diff --git a/src/compiler/validation.jl b/src/compiler/validation.jl
index 048329de1e..f461a3b0c5 100644
--- a/src/compiler/validation.jl
+++ b/src/compiler/validation.jl
@@ -215,6 +215,28 @@ const libjulia = Ref{Ptr{Cvoid}}(C_NULL)
 # List of methods to location of arg which is the mi/function, then start of args
 const generic_method_offsets = Dict{String, Tuple{Int,Int}}(("jl_f__apply_latest" => (2,3), "ijl_f__apply_latest" => (2,3), "jl_f__call_latest" => (2,3), "ijl_f__call_latest" => (2,3), "jl_f_invoke" => (2,3), "jl_invoke" => (1,3), "jl_apply_generic" => (1,2), "ijl_f_invoke" => (2,3), "ijl_invoke" => (1,3), "ijl_apply_generic" => (1,2)))
 
+@inline function has_method(sig, world::UInt, mt::Union{Nothing,Core.MethodTable})
+    return ccall(:jl_gf_invoke_lookup, Any, (Any, Any, UInt), sig, mt, world) !== nothing
+end
+
+@inline function has_method(sig, world::UInt, mt::Core.Compiler.InternalMethodTable)
+    return has_method(sig, mt.world, nothing)
+end
+
+@inline function has_method(sig, world::UInt, mt::Core.Compiler.OverlayMethodTable)
+    return has_method(sig, mt.mt, mt.world) || has_method(sig, nothing, mt.world)
+end
+
+@inline function is_inactive(tys, world::UInt, mt)
+    if has_method(Tuple{typeof(EnzymeRules.inactive), tys...}, world, mt)
+        return true
+    end
+    if has_method(Tuple{typeof(EnzymeRules.inactive_noinl), tys...}, world, mt)
+        return true
+    end
+    return false
+end
+
 import GPUCompiler: DYNAMIC_CALL, DELAYED_BINDING, RUNTIME_FUNCTION, UNKNOWN_FUNCTION, POINTER_FUNCTION
 import GPUCompiler: backtrace, isintrinsic
 function check_ir!(job, errors, imported, inst::LLVM.CallInst, calls)
@@ -449,7 +471,7 @@ function check_ir!(job, errors, imported, inst::LLVM.CallInst, calls)
                             rep = reinterpret(Ptr{Cvoid}, convert(Csize_t, funclib))
                             funclib = Base.unsafe_pointer_to_objref(rep)
                             tys = [typeof(funclib), Vararg{Any}]
-                            if EnzymeRules.is_inactive_from_sig(Tuple{tys...}; world, method_table) || EnzymeRules.is_inactive_noinl_from_sig(Tuple{tys...}; world, method_table)
+                            if is_inactive(tys, world, method_table)
                                 inactive = LLVM.StringAttribute("enzyme_inactive", "")
                                 LLVM.API.LLVMAddCallSiteAttribute(inst, LLVM.API.LLVMAttributeFunctionIndex, inactive)
                                 nofree = LLVM.EnumAttribute("nofree")
@@ -486,7 +508,7 @@ function check_ir!(job, errors, imported, inst::LLVM.CallInst, calls)
                         end
                         tys = flib.specTypes.parameters
                     end
-                    if EnzymeRules.is_inactive_from_sig(Tuple{tys...}; world, method_table) || EnzymeRules.is_inactive_noinl_from_sig(Tuple{tys...}; world, method_table)
+                    if is_inactive(tys, world, method_table)
                         inactive = LLVM.StringAttribute("enzyme_inactive", "")
                         LLVM.API.LLVMAddCallSiteAttribute(inst, LLVM.API.LLVMAttributeFunctionIndex, inactive)
                         nofree = LLVM.EnumAttribute("nofree")
@@ -558,7 +580,7 @@ function check_ir!(job, errors, imported, inst::LLVM.CallInst, calls)
                     end
                     tys = flib.specTypes.parameters
                 end
-                if EnzymeRules.is_inactive_from_sig(Tuple{tys...}; world, method_table) || EnzymeRules.is_inactive_noinl_from_sig(Tuple{tys...}; world, method_table) 
+                if is_inactive(tys, world, method_table)
                     ofn = LLVM.parent(LLVM.parent(inst))
                     mod = LLVM.parent(ofn)
                     inactive = LLVM.StringAttribute("enzyme_inactive", "")
@@ -725,4 +747,4 @@ function rewrite_union_returns_as_ref(enzymefn::LLVM.Function, off, world, width
         @show cur, off
         @assert false
     end
-end
\ No newline at end of file
+end
diff --git a/src/rules/jitrules.jl b/src/rules/jitrules.jl
index 261aaf1f34..95365f309b 100644
--- a/src/rules/jitrules.jl
+++ b/src/rules/jitrules.jl
@@ -157,7 +157,7 @@ function body_runtime_generic_augfwd(N, Width, wrapped, primttypes)
 
     return quote
         args = ($(wrapped...),)
-
+        
         # TODO: Annotation of return value
         # tt0 = Tuple{$(primtypes...)}
         tt′ = Tuple{$(Types...)}
diff --git a/test/runtests.jl b/test/runtests.jl
index c1d7d49b72..911be62d9d 100644
--- a/test/runtests.jl
+++ b/test/runtests.jl
@@ -720,6 +720,29 @@ end
     @test dweights[1] ≈ 1.
 end
 
+function Valuation1(z,Ls1)
+    @inbounds Ls1[1] = sum(Base.inferencebarrier(z))
+    return nothing
+end
+@testset "Active setindex!" begin
+    v=ones(5)
+    dv=zero(v)
+
+    DV1=Float32[0]
+    DV2=Float32[1]
+
+    Enzyme.autodiff(Reverse,Valuation1,Duplicated(v,dv),Duplicated(DV1,DV2))
+    @test dv[1] ≈ 1.
+    
+    DV1=Float32[0]
+    DV2=Float32[1]
+    v=ones(5)
+    dv=zero(v)
+    dv[1] = 1.    
+    Enzyme.autodiff(Forward,Valuation1,Duplicated(v,dv),Duplicated(DV1,DV2))
+    @test DV2[1] ≈ 1.
+end
+
 @testset "Null init union" begin
     @noinline function unionret(itr, cond)
         if cond