diff --git a/app/package.json b/app/package.json
index 3ea9bdcc77..0c98748739 100644
--- a/app/package.json
+++ b/app/package.json
@@ -108,9 +108,9 @@
     "test:e2e:ui": "playwright test --ui",
     "dev": "pnpm run dev:server & pnpm run build:static && pnpm run build:relay && vite",
     "dev:ui": "pnpm run build:static && pnpm run build:relay && vite",
-    "dev:server": "source .env && python -m phoenix.server.main --dev serve",
+    "dev:server": "source .env && tox r -e phoenix_main -- --dev serve",
     "dev:server:test": "node ./tests/utils/testServer.mjs",
-    "dev:server:init": "python -m phoenix.server.main --dev serve --with-trace-fixtures=llama_index_rag --with-projects=demo_llama_index --force-fixture-ingestion",
+    "dev:server:init": "tox r -e phoenix_main -- --dev serve --with-trace-fixtures=llama_index_rag --with-projects=demo_llama_index --force-fixture-ingestion",
     "typecheck": "tsc --noEmit",
     "lint": "eslint ./src",
     "prettier": "prettier --write './src/**/*'",
diff --git a/tox.ini b/tox.ini
index 8f93e5404d..4f2d1e12bd 100644
--- a/tox.ini
+++ b/tox.ini
@@ -114,3 +114,15 @@ allowlist_externals =
 commands =
   unlink evals
   unlink otel
+
+[testenv:phoenix_main]
+pass_env=
+  PHOENIX_PORT
+  PHOENIX_GRPC_PORT
+  PHOENIX_HOST_ROOT_PATH
+  PHOENIX_SQL_DATABASE_URL
+  PHOENIX_SQL_DATABASE_SCHEMA
+commands_pre =
+  uv tool install --compile-bytecode --reinstall-package arize-phoenix arize-phoenix@.
+commands =
+  uv tool run arize-phoenix {posargs:serve}