diff --git a/Lib/test/.ruff.toml b/Lib/test/.ruff.toml
index 329a3b4fba6b5b..70013a4757718d 100644
--- a/Lib/test/.ruff.toml
+++ b/Lib/test/.ruff.toml
@@ -1,12 +1,24 @@
 fix = true
 select = [
-    "F811",  # Redefinition of unused variable (useful for finding test methods with the same name)
+    "F"  # select all pyflakes rules by default
+]
+ignore = [
+    "F401",  # unused import
+    "F402",  # Import shadowed by loop variable
+    "F403",  # Don't use "from foo import *"
+    "F405",  # Variable is either undefined or defined from star imports
+    "F541",  # f-string without any placeholders
+    "F821",  # Undefined name
+    "F841",  # Local variable assigned to but never used
 ]
 extend-exclude = [
     # Excluded (run with the other AC files in its own separate ruff job in pre-commit)
     "test_clinic.py",
     # Excluded (these aren't actually executed, they're just "data files")
+    "test_*/badsyntax*.py",
+    "test_inspect/inspect_fodder*.py",
     "tokenizedata/*.py",
+    "typinganndata/ann_module*.py",
     # Failed to lint
     "encoded_modules/module_iso_8859_1.py",
     "encoded_modules/module_koi8_r.py",
@@ -28,3 +40,8 @@ extend-exclude = [
     "test_yield_from.py",
     "time_hashlib.py",
 ]
+
+[per-file-ignores]
+"test_print.py" = ["F633"]  # Use of >> is invalid with print function
+"test_str.py" = ["F504", "F521", "F523"]  # Various formatting error codes
+"test_typing.py" = ["F722"]  # invalid syntax in forward annotation
diff --git a/Lib/test/test_compile.py b/Lib/test/test_compile.py
index c4452e38934cf8..37480938d5d149 100644
--- a/Lib/test/test_compile.py
+++ b/Lib/test/test_compile.py
@@ -992,7 +992,7 @@ def no_code1():
             "doc string"
 
         def no_code2():
-            a: int
+            a: int  # noqa: F842
 
         for func in (no_code1, no_code2):
             with self.subTest(func=func):
diff --git a/Lib/test/test_format.py b/Lib/test/test_format.py
index 6fa49dbc0b730c..dce8fa1faa6dd7 100644
--- a/Lib/test/test_format.py
+++ b/Lib/test/test_format.py
@@ -618,7 +618,7 @@ def test_specifier_z_error(self):
 
         error_msg = re.escape("unsupported format character 'z'")
         with self.assertRaisesRegex(ValueError, error_msg):
-            "%z.1f" % 0  # not allowed in old style string interpolation
+            "%z.1f" % 0  # noqa: F509  # not allowed in old style string interpolation
         with self.assertRaisesRegex(ValueError, error_msg):
             b"%z.1f" % 0
 
diff --git a/Lib/test/test_long.py b/Lib/test/test_long.py
index d299c34cec076d..84eeae425ba2bd 100644
--- a/Lib/test/test_long.py
+++ b/Lib/test/test_long.py
@@ -1429,7 +1429,6 @@ def equivalent_python(byte_array, byteorder, signed=False):
             b'\x01\xff': -255,
             b'\x00\xff': -256,
             b'\xff\x00': 255,
-            b'\x00\x01': 256,
             b'\xff\x7f': 32767,
             b'\x00\x80': -32768,
             b'\xff\xff\x00': 65535,
diff --git a/Lib/test/test_peepholer.py b/Lib/test/test_peepholer.py
index b825b27060e86b..f34a8017df4e6a 100644
--- a/Lib/test/test_peepholer.py
+++ b/Lib/test/test_peepholer.py
@@ -767,7 +767,7 @@ def f():
             try:
                 1 / 0
             except:
-                print(a, b, c, d, e, f, g)
+                print(a, b, c, d, e, f, g)  # noqa: F823
             a = b = c = d = e = f = g = 1
         self.assertInBytecode(f, 'LOAD_FAST_CHECK')
         self.assertNotInBytecode(f, 'LOAD_FAST')
diff --git a/Lib/test/test_string.py b/Lib/test/test_string.py
index 824b89ad517c12..69a302d7a94054 100644
--- a/Lib/test/test_string.py
+++ b/Lib/test/test_string.py
@@ -56,7 +56,7 @@ def test_auto_numbering(self):
         self.assertEqual(fmt.format('foo{}{}', 'bar', 6),
                          'foo{}{}'.format('bar', 6))
         self.assertEqual(fmt.format('foo{1}{num}{1}', None, 'bar', num=6),
-                         'foo{1}{num}{1}'.format(None, 'bar', num=6))
+                         'foo{1}{num}{1}'.format(None, 'bar', num=6))  # noqa: F523
         self.assertEqual(fmt.format('{:^{}}', 'bar', 6),
                          '{:^{}}'.format('bar', 6))
         self.assertEqual(fmt.format('{:^{}} {}', 'bar', 6, 'X'),
diff --git a/Lib/test/test_warnings/__init__.py b/Lib/test/test_warnings/__init__.py
index 83237f5fe0d1b3..9710cdc449c59c 100644
--- a/Lib/test/test_warnings/__init__.py
+++ b/Lib/test/test_warnings/__init__.py
@@ -565,7 +565,7 @@ def test_bad_str(self):
         class BadStrWarning(Warning):
             """Warning with a bad format string for __str__."""
             def __str__(self):
-                return ("A bad formatted string %(err)" %
+                return ("A bad formatted string %(err)" %  # noqa: F501
                         {"err" : "there is no %(err)s"})
 
         with self.assertRaises(ValueError):