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DESCRIPTION
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DESCRIPTION
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Package: RCAS
Type: Package
Title: RNA Centric Annotation System
Version: 1.29.3
Date: 2021-11-21
Authors@R: c(person("Bora", "Uyar", email='[email protected]', role=c("aut", "cre")),
person("Dilmurat", "Yusuf", role=c("aut")),
person("Ricardo", "Wurmus", role=c("aut")),
person("Altuna", "Akalin", role=c("aut")))
Description: RCAS is an R/Bioconductor package designed as a generic reporting tool for the
functional analysis of transcriptome-wide regions of interest detected by
high-throughput experiments. Such transcriptomic regions could be, for instance,
signal peaks detected by CLIP-Seq analysis for protein-RNA interaction sites,
RNA modification sites (alias the epitranscriptome), CAGE-tag locations, or any
other collection of query regions at the level of the transcriptome. RCAS
produces in-depth annotation summaries and coverage profiles based on the
distribution of the query regions with respect to transcript features (exons,
introns, 5'/3' UTR regions, exon-intron boundaries, promoter regions). Moreover,
RCAS can carry out functional enrichment analyses and discriminative motif
discovery.
License: Artistic-2.0
LazyData: TRUE
Depends: R (>= 3.3.0),
plotly (>= 4.5.2),
DT (>= 0.2),
data.table,
Imports:
GenomicRanges,
IRanges,
BSgenome,
BSgenome.Hsapiens.UCSC.hg19,
GenomeInfoDb (>= 1.12.0),
Biostrings,
rtracklayer,
GenomicFeatures,
rmarkdown (>= 0.9.5),
genomation (>= 1.5.5),
knitr (>= 1.12.3),
BiocGenerics,
S4Vectors,
plotrix,
pbapply,
RSQLite,
proxy,
pheatmap,
ggplot2,
cowplot,
seqLogo,
utils,
ranger,
gprofiler2
RoxygenNote: 7.2.3
Suggests: testthat,
covr,
BiocManager
SystemRequirements: pandoc (>= 1.12.3)
VignetteBuilder: knitr
biocViews: Software, GeneTarget, MotifAnnotation, MotifDiscovery, GO, Transcriptomics, GenomeAnnotation, GeneSetEnrichment, Coverage