151"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004713", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein tyrosine kinase activity", + negated=None, + publications=["PMID:9890893", "PMID:17599051", "PMID:2472218", "PMID:17115032"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004713", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein tyrosine kinase activity", + negated=None, + publications=["PMID:20878056", "PMID:14702346"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004713", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein tyrosine kinase activity", + negated=None, + publications=["PMID:16076471"], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0030297", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="transmembrane receptor protein tyrosine kinase activator activity", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004714", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="transmembrane receptor protein tyrosine kinase activity", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0004888", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="transmembrane signaling receptor activity", + negated=None, + publications=["PMID:7736574"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0031625", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ubiquitin protein ligase binding", + negated=None, + publications=["PMID:23418353"], + evidence_type="IPI", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="enables", + object="GO:0001618", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="virus receptor activity", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0038134", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ERBB2-EGFR signaling pathway", + negated=None, + publications=["PMID:11336639"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0000165", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="MAPK cascade", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007202", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="activation of phospholipase C activity", + negated=None, + publications=["PMID:12435727"], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0048143", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="astrocyte activation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="acts_upstream_of_or_within", + object="GO:0007166", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cell surface receptor signaling pathway", + negated=None, + publications=["PMID:7736574"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0098609", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cell-cell adhesion", + negated=None, + publications=["PMID:12435727"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071230", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to amino acid stimulus", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071276", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to cadmium ion", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071549", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to dexamethasone stimulus", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071364", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to epidermal growth factor stimulus", + negated=None, + publications=[], + evidence_type="ISS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071392", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to estradiol stimulus", + negated=None, + publications=["PMID:20551055"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071260", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to mechanical stimulus", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0034614", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to reactive oxygen species", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0071466", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cellular response to xenobiotic stimulus", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0021795", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cerebral cortex cell migration", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007623", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="circadian rhythm", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0048546", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="digestive tract morphogenesis", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0016101", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="diterpenoid metabolic process", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0001892", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="embryonic placenta development", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="acts_upstream_of_or_within", + object="GO:0007173", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor signaling pathway", + negated=None, + publications=["PMID:7736574"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007173", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor signaling pathway", + negated=None, + publications=["PMID:12435727", "PMID:9890893"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007173", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor signaling pathway", + negated=None, + publications=["PMID:20878056", "PMID:17655843"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007173", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epidermal growth factor receptor signaling pathway", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0050673", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="epithelial cell proliferation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0061029", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="eyelid development in camera-type eye", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0001942", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="hair follicle development", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042743", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="hydrogen peroxide metabolic process", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007611", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="learning or memory", + negated=None, + publications=[], + evidence_type="ISS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0097421", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="liver regeneration", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0030324", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="lung development", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007494", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="midgut development", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0060571", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="morphogenesis of an epithelial fold", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007275", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="multicellular organism development", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0043066", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of apoptotic process", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0043066", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of apoptotic process", + negated=None, + publications=["PMID:18070883"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1905208", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of cardiocyte differentiation", + negated=None, + publications=["PMID:23069713"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042059", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of epidermal growth factor receptor signaling pathway", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045930", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of mitotic cell cycle", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042177", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="negative regulation of protein catabolic process", + negated=None, + publications=["PMID:17115032"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0022008", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="neurogenesis", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0048812", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="neuron projection morphogenesis", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0001503", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ossification", + negated=None, + publications=["PMID:12925580"], + evidence_type="NAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042698", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ovulation cycle", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0038083", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="peptidyl-tyrosine autophosphorylation", + negated=None, + publications=["PMID:20878056"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0038083", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="peptidyl-tyrosine