Skip to content

TFA inference with perturbation data

Compare
Choose a tag to compare
@czma czma released this 27 Sep 00:11
· 1 commit to master since this release

Includes the necessary code and input files to replicate Fig2A of
Inferring TF activities and activity regulators from gene expression data with constraints from TF perturbation data
Ma & Brent, 2020

NetworkConstruction - create the TF-target gene regulatory networks from ChIP, PWM, and DE data
TFA_Optimization - optimize TFA and CS values using a network and gene expression data
evaluateTFA.py - run evaluation metrics on inferred TFA values