diff --git a/src/components/Search/index.tsx b/src/components/Search/index.tsx
index 8caa14a338d7..9aa99e8d5903 100644
--- a/src/components/Search/index.tsx
+++ b/src/components/Search/index.tsx
@@ -1,4 +1,4 @@
-import {useNavigation} from '@react-navigation/native';
+import {useIsFocused, useNavigation} from '@react-navigation/native';
 import type {StackNavigationProp} from '@react-navigation/stack';
 import React, {useCallback, useEffect, useRef, useState} from 'react';
 import {View} from 'react-native';
@@ -21,6 +21,7 @@ import * as SearchActions from '@libs/actions/Search';
 import * as DeviceCapabilities from '@libs/DeviceCapabilities';
 import Log from '@libs/Log';
 import memoize from '@libs/memoize';
+import isSearchTopmostCentralPane from '@libs/Navigation/isSearchTopmostCentralPane';
 import * as ReportUtils from '@libs/ReportUtils';
 import * as SearchUtils from '@libs/SearchUtils';
 import Navigation from '@navigation/Navigation';
@@ -92,6 +93,7 @@ function Search({queryJSON, onSearchListScroll, contentContainerStyle}: SearchPr
     // eslint-disable-next-line rulesdir/prefer-shouldUseNarrowLayout-instead-of-isSmallScreenWidth
     const {isSmallScreenWidth, isLargeScreenWidth} = useResponsiveLayout();
     const navigation = useNavigation<StackNavigationProp<AuthScreensParamList>>();
+    const isFocused = useIsFocused();
     const lastSearchResultsRef = useRef<OnyxEntry<SearchResults>>();
     const {setCurrentSearchHash, setSelectedTransactions, selectedTransactions, clearSelectedTransactions, setShouldShowStatusBarLoading, lastSearchType, setLastSearchType} =
         useSearchContext();
@@ -248,6 +250,17 @@ function Search({queryJSON, onSearchListScroll, contentContainerStyle}: SearchPr
         turnOffMobileSelectionMode();
     }, [isSearchResultsEmpty, prevIsSearchResultEmpty]);
 
+    useEffect(
+        () => () => {
+            if (isSearchTopmostCentralPane()) {
+                return;
+            }
+            clearSelectedTransactions();
+            turnOffMobileSelectionMode();
+        },
+        [isFocused, clearSelectedTransactions],
+    );
+
     if (shouldShowLoadingState) {
         return (
             <SearchRowSkeleton