autophosphorylation", + negated=None, + publications=["PMID:22732145"], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0018108", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="peptidyl-tyrosine phosphorylation", + negated=None, + publications=["PMID:22732145"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045739", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of DNA repair", + negated=None, + publications=["PMID:17115032"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045740", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of DNA replication", + negated=None, + publications=["PMID:17115032"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045893", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of DNA-templated transcription", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0070374", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of ERK1 and ERK2 cascade", + negated=None, + publications=["PMID:20551055"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0070374", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of ERK1 and ERK2 cascade", + negated=None, + publications=["PMID:21673316"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1900087", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of G1/S transition of mitotic cell cycle", + negated=None, + publications=["PMID:18483258"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0043406", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of MAP kinase activity", + negated=None, + publications=["PMID:10572067"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045780", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of bone resorption", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0090263", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of canonical Wnt signaling pathway", + negated=None, + publications=["PMID:20302655"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0030307", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of cell growth", + negated=None, + publications=["PMID:15467833"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0030335", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of cell migration", + negated=None, + publications=["PMID:12435727", "PMID:25678558"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="acts_upstream_of_or_within", + object="GO:0008284", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of cell population proliferation", + negated=None, + publications=["PMID:7736574"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0008284", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of cell population proliferation", + negated=None, + publications=["PMID:27057632"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045737", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of cyclin-dependent protein serine/threonine kinase activity", + negated=None, + publications=["PMID:18483258"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0050679", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of epithelial cell proliferation", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0050679", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of epithelial cell proliferation", + negated=None, + publications=["PMID:10572067"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0048146", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of fibroblast proliferation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0060252", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of glial cell proliferation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0033674", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of kinase activity", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1902895", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of miRNA transcription", + negated=None, + publications=["PMID:21673316"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0070257", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of mucus secretion", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0010750", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of nitric oxide mediated signal transduction", + negated=None, + publications=["PMID:12828935"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1901224", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of non-canonical NF-kappaB signal transduction", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0033138", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of peptidyl-serine phosphorylation", + negated=None, + publications=["PMID:20878056"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0051897", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", + negated=None, + publications=["PMID:17655843"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042327", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of phosphorylation", + negated=None, + publications=["PMID:15082764"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1902722", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of prolactin secretion", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1900020", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of protein kinase C activity", + negated=None, + publications=["PMID:22732145"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:1903078", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of protein localization to plasma membrane", + negated=None, + publications=["PMID:22732145"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0001934", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of protein phosphorylation", + negated=None, + publications=["PMID:20551055"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0048661", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of smooth muscle cell proliferation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0032930", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of superoxide anion generation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0051968", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of synaptic transmission, glutamatergic", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045944", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of transcription by RNA polymerase II", + negated=None, + publications=["PMID:20551055"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0045907", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="positive regulation of vasoconstriction", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0046777", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein autophosphorylation", + negated=None, + publications=["PMID:18070883"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0051205", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein insertion into membrane", + negated=None, + publications=["PMID:12435727"], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0070372", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="regulation of ERK1 and ERK2 cascade", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0046328", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="regulation of JNK cascade", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0050999", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="regulation of nitric-oxide synthase activity", + negated=None, + publications=["PMID:12828935"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0050730", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="regulation of peptidyl-tyrosine phosphorylation", + negated=None, + publications=["PMID:12435727"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0051896", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", + negated=None, + publications=["PMID:26514923"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0070141", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="response to UV-A", + negated=None, + publications=["PMID:18483258"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0051592", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="response to calcium ion", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0033590", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="response to cobalamin", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0033594", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="response to hydroxyisoflavone", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007435", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="salivary gland morphogenesis", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007165", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="signal transduction", + negated=None, + publications=["PMID:10572067"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007165", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="signal transduction", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0046718", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="symbiont entry into host cell", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0043586", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="tongue development", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0006412", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="translation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0007169", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="transmembrane receptor protein tyrosine kinase signaling pathway", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="involved_in", + object="GO:0042311", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="vasodilation", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0000139", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="Golgi membrane", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="part_of", + object="GO:0070435", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="Shc-EGFR complex", + negated=None, + publications=[], + evidence_type="ISS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0016324", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="apical plasma membrane", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="is_active_in", + object="GO:0009925", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="basal plasma membrane", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0016323", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="basolateral plasma membrane", + negated=None, + publications=["PMID:12646923"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0030054", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cell junction", + negated=None, + publications=[], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0009986", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cell surface", + negated=None, + publications=["PMID:25666625"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0030669", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="clathrin-coated endocytic vesicle membrane", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005737", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="cytoplasm", + negated=None, + publications=["PMID:12435727", "PMID:7588596", "PMID:22298428"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0031901", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="early endosome membrane", + negated=None, + publications=["PMID:17714434"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005789", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="endoplasmic reticulum membrane", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="colocalizes_with", + object="GO:0005768", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="endosome", + negated=None, + publications=["PMID:16554368"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005768", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="endosome", + negated=None, + publications=["PMID:22732145", "PMID:17182860", "PMID:14702346"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0010008", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="endosome membrane", + negated=None, + publications=["PMID:22719997"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0010008", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="endosome membrane", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005615", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="extracellular space", + negated=None, + publications=["PMID:9103388"], + evidence_type="NAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005925", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="focal adhesion", + negated=None, + publications=["PMID:21423176"], + evidence_type="HDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0097708", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="intracellular vesicle", + negated=None, + publications=["PMID:11331309"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0016020", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="membrane", + negated=None, + publications=["PMID:12435727"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0045121", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="membrane raft", + negated=None, + publications=["PMID:12009895"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0045121", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="membrane raft", + negated=None, + publications=[], + evidence_type="ISS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0097489", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="multivesicular body, internal vesicle lumen", + negated=None, + publications=["PMID:17714434"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0031965", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="nuclear membrane", + negated=None, + publications=[], + evidence_type="IEA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005634", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="nucleus", + negated=None, + publications=["PMID:20551055", "PMID:12828935", "PMID:17115032"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0048471", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="perinuclear region of cytoplasm", + negated=None, + publications=["PMID:24854121"], + evidence_type="IMP", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="is_active_in", + object="GO:0005886", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="plasma membrane", + negated=None, + publications=["PMID:11331309", "PMID:11336639", "PMID:15611079"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005886", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="plasma membrane", + negated=None, + publications=["PMID:20462955", "PMID:22732145", "PMID:22298428", "PMID:15465819"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="located_in", + object="GO:0005886", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="plasma membrane", + negated=None, + publications=[], + evidence_type="TAS", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="part_of", + object="GO:0032991", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="protein-containing complex", + negated=None, + publications=["PMID:20878056"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="part_of", + object="GO:0043235", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="receptor complex", + negated=None, + publications=[], + evidence_type="IBA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="part_of", + object="GO:0043235", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="receptor complex", + negated=None, + publications=["PMID:23382219"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), + Association( + subject="NCBIGene:1956", + predicate="is_active_in", + object="GO:0032587", + property_values=[], + subject_label="EGFR", + predicate_label=None, + object_label="ruffle membrane", + negated=None, + publications=["PMID:11331309"], + evidence_type="IDA", + supporting_objects=[], + primary_knowledge_source=None, + aggregator_knowledge_source=None, + subject_closure=[], + subject_closure_label=[], + object_closure=[], + object_closure_label=[], + comments=[], + ), +] diff --git a/tests/test_implementations/test_ncbigene.py b/tests/test_implementations/test_ncbigene.py index b00c60e32..345404887 100644 --- a/tests/test_implementations/test_ncbigene.py +++ b/tests/test_implementations/test_ncbigene.py @@ -1,4 +1,5 @@ import unittest +from unittest.mock import MagicMock from xml.etree import ElementTree # noqa S405 from oaklib import get_adapter @@ -8,11 +9,11 @@ ) from tests import CYTOPLASM, INPUT_DIR +from tests.input.mock_ncbi_objects import NCBI_ASSOCIATIONS GENE_PATH = INPUT_DIR / "ncbigene-1956.xml" -# TODO: use mock tests class TestNCBIGene(unittest.TestCase): """ Tests :ref:`NCBIGeneImplementation` @@ -20,14 +21,19 @@ class TestNCBIGene(unittest.TestCase): def setUp(self) -> None: self.adapter = get_adapter("NCBIGene:") + self.mock_assocs = NCBI_ASSOCIATIONS def test_query(self): """Tests basic query.""" - adapter = self.adapter + adapter = MagicMock(spec=AssociationProviderInterface) + adapter.associations.return_value = iter(self.mock_assocs) + if not isinstance(adapter, AssociationProviderInterface): raise TypeError("adapter is not an AssociationProviderInterface") assocs = list(adapter.associations(subjects=["NCBIGene:1956"])) + self.assertEqual(assocs, self.mock_assocs) self.assertGreater(len(assocs), 0) + adapter.associations.assert_called_once_with(subjects=["NCBIGene:1956"]) def test_parse_gene_xml(self): """Tests parsing gene XML.""" diff --git a/tox.ini b/tox.ini index 348a8596c..aed69286d 100644 --- a/tox.ini +++ b/tox.ini @@ -8,6 +8,7 @@ isolated_build = true envlist = format lint + codespell py [testenv] @@ -52,3 +53,20 @@ skip_install = true commands = ruff check src/ tests/ description = Run linters. + +[testenv:codespell] +description = Run spell checker. +skip_install = true +deps = + codespell + tomli # required for getting config from pyproject.toml +commands = codespell src/ tests/ -S tests/input/* -S tests/output/* + +[testenv:codespell-write] +description = Run spell checker and write corrections. +skip_install = true +deps = + codespell + tomli +commands = codespell src/ tests/ --write-changes -S tests/input/* -S tests/output/* +