diff --git a/e2e-tests/specs/customizer/general/custom-global-colors.spec.ts b/e2e-tests/specs/customizer/general/custom-global-colors.spec.ts
index 6eaa6832d7..755f74b20a 100644
--- a/e2e-tests/specs/customizer/general/custom-global-colors.spec.ts
+++ b/e2e-tests/specs/customizer/general/custom-global-colors.spec.ts
@@ -33,10 +33,12 @@ test.describe('Custom Global Color Control', () => {
 		);
 		await clearWelcome(page);
 
-		await page.waitForTimeout( 200 );
-		await page.locator( '.block-editor-default-block-appender__content' ).click();
-
-		await page.locator('.block-editor-rich-text__editable').first().click();
+		const iframeElement = await page.waitForSelector('iframe');
+		const frame = await iframeElement.contentFrame();
+		if (frame) {
+			await frame.waitForSelector('.block-editor-rich-text__editable');
+			await frame.locator('.block-editor-rich-text__editable').first().click();
+		}
 		// use Background color control to open the color picker, available since WP 6.1
 		await page.getByRole('button', { name: 'Background' }).click();
 		await page.getByRole('option', { name: 'Color: Custom 1' }).click();