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CITEseq_Screening_CARs

code for paper "A Multimodal multimodal single cell assay identifies optimized binders for a bicistronic CAR against GPC2 OR CD276 to overcome heterogeneity in treating Neuroblastoma"

  1. CARpipeline is used to detect CAR identity per cell.
  2. CITEseqRscript is used to process CITE-seq data before and after addding CAR identities data

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using CITEseq to screen optimal CARs

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  • R 53.6%
  • Shell 34.4%
  • Python 12.0%